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Quantitative photoacoustic tomography (QPAT) is a recent hybrid imaging modality that couples optical tomography with ultrasound imaging to achieve high resolution imaging of optical properties of scattering media. Image reconstruction in…

Analysis of PDEs · Mathematics 2015-09-02 Tian Ding , Kui Ren , Sarah Vallelian

Two-photon absorption photoacoustic tomography (TP-PAT) is a recent hybrid imaging modality that aims at reconstructing two-photon absorption properties of heterogeneous media from measured ultrasound signals generated by the photoacoustic…

Medical Physics · Physics 2018-03-14 Patrick Bardsley , Kui Ren , Rongting Zhang

We present a new nonlinear optimization approach for the sparse reconstruction of single-photon absorption and two-photon absorption coefficients in photoacoustic tomography (PAT). This framework comprises of minimizing an objective…

Optimization and Control · Mathematics 2020-06-30 Madhu Gupta , Rohit Kumar Mishra , Souvik Roy

In this paper, we describe the numerical reconstruction method for quantitative photoacoustic tomography (QPAT) based on the radiative transfer equation (RTE), which models light propagation more accurately than diffusion approximation…

Quantitative Methods · Quantitative Biology 2017-10-25 Chao Wang , Tie Zhou

To obtain the initial pressure from the collected data on a planar sensor arrangement in Photoacoustic tomography, there exists an exact analytic frequency domain reconstruction formula. An efficient realization of this formula needs to…

Numerical Analysis · Mathematics 2015-01-14 Julian Schmid , Thomas Glatz , Behrooz Zabihian , Mengyang Liu , Wolfgang Drexler , Otmar Scherzer

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

We investigate a hybrid inverse problem in fluorescence ultrasound modulated optical tomography (fUMOT) in the diffusive regime. We prove that the absorption coefficient of the fluorophores at the excitation frequency and the quantum…

Analysis of PDEs · Mathematics 2018-04-05 Wei Li , Yang Yang , Yimin Zhong

Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in…

Numerical Analysis · Mathematics 2016-12-21 Simon Arridge , Paul Beard , Marta Betcke , Ben Cox , Nam Huynh , Felix Lucka , Olumide Ogunlade , Edward Zhang

We propose a combined reconstruction-classification method for simultaneously recovering absorption and scattering in turbid media from images of absorbed optical energy. This method exploits knowledge that optical parameters are determined…

Medical Physics · Physics 2016-01-20 Emma Malone , Samuel Powell , Ben T. Cox , Simon R. Arridge

Fourier ptychographic microscopy (FPM) is a pivotal computational imaging technique that achieves phase and amplitude reconstruction with high resolution and wide field of view, using low numerical aperture objectives and LED array…

Inspired by the recent advances on minimizing nonsmooth or bound-constrained convex functions on models using varying degrees of fidelity, we propose a line search multigrid (MG) method for full-wave iterative image reconstruction in…

Numerical Analysis · Mathematics 2016-11-22 Ashkan Javaherian , Sean Holman

Fluorescence photoacoustic tomography (fPAT) is a molecular imaging modality that combines photoacoustic tomography (PAT) with fluorescence imaging to obtain high-resolution imaging of fluorescence distributions inside heterogeneous media.…

Analysis of PDEs · Mathematics 2019-09-27 Kui Ren , Rongting Zhang , Yimin Zhong

In this paper we propose an approach for \emph{simultaneous} identification of the \emph{absorption density} and the \emph{speed of sound} by photoacoustic measurements. Experimentally our approach can be realized with sliced photoacoustic…

Analysis of PDEs · Mathematics 2011-09-28 Andreas Kirsch , Otmar Scherzer

We propose a model-based image reconstruction method for photoacoustic tomography(PAT) involving a novel form of regularization and demonstrate its ability to recover good quality images from significantly reduced size datasets. The…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Nadaparambil Aravindakshan Rejesh , Sandeep Kumar Kalva , Manojit Pramanik , Muthuvel Arigovindan

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging technique that holds great promise for biomedical imaging. PACT is a hybrid imaging method that can exploit the strong endogenous…

Medical Physics · Physics 2019-05-13 Joemini Poudel , Yang Lou , Mark A. Anastasio

Photoacoustic tomography (PAT) is a hybrid imaging modality that intends to construct high-resolution images of optical properties of heterogeneous media from measured acoustic data generated by the photoacoustic effect. To date, most of…

Numerical Analysis · Mathematics 2019-08-07 Christina Frederick , Kui Ren , Sarah Vallélian

Photo-acoustic tomography is a newly developed hybrid imaging modality that combines a high-resolution modality with a high-contrast modality. We analyze the reconstruction of diffusion and absorption parameters in an elliptic equation and…

Analysis of PDEs · Mathematics 2015-06-04 Jie Chen , Yang Yang

Compressed sensing fluorescence microscopy (CS-FM) proposes a scheme whereby less measurements are collected during sensing and reconstruction is performed to recover the image. Much work has gone into optimizing the sensing and…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Alan Q. Wang , Aaron K. LaViolette , Leo Moon , Chris Xu , Mert R. Sabuncu

Spectral domain optical coherence tomography (OCT) offers high resolution multidimensional imaging, but generally suffers from defocussing, intensity falloff and shot noise, causing artifacts and image degradation along the imaging depth.…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Jonathan H. Mason , Yvonne Reinwald , Ying Yang , Sarah Waters , Alicia El Haj , Pierre O. Bagnaninchi
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