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Shape transformations of epithelial tissues in three dimensions, which are crucial for embryonic development or in vitro organoid growth, can result from active forces generated within the cytoskeleton of the epithelial cells. How the…

Biological Physics · Physics 2024-12-23 Diana Khoromskaia , Guillaume Salbreux

We consider diffeomorphisms of compact Riemmanian manifolds which have a Gibbs-Markov-Young structures, consisting of a reference set $\Lambda$ with a hyperbolic product structure and a countable Markov partition. We assume polynomial…

Dynamical Systems · Mathematics 2013-12-06 Jose F. Alves , Davide Azevedo

In this paper we derive a model to describe the important inelastic features associated with the cyclic softening, often referred to as stress-softening, of soft biological tissue. The model developed here includes the notion of multiple…

Soft Condensed Matter · Physics 2020-05-19 Stephen R. Rickaby , Nigel H. Scott

We present here a population structured model to describe the dynamics of macrophage cells. The model involves the interactions between modified LDL, monocytes/macrophages, cytokines and foam cells. The key assumption is that the individual…

Analysis of PDEs · Mathematics 2017-03-31 Nicolas Meunier , Nicolas Muller

Multidimensional systems coupled via complex networks are widespread in nature and thus frequently invoked for a large plethora of interesting applications. From ecology to physics, individual entities in mutual interactions are grouped in…

Physics and Society · Physics 2018-11-21 Giulia Cencetti , Franco Bagnoli , Giorgio Battistelli , Luigi Chisci , Duccio Fanelli

Roots provide basic functions to plants such as water/nutrient uptake and anchoring in soil. The growth and development of root systems contribute to colonizing the surrounding soil and optimizing the access to resources. It is usually…

Soft Condensed Matter · Physics 2019-04-24 M. Fakih , J. -Y. Delenne , F. Radjai , T. Fourcaud

The Abelian Sandpile Model is a cellular automaton whose discrete dynamics reaches an out-of-equilibrium steady state resembling avalanches in piles of sand. The fundamental moves defining the dynamics are encoded by the toppling rules. The…

Statistical Mechanics · Physics 2012-09-25 Sergio Caracciolo , Guglielmo Paoletti , Andrea Sportiello

We study a mathematical model describing the dynamics of a pluripotent stem cell population involved in the blood production process in the bone marrow. This model is a differential equation with a time delay. The delay describes the cell…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Shigui Ruan

A number of factors, such as, cell-cell interactions and self-propulsion of cells driven by cytoskeletal forces determine tissue morphologies and dynamics. To explore the interplay between these factors in controlling the dynamics at the…

Soft Condensed Matter · Physics 2025-05-12 Rajsekhar Das , Xin Li , Sumit Sinha , D. Thirumalai

A system of replicators with Hebbian random couplings is studied using dynamical methods. The self-reproducing species are here characterized by a set of binary traits and interact based on complementarity. In the case of an extensive…

Disordered Systems and Neural Networks · Physics 2009-11-11 Tobias Galla

Morphogenesis depends crucially on the complex rheological properties of cell tissues and on their ability to maintain mechanical integrity while rearranging at long times. In this paper, we study the rheology of polygonal cellular networks…

Soft Condensed Matter · Physics 2021-03-31 Charlie Duclut , Joris Paijmans , Mandar M. Inamdar , Carl D. Modes , Frank Jülicher

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michele Bezzi , Andrea Ciliberto

Amoeboid cell motility is essential for a wide range of biological processes including wound healing, embryonic morphogenesis, and cancer metastasis. It relies on complex dynamical patterns of cell shape changes that pose long-standing…

The mechanical properties of tissues play an essential role for all tissue properties such as cell division, and differentiation or morphogenesis. Here, we study theoretically the rheology of 2-dimensional epithelial tissues described by a…

Soft Condensed Matter · Physics 2023-12-18 Doron Grossman , Jean-Francois Joanny

Topology optimization of microstructures plays a critical role in optimizing functional performance across diverse engineering applications. While metamaterials with enhanced mechanical properties -- such as hyperelasticity, energy…

Soft Condensed Matter · Physics 2025-01-27 Weiming Wang , Yanhao Hou , Renbo Su , Weiguang Wang , Charlie C. L. Wang

Cellular self-assembly and organization are fundamental steps for the development of biological tissues. In this paper, within the framework of a cellular automata model, we address how an ordered tissue pattern spontaneously emerges from a…

Biological Physics · Physics 2019-10-24 Debangana Mukhopadhyay , Rumi De

Cell growth, division and death are defining features of biological tissues that contribute to morphogenesis. In hydrodynamic descriptions of cohesive tissues, their occurrence implies a non-zero rate of variation of cell density. We show…

Tissues and Organs · Quantitative Biology 2017-08-23 Shunsuke Yabunaka , Philippe Marcq

We present a model of adaptive regulatory networks consisting of a simple biologically-motivated rewiring procedure coupled to an elementary stability criterion. The resulting networks exhibit a characteristic stationary heavy-tailed degree…

Physics and Society · Physics 2020-08-05 Ben D. MacArthur , Rubén J. Sánchez-García , Avi Ma'ayan

In this paper, we analyze the dynamics of spreading processes taking place over time-varying networks. A common approach to model time-varying networks is via Markovian random graph processes. This modeling approach presents the following…

Social and Information Networks · Computer Science 2016-11-04 Masaki Ogura , Victor M. Preciado

Active emulsions and liquid crystalline shells are intriguing and experimentally realisable types of topological matter. Here we numerically study the morphology and spatiotemporal dynamics of a double emulsion, where one or two passive…

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