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We study Flow Matching in a semi-discrete setting where a Gaussian source is transported toward a discrete target supported on finitely many points. This semi-discrete regime is the theoretical setting behind the use of Flow Matching for…

Machine Learning · Computer Science 2026-05-11 Emile Pierret , Johannes Hertrich , Samuel Hurault , Julie Delon

Morphogenesis is the ensemble of processes that determines form, shape and patterns in organisms. Based on a reaction-diffusion theoretical setting and some prototype reaction schemes, we make a review of the models and experiments that…

Cell Behavior · Quantitative Biology 2007-05-23 Rui Dilao

Diffusion models have emerged as powerful tools for high-quality image generation and editing, but guiding these models to produce specific outputs remains a challenge. Conventional approaches rely on conditioning mechanisms, such as text…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Nithesh Chandher Karthikeyan , Jonas Unger , Gabriel Eilertsen

We consider the role of network geometry in two types of diffusion processes: transport of constant-density information packets with queuing on nodes, and constant voltage-driven tunneling of electrons. The underlying network is a…

Statistical Mechanics · Physics 2010-10-05 Milovan Suvakov , Bosiljka Tadic

A deterministic pathogen transmission model based on high-fidelity physics has been developed. The model combines computational fluid dynamics and computational crowd dynamics in order to be able to provide accurate tracing of viral matter…

Numerical Analysis · Mathematics 2022-10-26 Rainald Löhner , Harbir Antil , Juan Marcelo Gimenez , Sergio Idelsohn , Eugenio Oñate

Diffusion models recently developed for generative AI tasks can produce high-quality samples while still maintaining diversity among samples to promote mode coverage, providing a promising path for learning stochastic closure models.…

Machine Learning · Computer Science 2026-02-20 Xinghao Dong , Huchen Yang , Jin-long Wu

This paper introduces a diffusion-based planner for leader--follower formation control in cluttered environments. The diffusion policy is used to generate the trajectory of the midpoint of two leaders as a rigid bar in the plane, thereby…

Robotics · Computer Science 2026-01-19 Hieu Do Quang , Chien Truong-Quoc , Quoc Van Tran

Biomolecular motors use free energy to drive a variety of cellular tasks, including the transport of cargo, such as vesicles and organelles. We find that the widely-used `constant-force' approximation for the effect of cargo on motor…

Statistical Mechanics · Physics 2023-04-11 Aidan I Brown , David A Sivak

Diffusion models without guidance generate very unrealistic samples. Guidance is used ubiquitously, and previous research has attributed its effect to low-temperature sampling that improves quality by trading off diversity. However, this…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Shanchuan Lin , Xiao Yang

When a fluid carrying a passive solute flows quickly through porous media, three key macroscale transport mechanisms occur. These mechanisms are diffusion, advection and dispersion, all of which depend on the microstructure of the porous…

Fluid Dynamics · Physics 2024-10-16 Lucy C Auton , Mohit P. Dalwadi , Ian M. Griffiths

The diffusive arrival of transcription factors at the promoter sites on the DNA sets a lower bound on how accurately a cell can regulate its protein levels. Using results from the literature on diffusion-influenced reactions, we derive an…

Molecular Networks · Quantitative Biology 2014-10-24 Joris Paijmans , Pieter Rein ten Wolde

This paper explores the computational complexity of diffusion-based language modeling. We prove a dichotomy based on the quality of the score-matching network in a diffusion model. In one direction, a network that exactly computes the score…

Computational Complexity · Computer Science 2025-07-18 Yuxi Liu

Protein structure prediction is pivotal for understanding the structure-function relationship of proteins, advancing biological research, and facilitating pharmaceutical development and experimental design. While deep learning methods and…

Machine Learning · Computer Science 2024-12-30 Kaihui Cheng , Ce Liu , Qingkun Su , Jun Wang , Liwei Zhang , Yining Tang , Yao Yao , Siyu Zhu , Yuan Qi

Diffusion models have marked a significant milestone in the enhancement of image and video generation technologies. However, generating videos that precisely retain the shape and location of moving objects such as robots remains a…

Robotics · Computer Science 2024-07-04 Peng Wang , Zhihao Guo , Abdul Latheef Sait , Minh Huy Pham

Diffusion-based generative models (DBGMs) perturb data to a target noise distribution and reverse this process to generate samples. The choice of noising process, or inference diffusion process, affects both likelihoods and sample quality.…

Machine Learning · Computer Science 2023-03-06 Raghav Singhal , Mark Goldstein , Rajesh Ranganath

Molecular signalling in living cells occurs at low copy numbers and is thereby inherently limited by the noise imposed by thermal diffusion. The precision at which biochemical receptors can count signalling molecules is intimately related…

Statistical Mechanics · Physics 2016-09-26 Aljaz Godec , Ralf Metzler

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Diffusion models have revolutionized generative tasks through high-fidelity outputs, yet flow matching (FM) offers faster inference and empirical performance gains. However, current foundation FM models are computationally prohibitive for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Johannes Schusterbauer , Ming Gui , Frank Fundel , Björn Ommer

Diffusion models are a class of generative models that learn to synthesize samples by inverting a diffusion process that gradually maps data into noise. While these models have enjoyed great success recently, a full theoretical…

Machine Learning · Computer Science 2023-09-22 Raja Marjieh , Ilia Sucholutsky , Thomas A. Langlois , Nori Jacoby , Thomas L. Griffiths

Single-file transport refers to the motion of particles in a narrow channel, such that they cannot bypass each other. This constraint leads to strong correlations between the particles, described by correlation profiles, which measure the…

Statistical Mechanics · Physics 2024-02-09 Aurélien Grabsch , Théotim Berlioz , Pierre Rizkallah , Pierre Illien , Olivier Bénichou