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Spectral embedding of network adjacency matrices often produces node representations living approximately around low-dimensional submanifold structures. In particular, hidden substructure is expected to arise when the graph is generated…

Machine Learning · Statistics 2022-06-27 Francesco Sanna Passino , Nicholas A. Heard

The proper design of DNA sequences allows for the formation of well defined supramolecular units with controlled interactions via a consecution of self-assembling processes. Here, we benefit from the controlled DNA self-assembly to…

Soft Condensed Matter · Physics 2018-02-14 Javier Fernandez-Castanon , Francesca Bomboi , Francesco Sciortino

Consider two independent random strings having same length and taking values uniformly in a common finite alphabet. We study the order of the variance of the length of the longest common subsequences (LCS) of these strings when long blocks,…

Probability · Mathematics 2016-09-26 S. Amsalu , C. Houdré , H. Matzinger

Popular network models such as the mixed membership and standard stochastic block model are known to exhibit distinct geometric structure when embedded into $\mathbb{R}^{d}$ using spectral methods. The resulting point cloud concentrates…

Statistics Theory · Mathematics 2021-10-15 Vinesh Solanki , Patrick Rubin-Delanchy , Ian Gallagher

We modify and extend the recently developed statistical mechanical model for predicting the thermodynamic properties of chain molecules having noncovalent double-stranded conformations, as in RNA or ssDNA, and $\beta-$sheets in protein, by…

Soft Condensed Matter · Physics 2009-11-07 Fei Liu , Luru Dai , Zhong-can Ou-Yang

RNA secondary structures of increasing complexity are probed combining single molecule stretching experiments and stochastic unfolding/refolding simulations. We find that force-induced unfolding pathways cannot usually be interpretated by…

Biological Physics · Physics 2015-06-26 S. Harlepp , T. Marchal , J. Robert , J-F. Leger , A. Xayaphoummine , H. Isambert , D. Chatenay

Statistical $\gamma$-decay from highly excited states is determined by the nuclear level density (NLD) and the $\gamma$-ray strength function ($\gamma$SF). These average quantities have been measured for several nuclei using the Oslo…

Geometric and structural constraints greatly restrict the selection of folds adapted by protein backbones, and yet, folded proteins show an astounding diversity in functionality. For structure to have any bearing on function, it is thus…

Biological Physics · Physics 2010-04-20 Brinda K. V. , Saraswathi Vishveshwara , Smitha Vishveshwara

Atomic nuclei are complex strongly interacting systems and their exact theoretical description is a long-standing challenge. An approximate description of nuclei can be achieved by separating its short and long range structure. This…

Nuclear Theory · Physics 2018-05-08 R. Weiss , R. Cruz-Torres , N. Barnea , E. Piasetzky , O. Hen

A growing number of RNA sequences are now known to have distributions of multiple stable sequences. Recent algorithms use the list of nucleotides in a sequence and auxiliary experimental data to predict such distributions. Although the…

Combinatorics · Mathematics 2020-09-14 Torin Greenwood , Christine E. Heitsch

We provide a novel family of generative block-models for random graphs that naturally incorporates degree distributions: the block-constrained configuration model. Block-constrained configuration models build on the generalised…

Physics and Society · Physics 2021-02-24 Giona Casiraghi

We consider finite linear or cyclic crystalline structures with molecular cells having narrow pre-threshold nuclear resonance. We prove that if the real part of such a nuclear resonance lies within the energy band (the convex hull of the…

Other Condensed Matter · Physics 2007-07-16 Alexander K. Motovilov , Vladimir B. Belyaev

We investigate theoretically the translocation of structured RNA/DNA molecules through narrow pores which allow single but not double strands to pass. The unzipping of basepaired regions within the molecules presents significant kinetic…

Soft Condensed Matter · Physics 2009-11-10 Ulrich Gerland , Ralf Bundschuh , Terence Hwa

We present a general setting for structure-sequence comparison in a large class of RNA structures that unifies and generalizes a number of recent works on specific families on structures. Our approach is based on tree decomposition of…

Quantitative Methods · Quantitative Biology 2012-06-21 Philippe Rinaudo , Yann Ponty , Dominique Barth , Alain Denise

We uncover the very rich graph topology of generic bounded non-Hermitian spectra, distinct from the topology of conventional band invariants and complex spectral winding. The graph configuration of complex spectra are characterized by the…

Mesoscale and Nanoscale Physics · Physics 2023-07-06 Tommy Tai , Ching Hua Lee

RNA viruses form genetically diverse populations structured as mutant spectra, or quasispecies, whose internal organization influences their evolutionary and adaptive dynamics. While genetic diversity has been extensively characterized, the…

It has been well accepted that the RNA secondary structures of most functional non-coding RNAs (ncRNAs) are closely related to their functions and are conserved during evolution. Hence, prediction of conserved secondary structures from…

Biomolecules · Quantitative Biology 2013-07-09 Michiaki Hamada

Let $G$ be a finite abelian group and $A$ a subset of $G$. The spectrum of $A$ is the set of its large Fourier coefficients. Known combinatorial results on the structure of spectrum, such as Chang's theorem, become trivial in the regime…

Combinatorics · Mathematics 2015-04-07 Kaave Hosseini , Shachar Lovett

We analyze the thermodynamic properties of a simplified model for folded RNA molecules recently studied by G. Vernizzi, H. Orland, A. Zee (in {\it Phys. Rev. Lett.} {\bf 94} (2005) 168103). The model consists of a chain of one-flavor base…

Biomolecules · Quantitative Biology 2009-11-13 Matias dell'Erba , Guillermo R. Zemba

We study the amount of reliable information that can be stored in a DNA-based storage system composed of short DNA molecules. In this regime, Shomorony and Heckel (2022) put forward a conjecture on the scaling of the number of information…

Information Theory · Computer Science 2025-11-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas