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Randomized clinical trials are considered the gold standard for estimating causal effects. Nevertheless, in studies that are aimed at examining adverse effects of interventions, such trials are often impractical because of ethical and…

Methodology · Statistics 2020-01-20 Anthony D. Scotina , Andrew R. Zullo , Robert J. Smith , Roee Gutman

In medical applications, deep learning methods are built to automate diagnostic tasks. However, a clinically relevant question that practitioners usually face, is how to predict the future trajectory of a disease (prognosis). Current…

Machine Learning · Computer Science 2021-12-08 Huy Hoang Nguyen , Simo Saarakkala , Matthew B. Blaschko , Aleksei Tiulpin

Prediction of diabetes and its various complications has been studied in a number of settings, but a comprehensive overview of problem setting for diabetes prediction and care management has not been addressed in the literature. In this…

Machine Learning · Computer Science 2021-04-30 Aloysius Lim , Ashish Singh , Jody Chiam , Carly Eckert , Vikas Kumar , Muhammad Aurangzeb Ahmad , Ankur Teredesai

Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce…

Machine Learning · Computer Science 2019-04-01 Neil C. Borle , Edmond A. Ryan , Russell Greiner

Recently, the wearable and non-invasive blood glucose estimation approach has been proposed. However, due to the unreliability of the acquisition device, the presence of the noise and the variations of the acquisition environments, the…

Medical Physics · Physics 2025-03-07 Yiting Wei , Bingo Wing-Kuen Ling , Danni Chen , Yuheng Dai , Qing Liu

Diabetes has emerged as a significant global health issue, especially with the increasing number of cases in many countries. This trend Underlines the need for a greater emphasis on early detection and proactive management to avert or…

Machine Learning · Computer Science 2025-06-16 Mowafaq Salem Alzboon , Muhyeeddin Alqaraleh , Mohammad Subhi Al-Batah

With the growing prevalence of diabetes and the associated public health burden, it is crucial to identify modifiable factors that could improve patients' glycemic control. In this work, we seek to examine associations between medication…

Applications · Statistics 2025-12-22 Alexander Coulter , Rashmi N. Aurora , Naresh M. Punjabi , Irina Gaynanova

We tackle the problem of forecasting network-signal snapshots using past signal measurements acquired by a subset of network nodes. This task can be seen as a combination of multivariate time-series prediction and graph-signal…

Signal Processing · Electrical Eng. & Systems 2020-06-03 Gabriela Lewenfus , Wallace Alves Martins , Symeon Chatzinotas , Björn Ottersten

Neural forecasting has shown significant improvements in the accuracy of large-scale systems, yet predicting extremely long horizons remains a challenging task. Two common problems are the volatility of the predictions and their…

Machine Learning · Computer Science 2021-06-11 Cristian Challu , Kin G. Olivares , Gus Welter , Artur Dubrawski

Future prediction is a fundamental principle of intelligence that helps plan actions and avoid possible dangers. As the future is uncertain to a large extent, modeling the uncertainty and multimodality of the future states is of great…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Osama Makansi , Eddy Ilg , Özgün Cicek , Thomas Brox

Continuous glucose monitoring (CGM) provides dense and dynamic glucose profiles that enable reliable estimation of Ambulatory Glucose Profile (AGP) metrics, such as Time in Range (TIR), Time Below Range (TBR), and Time Above Range (TAR).…

Machine Learning · Computer Science 2025-10-09 Canyu Lei , Benjamin Lobo , Jianxin Xie

One major impediment to the wider use of deep learning for clinical decision making is the difficulty of assigning a level of confidence to model predictions. Currently, deep Bayesian neural networks and sparse Gaussian processes are the…

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

Accurate long-horizon glucose forecasting is critical for automated insulin delivery systems, which help people with type 1 diabetes (T1D) manage their glucose and avoid dangerous hypoglycemia. However, standard recursive long short-term…

Machine Learning · Computer Science 2026-05-19 Phat Tran , Neville Mehta , Clara Mosquera-Lopez , Robert H. Dodier , Lizhong Chen , Peter G. Jacobs

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

In the world today, diabetic complications are a major factor in the disease's high mortality rate. Diabetes mellitus has been a major source of concern for decades due to its global prevalence and the resulting rising costs to individuals,…

Medical Physics · Physics 2023-10-18 Umme Hafsa Momy

In the case of diabetes, fingertip pricking for a blood sample is inconvenient for glucose measurement. Invasive approaches like laboratory test and one-touch glucometer enhance the risk of blood-related infections. To mitigate this…

Signal Processing · Electrical Eng. & Systems 2021-06-28 Prateek Jain , Amit M. Joshi , Saraju P. Mohanty

Diabetes prediction is an important data science application in the social healthcare domain. There exist two main challenges in the diabetes prediction task: data heterogeneity since demographic and metabolic data are of different types,…

This work presents a Model Predictive Control (MPC) for the artificial pancreas, which is able to autonomously manage basal insulin injections in type 1 diabetic patients. Specifically, the MPC goal is to maintain the patients' blood…

Systems and Control · Electrical Eng. & Systems 2024-01-31 Beatrice Sonzogni , José María Manzano , Marco Polver , Fabio Previdi , Antonio Ferramosca

Deep neural networks have become larger over the years with increasing demand of computational resources for inference; incurring exacerbate costs and leaving little room for deployment on devices with limited battery and other resources…

Machine Learning · Computer Science 2021-09-28 Aaqib Saeed