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Purpose: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is correlated with increased morbidity and mortality. It is associated with atrial fibrosis, which may be assessed non-invasively using late gadolinium-enhanced…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Guang Yang , Xiahai Zhuang , Habib Khan , Shouvik Haldar , Eva Nyktari , Lei Li , Rick Wage , Xujiong Ye , Greg Slabaugh , Raad Mohiaddin , Tom Wong , Jennifer Keegan , David Firmin

Pulsed field ablation (PFA) has emerged as a non-thermal alternative to traditional thermal ablation techniques for the treatment of atrial fibrillation (AF). This study presents a patient-specific 3D computational framework to model the…

Medical Physics · Physics 2025-08-12 Ashkan Bagherzadeh , Nagib T Chalfoun , Tong Gao , Lik Chuan Lee

Late gadolinium enhancement magnetic resonance imaging (LGE MRI) is commonly used to visualize and quantify left atrial (LA) scars. The position and extent of scars provide important information of the pathophysiology and progression of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-11 Lei Li , Veronika A. Zimmer , Julia A. Schnabel , Xiahai Zhuang

Catheter ablation of Atrial Fibrillation (AF) consists of a one-size-fits-all treatment with limited success in persistent AF. This may be due to our inability to map the dynamics of AF with the limited resolution and coverage provided by…

Late Gadolinium Enhancement Magnetic Resonance Imaging (LGE MRI) emerged as a routine scan for patients with atrial fibrillation (AF). However, due to the low image quality automating the quantification and analysis of the atrial scars is…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Lei Li , Fuping Wu , Guang Yang , Tom Wong , Raad Mohiaddin , David Firmin , Jenny Keegan , Lingchao Xu , Xiahai Zhuang

Atrial Fibrillation (AF) is characterized by disorganised electrical activity in the atria and is known to be sustained by the presence of regions of fibrosis (scars) or functional cellular remodeling, both of which may lead to areas of…

Late gadolinium enhancement magnetic resonance imaging (LGE MRI) appears to be a promising alternative for scar assessment in patients with atrial fibrillation (AF). Automating the quantification and analysis of atrial scars can be…

Computer Vision and Pattern Recognition · Computer Science 2019-02-22 Lei Li , Fuping Wu , Guang Yang , Lingchao Xu , Tom Wong , Raad Mohiaddin , David Firmin , Jennifer Keegan , Xiahai Zhuang

Catheter based radiofrequency ablation for pulmonary vein isolation has become the first line of treatment for atrial fibrillation in recent years. This requires a rather accurate map of the left atrial sub-endocardial surface including the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Alon Baram , Moshe Safran , Tomer Noy , Naveh Geri , Hayit Greenspan

Left atrial voltage maps are routinely acquired during electroanatomic mapping in patients undergoing catheter ablation for atrial fibrillation. For patients, who have prior catheter ablation when they are in sinus rhythm, the voltage map…

Medical Physics · Physics 2022-11-10 Jiyue He , Kuk Jin Jang , Katie Walsh , Jackson Liang , Sanjay Dixit , Rahul Mangharam

Mitral valve regurgitation is the most common valvular disease, affecting 10% of the population over 75 years old. Left untreated, patients with mitral valve regurgitation can suffer declining cardiac health until cardiac failure and death.…

Image and Video Processing · Electrical Eng. & Systems 2019-06-13 Patrick Carnahan , Olivia Ginty , John Moore , Andras Lasso , Matthew A. Jolley , Christian Herz , Mehdi Eskandari , Daniel Bainbridge , Terry M. Peters

Pulmonary embolism (PE) is a highly mortal disease, currently assessed by pulmonary CT angiography. True-FISP MRI has emerged as an innocuous alternative that does not hold many of the limitations of x-ray imaging. However, True-FISP MRI is…

Computer Vision and Pattern Recognition · Computer Science 2017-09-26 Luis R Soenksen , Luis Jiménez-Angeles , Gabriela Melendez , Aloha Meave

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Accurate segmentation of the left atrial (LA) and LA scars can provide valuable information to predict treatment outcomes in AF. In this paper, we proposed to automatically…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Yuchen Zhang , Yanda Meng , Yalin Zheng

Atrial fibrillation is one of the most frequent cardiac arrhythmias in the industrialized world and ablation therapy is the method of choice for many patients. However, ablation scars alter the electrophysiological activation and the…

Biological Physics · Physics 2022-04-21 Tobias Gerach , Steffen Schuler , Andreas Wachter , Axel Loewe

Three-dimensional late gadolinium enhanced (LGE) cardiac MR (CMR) of left atrial scar in patients with atrial fibrillation (AF) has recently emerged as a promising technique to stratify patients, to guide ablation therapy and to predict…

Image and Video Processing · Electrical Eng. & Systems 2020-02-04 Guang Yang , Jun Chen , Zhifan Gao , Shuo Li , Hao Ni , Elsa Angelini , Tom Wong , Raad Mohiaddin , Eva Nyktari , Ricardo Wage , Lei Xu , Yanping Zhang , Xiuquan Du , Heye Zhang , David Firmin , Jennifer Keegan

Recently, machine learning has been successfully applied to model-based left ventricle (LV) segmentation. The general framework involves two stages, which starts with LV localization and is followed by boundary delineation. Both are driven…

Computer Vision and Pattern Recognition · Computer Science 2015-07-29 Peng Sun , Haoyin Zhou , Devon Lundine , James K. Min , Guanglei Xiong

Segmentation of the left ventricle in cardiac magnetic resonance imaging MRI scans enables cardiologists to calculate the volume of the left ventricle and subsequently its ejection fraction. The ejection fraction is a measurement that…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Garvit Chhabra , J. H. Gagan , J. R. Harish Kumar

Anatomical and biophysical modeling of left atrium (LA) and proximal pulmonary veins (PPVs) is important for clinical management of several cardiac diseases. Magnetic resonance imaging (MRI) allows qualitative assessment of LA and PPVs…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Aliasghar Mortazi , Rashed Karim , Kawal Rhode , Jeremy Burt , Ulas Bagci

Background: Ventilator-associated pneumonia (VAP) in traumatic brain injury (TBI) patients poses a significant mortality risk and imposes a considerable financial burden on patients and healthcare systems. Timely detection and…

Machine Learning · Computer Science 2024-08-05 Negin Ashrafi , Armin Abdollahi , Maryam Pishgar

With the development of medical computer-aided diagnostic systems, pulmonary artery-vein(A/V) separation plays a crucial role in assisting doctors in preoperative planning for lung cancer surgery. However, distinguishing arterial from…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Lin Pan , Yaoyong Zheng , Liqin Huang , Liuqing Chen , Zhen Zhang , Rongda Fu , Bin Zheng , Shaohua Zheng

Atrial fibrillation (AF) represents the most prevalent type of cardiac arrhythmia for which treatment may require patients to undergo ablation therapy. In this surgery cardiac tissues are locally scarred on purpose to prevent electrical…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Franz Thaler , Darko Stern , Gernot Plank , Martin Urschler
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