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The reproduction and replication of research results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the challenges closely revolve around…

Software Engineering · Computer Science 2017-07-31 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

Reproducibility of computational research is critical for ensuring transparency, reliability and reusability. Challenges with computational reproducibility have been documented in several fields, but healthcare discrete-event simulation…

Other Quantitative Biology · Quantitative Biology 2025-09-17 Amy Heather , Thomas Monks , Alison Harper , Navonil Mustafee , Andrew Mayne

The process of painting fosters creativity and rational planning. However, existing generative AI mostly focuses on producing visually pleasant artworks, without emphasizing the painting process. We introduce a novel task, Collaborative…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Nicola Dall'Asen , Willi Menapace , Elia Peruzzo , Enver Sangineto , Yiming Wang , Elisa Ricci

Recent studies have shown that the majority of published computational models in systems biology and physiology are not repeatable or reproducible. There are a variety of reasons for this. One of the most likely reasons is that given how…

Other Quantitative Biology · Quantitative Biology 2021-07-13 Herbert M. Sauro

Being able to duplicate published research results is an important process of conducting research whether to build upon these findings or to compare with them. This process is called "replicability" when using the original authors'…

Digital Libraries · Computer Science 2020-05-07 Nicolas Bonneel , David Coeurjolly , Julie Digne , Nicolas Mellado

Reproducibility is a fundamental requirement of the scientific process since it enables outcomes to be replicated and verified. Computational scientific experiments can benefit from improved reproducibility for many reasons, including…

Databases · Computer Science 2019-09-04 Maria Luiza Mondelli , A. Townsend Peterson , Luiz M. R. Gadelha

Computational physics increasingly depends on large simulation datasets generated by software that remains under active development for many years. In such settings, reproducibility requires not only well documented data but also explicit…

Computational Physics · Physics 2026-04-30 Markus Uehlein , Tobias Held , Christopher Seibel , Lukas G. Jonda , Baerbel Rethfeld , Sebastian T. Weber

A key challenge in deriving unified neural solvers for combinatorial optimization (CO) is efficient generalization of models between a given set of tasks to new tasks not used during the initial training process. To address it, we first…

Machine Learning · Computer Science 2026-03-04 Semih Cantürk , Thomas Sabourin , Frederik Wenkel , Michael Perlmutter , Guy Wolf

We present Clinica (www.clinica.run), an open-source software platform designed to make clinical neuroscience studies easier and more reproducible. Clinica aims for researchers to i) spend less time on data management and processing, ii)…

This tutorial covers biomedical image reconstruction, from the foundational concepts of system modeling and direct reconstruction to modern sparsity and learning-based approaches. Imaging is a critical tool in biological research and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Michael T. McCann , Michael Unser

The reproduction and replication of reported scientific results is a hot topic within the academic community. The retraction of numerous studies from a wide range of disciplines, from climate science to bioscience, has drawn the focus of…

Computational Engineering, Finance, and Science · Computer Science 2014-10-15 Tom Crick , Benjamin A. Hall , Samin Ishtiaq , Kenji Takeda

The high incidence of irreproducible research has led to urgent appeals for transparency and equitable practices in open science. For the scientific disciplines that rely on computationally intensive analyses of large data sets, a granular…

Although reproducibility is a core tenet of the scientific method, it remains challenging to reproduce many results. Surprisingly, this also holds true for computational results in domains such as systems biology where there have been…

Quantitative Methods · Quantitative Biology 2021-04-13 Michael L. Blinov , John H. Gennari , Jonathan R. Karr , Ion I. Moraru , David P. Nickerson , Herbert M. Sauro

Containers as the unit of application delivery are the 'next big thing' in the software development world. They enable developers to create an executable image containing an application bundled with all its dependencies which a user can run…

Software Engineering · Computer Science 2017-02-13 Jonas Weber

Computational reproducibility refers to obtaining consistent results when rerunning an experiment. Jupyter Notebook, a web-based computational notebook application, facilitates running, publishing, and sharing computational experiments…

Software Engineering · Computer Science 2025-09-30 A S M Shahadat Hossain , Colin Brown , David Koop , Tanu Malik

Many forms of programmable matter have been proposed for various tasks. We use an abstract model of self-organizing particle systems for programmable matter which could be used for a variety of applications, including smart paint and…

Emerging Technologies · Computer Science 2017-10-24 Alexandra Porter , Andréa W. Richa

Computational reproducibility, the possibility for independent researchers to exactly reproduce published empirical results, is fundamental to science. Despite its importance, the proportion of research articles aiming for reproducibility…

These lecture notes are designed to accompany an imaginary, virtual, undergraduate, one or two semester course on fundamentals of Parallel Computing as well as to serve as background and reference for graduate courses on High-Performance…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-02 Jesper Larsson Träff

Reproducibility of computationally-derived scientific discoveries should be a certainty. As the product of several person-years' worth of effort, results -- whether disseminated through academic journals, conferences or exploited through…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

Scientific research frequently involves the use of computational tools and methods. Providing thorough documentation, open-source code, and data -- the creation of reproducible computational research -- helps others understand a…

Digital Libraries · Computer Science 2022-09-14 Tim von Hahn , Chris K. Mechefske