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Although several optical techniques have been recently developed in order to overcome the resolution limit in microscopy, the imaging of sub-wavelength features is still a real challenge. In practise, super-resolution techniques remain…

Physics Education · Physics 2019-07-24 Stephane Perrin , Keshia Badu , Paul Montgomery , Sylvain Lecler

The production of pairs of entangled photons simply by focusing a laser beam onto a crystal with a non-linear optical response was used to test quantum mechanics and to open new approaches in imaging. The development of the latter was…

Quantum Physics · Physics 2019-08-09 Paul-Antoine Moreau , Ermes Toninelli , Thomas Gregory , Miles J. Padgett

Confocal laser-scanning microscopy (CLSM) is one of the most popular optical architectures for fluorescence imaging. In CLSM, a focused laser beam excites the fluorescence emission from a specific specimen position. Some actuators scan the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Alessandro Zunino , Marco Castello , Giuseppe Vicidomini

Structured illumination microscopy (SIM) provides images of fluorescent objects at an enhanced resolution greater than that of conventional epifluorescence wide-field microscopy. Initially demonstrated in 1999 to enhance the lateral…

Optics · Physics 2022-03-09 James D. Manton

Scanning Electron Microscopy (SEM) is pivotal in revealing intricate micro- and nanoscale features across various research fields. However, obtaining high-resolution SEM images presents challenges, including prolonged scanning durations and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Tom Reclik , Setareh Medghalchi , Philipp Schumacher , Maximilian Wollenweber , Talal Al-Samman , Sandra Korte-Kerzel , Ulrich Kerzel

Properties of quantum states have disclosed new and revolutionary technologies, ranging from quantum information to quantum imaging. This last field is addressed to overcome limits of classical imaging by exploiting specific properties of…

Quantum Physics · Physics 2015-05-19 Giorgio Brida , Marco Genovese , Alice Meda , Ivano Ruo Berchera

Superresolution fluorescence microscopy techniques beat the diffraction limit, enabling ultra-high resolution imaging in biological physics and nanoscience. In all cases that have been studied experimentally, the resolution scales inversely…

Optics · Physics 2012-10-10 Alexander Small

In Super-resolution, a varying-illumination image stack is required. This enriched the dataset typically necessitates precise mechanical control and micron scale optical alignment and repeatability. Here, we introduce a novel methodology…

Multi-photon interference is at the heart of photonic quantum technologies. Arrays of integrated cavities can support bright sources of single-photons with high purity and small footprint, but the inevitable spectral distinguishability…

In the last years the possibility of creating and manipulating quantum states of light has paved the way to the development of new technologies exploiting peculiar properties of quantum states, as quantum information, quantum metrology &…

Quantum Physics · Physics 2016-06-17 Marco Genovese

Classical imaging works by scattering photons from an object to be imaged, and achieves resolution scaling as $1/\sqrt{t}$, with $t$ the imaging time. By contrast, the laws of quantum mechanics allow one to utilize quantum coherence to…

Recent advances in engineering and control of nanoscale quantum sensors have opened new paradigms in precision metrology. Unfortunately, hardware restrictions often limit the sensor performance. In nanoscale magnetic resonance probes, for…

Quantum Physics · Physics 2017-07-05 A. Ajoy , Y. X. Liu , K. Saha , L. Marseglia , J. -C. Jaskula , U. Bissbort , P. Cappellaro

We report the experimental realization of a quantum silicon carbide microscope (QSiCM) and demonstrate its functionality by imaging magnetic fields generated by electrical currents. We employ a dual-frequency sensing protocol to enhance the…

Quantum Physics · Physics 2025-09-19 A. Suhana , T. A. U. Svetikova , C. Schneider , M. Helm , A. N. Anisimov , G. V. Astakhov

The quantum statistical fluctuations of the electromagnetic field establish a limit, known as the shot-noise limit, on the sensitivity of optical measurements performed with classical technologies. However, quantum technologies are not…

High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

Image and Video Processing · Electrical Eng. & Systems 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

Quantum correlation of two-photon states has been utilized to suppress the environmental noise in imaging down to the single-photon level. However, the size of the coherence area of photon pairs limits the applications of quantum imaging…

Quantum Physics · Physics 2023-06-01 Dianzhen Cui , X. X. Yi , Li-Ping Yang

Stimulated Raman scattering (SRS) microscopy is a powerful label-free imaging technique that probes the vibrational response of chemicals with high specificity and sensitivity. High-power, quantum-enhanced SRS microscopes have been recently…

Quantum interferometry methods exploit quantum resources, such as photonic entanglement, to enhance phase estimation beyond classical limits. Nonlinear optics has served as a workhorse for the generation of entangled photon pairs, ensuring…

Quantum Physics · Physics 2025-08-04 Romain Dalidet , Anthony Martin , Grégory Sauder , Laurent Labonté , Sébastien Tanzilli

Motivated by the importance of optical microscopes to science and engineering, scientists have pondered for centuries how to improve their resolution and the existence of fundamental resolution limits. In recent years, a new class of…

Quantum Physics · Physics 2015-07-28 Mankei Tsang

Quantum sensing using non-linear interferometers offers the possibility of bicolour imaging, using light that never interacted with the object of interest, and provides a way to achieve phase supersensitivity, i.e. a Heisenberg-type scaling…

Quantum Physics · Physics 2024-04-22 Simon Schaffrath , Daniel Derr , Markus Gräfe , Enno Giese