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Proteins are miniature machines whose function depends on their three-dimensional (3D) structure. Determining this structure computationally remains an unsolved grand challenge. A major bottleneck involves selecting the most accurate…

Quantitative Methods · Quantitative Biology 2020-11-30 Stephan Eismann , Patricia Suriana , Bowen Jing , Raphael J. L. Townshend , Ron O. Dror

Capsule Networks have emerged as a powerful class of deep learning architectures, known for robust performance with relatively few parameters compared to Convolutional Neural Networks (CNNs). However, their inherent efficiency is often…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Miles Everett , Mingjun Zhong , Georgios Leontidis

We introduce a deep recurrent neural network architecture that approximates visual cortical circuits. We show that this architecture, which we refer to as the gamma-net, learns to solve contour detection tasks with better sample efficiency…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Drew Linsley , Junkyung Kim , Alekh Ashok , Thomas Serre

Capsule Network is a promising concept in deep learning, yet its true potential is not fully realized thus far, providing sub-par performance on several key benchmark datasets with complex data. Drawing intuition from the success achieved…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Jathushan Rajasegaran , Vinoj Jayasundara , Sandaru Jayasekara , Hirunima Jayasekara , Suranga Seneviratne , Ranga Rodrigo

Graph Convolutional Neural Networks (GCNNs) are the most recent exciting advancement in deep learning field and their applications are quickly spreading in multi-cross-domains including bioinformatics, chemoinformatics, social networks,…

Machine Learning · Statistics 2018-08-28 Saurabh Verma , Zhi-Li Zhang

Past few years have witnessed exponential growth of interest in deep learning methodologies with rapidly improving accuracies and reduced computational complexity. In particular, architectures using Convolutional Neural Networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Sai Samarth R Phaye , Apoorva Sikka , Abhinav Dhall , Deepti Bathula

The generation of protein crystals is necessary for the study of protein molecular function and structure. This is done empirically by processing large numbers of crystallization trials and inspecting them regularly in search of those with…

Computer Vision and Pattern Recognition · Computer Science 2018-05-15 Soheil Ghafurian , Peter Orth , Corey Strickland , Hua Su , Sangita Patel , Steven Soisson , Belma Dogdas

Machine learning based methods achieves impressive results in object classification and detection. Utilizing representative data of the visual world during the training phase is crucial to achieve good performance with such data driven…

Computer Vision and Pattern Recognition · Computer Science 2022-02-28 Bruno Ferrarini , Shoaib Ehsan , Adrien Bartoli , Aleš Leonardis , Klaus D. McDonald-Maier

Capsule networks are a class of neural networks that achieved promising results on many computer vision tasks. However, baseline capsule networks have failed to reach state-of-the-art results on more complex datasets due to the high…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Josef Gugglberger , David Peer , Antonio Rodríguez-Sánchez

Uncertainty estimation is essential for robust decision-making in the presence of ambiguous or out-of-distribution inputs. Gaussian Processes (GPs) are classical kernel-based models that offer principled uncertainty quantification and…

Machine Learning · Statistics 2026-04-30 Albert Saiapin , Kim Batselier

Introduction: The extracellular matrix (ECM) is a networkof proteins and carbohydrates that has a structural and bio-chemical function. The ECM plays an important role in dif-ferentiation, migration and signaling. Several studies…

Quantitative Methods · Quantitative Biology 2022-02-17 Mohamed Ghafoor , Anh Nguyen

Lung diseases including infections such as Pneumonia, Tuberculosis, and novel Coronavirus (COVID-19), together with Lung Cancer are significantly widespread and are, typically, considered life threatening. In particular, lung cancer is…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Parnian Afshar , Farnoosh Naderkhani , Anastasia Oikonomou , Moezedin Javad Rafiee , Arash Mohammadi , Konstantinos N. Plataniotis

We propose Masked Capsule Autoencoders (MCAE), the first Capsule Network that utilises pretraining in a modern self-supervised paradigm, specifically the masked image modelling framework. Capsule Networks have emerged as a powerful…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Miles Everett , Mingjun Zhong , Georgios Leontidis

This paper proposes a deep learning approach for traffic flow prediction in complex road networks. Traffic flow data from induction loop sensors are essentially a time series, which is also spatially related to traffic in different road…

Computer Vision and Pattern Recognition · Computer Science 2018-09-24 Youngjoo Kim , Peng Wang , Yifei Zhu , Lyudmila Mihaylova

Although Gaussian processes (GPs) with deep kernels have been successfully used for meta-learning in regression tasks, its uncertainty estimation performance can be poor. We propose a meta-learning method for calibrating deep kernel GPs for…

Machine Learning · Statistics 2023-12-14 Tomoharu Iwata , Atsutoshi Kumagai

Prediction of binding sites for transcription factors is important to understand how they regulate gene expression and how this regulation can be modulated for therapeutic purposes. Although in the past few years there are significant works…

Genomics · Quantitative Biology 2023-12-29 Nimisha Ghosh , Daniele Santoni , Indrajit Saha , Giovanni Felici

Prediction and discovery of new materials with desired properties are at the forefront of quantum science and technology research. A major bottleneck in this field is the computational resources and time complexity related to finding new…

Despite the remarkable success of the end-to-end paradigm in deep learning, it often suffers from slow convergence and heavy reliance on large-scale datasets, which fundamentally limits its efficiency and applicability in data-scarce…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Feifei Zhang , Zhenhong Jia , Sensen Song , Fei Shi , Dayong Ren

Brain tumor is considered as one of the deadliest and most common form of cancer both in children and in adults. Consequently, determining the correct type of brain tumor in early stages is of significant importance to devise a precise…

Computer Vision and Pattern Recognition · Computer Science 2018-03-05 Parnian Afshar , Arash Mohammadi , Konstantinos N. Plataniotis

Capsule Networks (CapsNets) are brand-new architectures that have shown ground-breaking results in certain areas of Computer Vision (CV). In 2017, Hinton and his team introduced CapsNets with routing-by-agreement in "Sabour et al" and in a…

Computer Vision and Pattern Recognition · Computer Science 2020-08-03 Moein Hasani , Amin Nasim Saravi , Hassan Khotanlou