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In biomedical research, repeated measurements within each subject are often processed to remove artifacts and unwanted sources of variation. The resulting data are used to construct derived outcomes that act as proxies for scientific…

Methodology · Statistics 2026-02-03 Zihang Wang , Razieh Nabi , Benjamin B. Risk

Changepoint detection is commonly formulated by minimizing the sum of in-sample losses to quantify the model's overall fit. However, for flexible modeling procedures -- especially those involving high-dimensional parameter spaces or…

Methodology · Statistics 2026-05-05 Chengde Qian , Guanghui Wang , Zhaojun Wang , Changliang Zou

Systems design processes are increasingly reliant on simulation models to inform design decisions. A pervasive issue within the systems engineering community is trusting in the models used to make decisions about complex systems. This work…

Computational Engineering, Finance, and Science · Computer Science 2025-08-05 Edward Louis , Gregory Mocko , Evan Taylor

Observational studies provide invaluable opportunities to draw causal inference, but they may suffer from biases due to pretreatment difference between treated and control units. Matching is a popular approach to reduce observed covariate…

Methodology · Statistics 2025-09-17 Xinran Li

The estimation of static parameters in dynamical systems and control theory has been extensively studied, with significant progress made in estimating varying parameters in specific system types. Suppose, in the general case, we have data…

Optimization and Control · Mathematics 2025-07-10 Jamiree Harrison , Enoch Yeung

We propose a new deep learning model for goal-driven tasks that require intuitive physical reasoning and intervention in the scene to achieve a desired end goal. Its modular structure is motivated by hypothesizing a sequence of intuitive…

Artificial Intelligence · Computer Science 2020-11-17 Augustin Harter , Andrew Melnik , Gaurav Kumar , Dhruv Agarwal , Animesh Garg , Helge Ritter

Modern language models can imitate complex patterns through few-shot learning, enabling them to complete challenging tasks without fine-tuning. However, imitation can also lead models to reproduce inaccuracies or harmful content if present…

Machine Learning · Computer Science 2024-03-13 Danny Halawi , Jean-Stanislas Denain , Jacob Steinhardt

We propose a novel training regime termed counterfactual training that leverages counterfactual explanations to increase the explanatory capacity of models. Counterfactual explanations have emerged as a popular post-hoc explanation method…

Machine Learning · Computer Science 2026-01-23 Patrick Altmeyer , Aleksander Buszydlik , Arie van Deursen , Cynthia C. S. Liem

Climate models exhibit an approximately invariant surface warming pattern in typical end-of-century projections. This observation has been used extensively in climate impact assessments for fast calculations of local temperature anomalies,…

Atmospheric and Oceanic Physics · Physics 2024-11-22 Paolo Giani , Arlene M. Fiore , Glenn Flierl , Raffaele Ferrari , Noelle E. Selin

The ubiquity of machine learning based predictive models in modern society naturally leads people to ask how trustworthy those models are? In predictive modeling, it is quite common to induce a trade-off between accuracy and…

Machine Learning · Computer Science 2019-04-05 John Mitros , Brian Mac Namee

Modern machine learning models are opaque, and as a result there is a burgeoning academic subfield on methods that explain these models' behavior. However, what is the precise goal of providing such explanations, and how can we demonstrate…

Machine Learning · Computer Science 2022-12-01 Patrick Fernandes , Marcos Treviso , Danish Pruthi , André F. T. Martins , Graham Neubig

Individuals use models to guide decisions, but many models are wrong. This paper studies which misspecified models are likely to persist when individuals also entertain alternative models. Consider an agent who uses her model to learn the…

Theoretical Economics · Economics 2023-08-22 Cuimin Ba

We redesigned an advanced physics laboratory course to include a project component. The intention was to address learning outcomes such as modeling, design of experiments, teamwork, and developing technical skills in using apparatus and…

Physics Education · Physics 2022-07-06 Bei Cai , Lindsay Mainhood , Robert G. Knobel

Neutron reflectometry analysis is an inherently ill-posed, which is to say that there are many possible solutions which agree equally well with the measured data. This leads to the application of model-dependent analysis, where information…

Applications · Statistics 2020-03-20 Andrew R. McCluskey

The overarching goal of this work is to efficiently enable end-users to correctly anticipate a robot's behavior in novel situations. Since a robot's behavior is often a direct result of its underlying objective function, our insight is that…

Robotics · Computer Science 2018-10-19 Sandy H. Huang , David Held , Pieter Abbeel , Anca D. Dragan

Scientists investigate the dynamics of complex systems with quantitative models, employing them to synthesize knowledge, to explain observations, and to forecast future system behavior. Complete specification of systems is impossible, so…

Quantitative Methods · Quantitative Biology 2007-05-23 S. R. Borrett , W. Bridewell , P. Langely , K. R. Arrigo

When neural networks are employed for high-stakes decision-making, it is desirable that they provide explanations for their prediction in order for us to understand the features that have contributed to the decision. At the same time, it is…

Machine Learning · Computer Science 2022-05-10 Penny Chong , Ngai-Man Cheung , Yuval Elovici , Alexander Binder

Using a time series model to mimic an observed time series has a long history. However, with regard to this objective, conventional estimation methods for discrete-time dynamical models are frequently found to be wanting. In fact, they are…

Statistics Theory · Mathematics 2015-03-19 Yingcun Xia , Howell Tong

Modeling biological processes is a highly demanding task because not all processes are fully understood. Mathematical models allow us to test hypotheses about possible mechanisms of biological processes. The mathematical mechanisms…

Numerical Analysis · Mathematics 2023-12-11 Cordula Reisch , Hannah Burmester

Causal discovery can be a powerful tool for investigating causality when a system can be observed but is inaccessible to experiments in practice. Despite this, it is rarely used in any scientific or medical fields. One of the major hurdles…

Machine Learning · Statistics 2019-10-07 Erich Kummerfeld , Alexander Rix