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Electronic health records include information on patients' status and medical history, which could cover the history of diseases and disorders that could be hereditary. One important use of family history information is in precision health,…

Computation and Language · Computer Science 2024-03-18 Xiang Dai , Sarvnaz Karimi , Nathan O'Callaghan

Mining electronic health records for patients who satisfy a set of predefined criteria is known in medical informatics as phenotyping. Phenotyping has numerous applications such as outcome prediction, clinical trial recruitment, and…

Computation and Language · Computer Science 2018-05-08 Dmitriy Dligach , Timothy Miller

Natural language processing (NLP) has been traditionally applied to medicine, and generative large language models (LLMs) have become prominent recently. However, the differences between them across different medical tasks remain…

Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…

Deep phenotyping is the detailed description of patient signs and symptoms using concepts from an ontology. The deep phenotyping of the numerous physician notes in electronic health records requires high throughput methods. Over the past…

Computation and Language · Computer Science 2024-03-12 Syed I. Munzir , Daniel B. Hier , Michael D. Carrithers

Despite advances in machine learning (ML) and large language models (LLMs), rule-based natural language processing (NLP) systems remain active in clinical settings due to their interpretability and operational efficiency. However, their…

Computation and Language · Computer Science 2025-06-23 Jianlin Shi , Brian T. Bucher

Computational phenotyping is essential for biomedical research but often requires significant time and resources, especially since traditional methods typically involve extensive manual data review. While machine learning and natural…

Computation and Language · Computer Science 2025-07-08 Sarah Pungitore , Shashank Yadav , Vignesh Subbian

The combined growth of available data and their unstructured nature has received increased interest in natural language processing (NLP) techniques to make value of these data assets since this format is not suitable for statistical…

Computation and Language · Computer Science 2023-04-07 Vitor Alcantara Batista , Alexandre Gonçalves Evsukoff

Electronic Health Records (EHR) are data generated during routine clinical care. EHR offer researchers unprecedented phenotypic breadth and depth and have the potential to accelerate the pace of precision medicine at scale. A main EHR…

Quantitative Methods · Quantitative Biology 2017-04-28 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Text-based representations of chemicals and proteins can be thought of as unstructured languages codified by humans to describe domain-specific knowledge. Advances in natural language processing (NLP) methodologies in the processing of…

Biomolecules · Quantitative Biology 2020-02-17 Hakime Öztürk , Arzucan Özgür , Philippe Schwaller , Teodoro Laino , Elif Ozkirimli

The meaningful use of electronic health records (EHR) continues to progress in the digital era with clinical decision support systems augmented by artificial intelligence. A priority in improving provider experience is to overcome…

Computation and Language · Computer Science 2023-01-30 Yanjun Gao , Dmitriy Dligach , Timothy Miller , John Caskey , Brihat Sharma , Matthew M Churpek , Majid Afshar

Understanding patterns of diagnoses, medications, procedures, and laboratory tests from electronic health records (EHRs) and health insurer claims is important for understanding disease risk and for efficient clinical development, which…

Machine Learning · Computer Science 2022-11-16 Ying Xu , Romane Gauriau , Anna Decker , Jacob Oppenheim

With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

Clinical notes are an essential component of a health record. This paper evaluates how natural language processing (NLP) can be used to identify the risk of acute care use (ACU) in oncology patients, once chemotherapy starts. Risk…

Computation and Language · Computer Science 2023-06-28 Claudio Fanconi , Marieke van Buchem , Tina Hernandez-Boussard

Natural Language Processing (NLP) has transformed various fields beyond linguistics by applying techniques originally developed for human language to the analysis of biological sequences. This review explores the application of NLP methods…

Computation and Language · Computer Science 2025-06-04 Ella Rannon , David Burstein

With a focus on natural language processing (NLP) and the role of large language models (LLMs), we explore the intersection of machine learning, deep learning, and artificial intelligence. As artificial intelligence continues to…

The digitalization of stored information in hospitals now allows for the exploitation of medical data in text format, as electronic health records (EHRs), initially gathered for other purposes than epidemiology. Manual search and analysis…

This technical report introduces a Named Clinical Entity Recognition Benchmark for evaluating language models in healthcare, addressing the crucial natural language processing (NLP) task of extracting structured information from clinical…

Clinical notes contain an extensive record of a patient's health status, such as smoking status or the presence of heart conditions. However, this detail is not replicated within the structured data of electronic health systems.…

Computation and Language · Computer Science 2020-09-18 Andriy Mulyar , Elliot Schumacher , Masoud Rouhizadeh , Mark Dredze

Deep learning methods employ multiple processing layers to learn hierarchical representations of data and have produced state-of-the-art results in many domains. Recently, a variety of model designs and methods have blossomed in the context…

Computation and Language · Computer Science 2018-11-27 Tom Young , Devamanyu Hazarika , Soujanya Poria , Erik Cambria