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The efficiency of exact simulation methods for the reaction-diffusion master equation (RDME) is severely limited by the large number of diffusion events if the mesh is fine or if diffusion constants are large. Furthermore, inherent…

Numerical Analysis · Computer Science 2015-06-15 Andreas Hellander , Michael Lawson , Brian Drawert , Linda Petzold

To date, the simulation of organ deformations for applications like therapy planning or image-guided interventions is calculated by solving the elastodynamics equations. While efficient solvers have been proposed for fast simulations,…

Quantitative Methods · Quantitative Biology 2018-12-18 Felix Meister , Tiziano Passerini , Viorel Mihalef , Ahmet Tuysuzoglu , Andreas Maier , Tommaso Mansi

Quantization has proven effective in high-resolution and large-scale simulations, which benefit from bit-level memory saving. However, identifying a quantization scheme that meets the requirement of both precision and memory efficiency…

Graphics · Computer Science 2022-07-15 Jiafeng Liu , Haoyang Shi , Siyuan Zhang , Yin Yang , Chongyang Ma , Weiwei Xu

Neuronal damage, in the form of both brain and spinal cord injuries, is one of the major causes of disability and death in young adults worldwide. One way to assess the direct damage occurring after a mechanical insult is the simulation of…

Neural and Evolutionary Computing · Computer Science 2024-09-20 Antonio LaTorre , Man Ting Kwong , Julián A. García-Grajales , Riyi Shi , Antoine Jérusalem , José-María Peña

We present a novel approach for high-order accurate numerical differentiation on unstructured meshes of quadrilateral elements. To differentiate a given function, an auxiliary function with greater smoothness properties is defined which…

Numerical Analysis · Mathematics 2022-05-11 Yulong Pan , Per-Olof Persson

Based on the work of Xu and Zhou [Math.Comput., 69(2000), pp.881-909], we establish new three-level and multilevel finite element discretizations by local defect-correction technique. Theoretical analysis and numerical experiments show that…

Numerical Analysis · Mathematics 2023-07-19 Yidu Yang , Jiayu Han

Closure problems are omnipresent when simulating multiscale systems, where some quantities and processes cannot be fully prescribed despite their effects on the simulation's accuracy. Recently, scientific machine learning approaches have…

Numerical Analysis · Mathematics 2024-09-13 Benjamin Sanderse , Panos Stinis , Romit Maulik , Shady E. Ahmed

The present report describes a big data numerical study of crystal plasticity finite element (CPFE) modelling using static and grain-based meshing to investigate the dependence of the results on the discretization approach. Static mesh…

Materials Science · Physics 2023-02-01 Jingwei Chen , Zifan Wang , Alexander M. Korsunsky

Diffusion probabilistic models (DPMs) have achieved impressive success in visual generation. While, they suffer from slow inference speed due to iterative sampling. Employing fewer sampling steps is an intuitive solution, but this will also…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Hu Yu , Hao Luo , Fan Wang , Feng Zhao

State-of-the-art Deep Neural Networks can be easily fooled into providing incorrect high-confidence predictions for images with small amounts of adversarial noise. Does this expose a flaw with deep neural networks, or do we simply need a…

Computer Vision and Pattern Recognition · Computer Science 2017-07-25 Akshayvarun Subramanya , Suraj Srinivas , R. Venkatesh Babu

We introduce the technique of adaptive discretization to design an efficient model-based episodic reinforcement learning algorithm in large (potentially continuous) state-action spaces. Our algorithm is based on optimistic one-step value…

Machine Learning · Computer Science 2020-10-26 Sean R. Sinclair , Tianyu Wang , Gauri Jain , Siddhartha Banerjee , Christina Lee Yu

The discretization of fluid-poromechanics systems is typically highly demanding in terms of computational effort. This is particularly true for models of multiphysics flows in the brain, due to the geometrical complexity of the cerebral…

Numerical Analysis · Mathematics 2024-07-16 Ivan Fumagalli , Nicola Parolini , Marco Verani

We develop a novel Hybrid High-Order method for the simulation of Darcy flows in fractured porous media. The discretization hinges on a mixed formulation in the bulk region and on a primal formulation inside the fracture. Salient features…

Numerical Analysis · Mathematics 2017-12-01 Florent Chave , Daniele Di Pietro , Luca Formaggia

In the empirical study of evolutionary algorithms, the solution quality is evaluated by either the fitness value or approximation error. The latter measures the fitness difference between an approximation solution and the optimal solution.…

Neural and Evolutionary Computing · Computer Science 2018-10-30 Jun He , Yu Chen , Yuren Zhou

The numerical simulation of the diffusion MRI signal arising from complex tissue micro-structures is helpful for understanding and interpreting imaging data as well as for designing and optimizing MRI sequences. The discretization of the…

Computational Engineering, Finance, and Science · Computer Science 2019-10-23 Van-Dang Nguyen , Massimiliano Leoni , Tamara Dancheva , Johan Jansson , Johan Hoffman , Demian Wassermann , Jing-Rebecca Li

Unfitted (also known as embedded or immersed) finite element approximations of partial differential equations are very attractive because they have much lower geometrical requirements than standard body-fitted formulations. These schemes do…

Numerical Analysis · Mathematics 2022-04-13 Santiago Badia , Pere A. Martorell , Francesc Verdugo

Robotic cutting of soft materials is critical for applications such as food processing, household automation, and surgical manipulation. As in other areas of robotics, simulators can facilitate controller verification, policy learning, and…

Robotics · Computer Science 2021-05-27 Eric Heiden , Miles Macklin , Yashraj Narang , Dieter Fox , Animesh Garg , Fabio Ramos

Accurately solving PDEs with localised features requires refined meshes that adapt to the solution. Traditional numerical methods, such as finite elements, are linear in nature and often ineffective for such problems, as the mesh is not…

Numerical Analysis · Mathematics 2025-08-27 Alexandre Magueresse , Santiago Badia

The use of deep learning for medical imaging has seen tremendous growth in the research community. One reason for the slow uptake of these systems in the clinical setting is that they are complex, opaque and tend to fail silently. Outside…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Terrance DeVries , Graham W. Taylor

This paper presents a new Bayesian framework for quantifying discretization errors in numerical solutions of ordinary differential equations. By modelling the errors as random variables, we impose a monotonicity constraint on the variances,…

Numerical Analysis · Mathematics 2024-11-14 Yuto Miyatake , Kaoru Irie , Takeru Matsuda