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We develop a new model of insulin-glucose dynamics for forecasting blood glucose in type 1 diabetics. We augment an existing biomedical model by introducing time-varying dynamics driven by a machine learning sequence model. Our model…
Background and objective: Diabetes is one of the four leading causes of death worldwide, necessitating daily blood glucose monitoring. While sweat offers a promising non-invasive alternative for glucose monitoring, its application remains…
The global diabetes epidemic highlights the importance of maintaining good glycemic control. Glucose prediction is a fundamental aspect of diabetes management, facilitating real-time decision-making. Recent research has introduced models…
Blood glucose value prediction is an important task in diabetes management. While it is reported that glucose concentration is sensitive to social context such as mood, physical activity, stress, diet, alongside the influence of diabetes…
Progress in the biomedical field through the use of deep learning is hindered by the lack of interpretability of the models. In this paper, we study the RETAIN architecture for the forecasting of future glucose values for diabetic people.…
Type 1 Diabetes (T1D) affects millions worldwide, requiring continuous monitoring to prevent severe hypo- and hyperglycemic events. While continuous glucose monitoring has improved blood glucose management, deploying predictive models on…
In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…
The problem of real time prediction of blood glucose (BG) levels based on the readings from a continuous glucose monitoring (CGM) device is a problem of great importance in diabetes care, and therefore, has attracted a lot of research in…
This paper presents the Derivatives Combination Predictor (DCP), a novel model fusion algorithm for making long-term glucose predictions for diabetic people. First, using the history of glucose predictions made by several models, the future…
Precise glucose level monitoring is critical for people with diabetes to avoid serious complications. While there are several methods for continuous glucose level monitoring, research on maintenance devices is limited. To mitigate the gap,…
Diabetes is a chronic metabolic disorder characterized by persistently high blood glucose levels (BGLs), leading to severe complications such as cardiovascular disease, neuropathy, and retinopathy. Predicting BGLs enables patients to…
Blood glucose simulation allows the effectiveness of type 1 diabetes (T1D) management strategies to be evaluated without patient harm. Deep learning algorithms provide a promising avenue for extending simulator capabilities; however, these…
In this paper we investigate the use of model-based reinforcement learning to assist people with Type 1 Diabetes with insulin dose decisions. The proposed architecture consists of multiple Echo State Networks to predict blood glucose levels…
The mathematical modelling of biological systems has historically followed one of two approaches: comprehensive and minimal. In comprehensive models, the involved biological pathways are modelled independently, then brought together as an…
With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses…
Blood glucose (BG) management is crucial for type-1 diabetes patients resulting in the necessity of reliable artificial pancreas or insulin infusion systems. In recent years, deep learning techniques have been utilized for a more accurate…
The rising rates of diabetes necessitate innovative methods for its management. Continuous glucose monitors (CGM) are small medical devices that measure blood glucose levels at regular intervals providing insights into daily patterns of…
In the context of time-series forecasting, we propose a LSTM-based recurrent neural network architecture and loss function that enhance the stability of the predictions. In particular, the loss function penalizes the model, not only on the…
Type 1 Diabetes is a chronic autoimmune condition in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, resulting in little to no insulin production. Insulin helps glucose in your blood enter your…
Blood glucose level monitoring is of great importance, especially for subjects experiencing type 1 diabetes. Accurate monitoring of their blood glucose level prevents dangerous and life-threatening situations that might be experienced by…