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Deep learning has achieved significant breakthroughs in medical imaging, but these advancements are often dependent on large, well-annotated datasets. However, obtaining such datasets poses a significant challenge, as it requires…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Siteng Ma , Honghui Du , Yu An , Jing Wang , Qinqin Wang , Haochang Wu , Aonghus Lawlor , Ruihai Dong

One fundamental statistical question for research areas such as precision medicine and health disparity is about discovering effect modification of treatment or exposure by observed covariates. We propose a semiparametric framework for…

Methodology · Statistics 2020-08-04 Muxuan Liang , Menggang Yu

A simple and common type of medical research involves the comparison of one treatment against another. The logical aim should be both to establish which treatment is superior and the strength of evidence supporting this conclusion, a task…

Methodology · Statistics 2022-12-08 Nicholas Adams

In this paper, we investigate the hypothesis testing problem that checks whether part of covariates / confounders significantly affect the heterogeneous treatment effect given all covariates. This model checking is particularly useful in…

Statistics Theory · Mathematics 2020-09-24 Niwen Zhou , Xu Guo , Lixing Zhu

The Shear TEsting Programme (STEP) is a collaborative project to improve the accuracy and reliability of weak lensing measurement, in preparation for the next generation of wide-field surveys. We review sixteen current and emerging shear…

As light travels through a disordered medium such as biological tissues, it undergoes multiple scattering events. This phenomenon is detrimental to in-depth optical microscopy, as it causes a drastic degradation of contrast, resolution and…

This paper considers the problem of testing whether there exists a solution satisfying certain non-negativity constraints to a linear system of equations. Importantly and in contrast to some prior work, we allow all parameters in the system…

This paper addresses patient heterogeneity associated with prediction problems in biomedical applications. We propose a systematic hypothesis testing approach to determine the existence of patient subgroup structure and the number of…

Methodology · Statistics 2021-01-08 Xu Gao , Weining Shen , Jing Ning , Ziding Feng , Jianhua Hu

We present a new approach to singularity confinement which makes it an efficient and reliable discrete integrability detector. Our method is based on the full-deautonomisation procedure, which consists in analysing non-autonomous extensions…

Mathematical Physics · Physics 2015-10-28 Basil Grammaticos , Alfred Ramani , Ralph Willox , Takafumi Mase , Junkichi Satsuma

Bayesian methods are useful for statistical inference. However, real-world problems can be challenging using Bayesian methods when the data analyst has only limited prior knowledge. In this paper we consider a class of problems, called…

Methodology · Statistics 2019-11-20 Yixuan Qiu , Lingsong Zhang , Chuanhai Liu

The problem of testing hypothesis that a density function has no more than $\mu$ derivatives versus it has more than $\mu$ derivatives is considered. For a solution, the $L^2$ norms of wavelet orthogonal projections on some orthogonal…

Statistics Theory · Mathematics 2018-09-11 Bogdan Ćmiel , Karol Dziedziul , Barbara Wolnik

Recent advances in probabilistic modelling have led to a large number of simulation-based inference algorithms which do not require numerical evaluation of likelihoods. However, a public benchmark with appropriate performance metrics for…

Machine Learning · Statistics 2021-04-12 Jan-Matthis Lueckmann , Jan Boelts , David S. Greenberg , Pedro J. Gonçalves , Jakob H. Macke

Diagnosing and mitigating changes in model fairness under distribution shift is an important component of the safe deployment of machine learning in healthcare settings. Importantly, the success of any mitigation strategy strongly depends…

How should researchers analyze randomized experiments in which the main outcome is latent and measured in multiple ways but each measure contains some degree of error? We first identify a critical study-specific noncomparability problem in…

Econometrics · Economics 2026-01-13 Jiawei Fu , Donald P. Green

The goal of mediation analysis is to study the effect of exposure on an outcome interceded by a mediator. Two simple hypotheses are tested: the effect of the exposure on the mediator, and the effect of the mediator on the outcome. When…

Statistics Theory · Mathematics 2021-06-01 Yotam Leibovici , Yair Goldberg

Blind Descent uses constrained but, guided approach to learn the weights. The probability density function is non-zero in the infinite space of the dimension (case in point: Gaussians and normal probability distribution functions). In Blind…

Machine Learning · Computer Science 2021-02-22 Prasad N R

Ptychography involves a sample being illuminated by a coherent, localised probe of illumination. When the probe interacts with the sample, the light is diffracted and a diffraction pattern is detected. Then the probe or sample is shifted…

Numerical Analysis · Mathematics 2023-05-09 Mark Philip Roach

Bayesian sparse factor models have proven useful for characterizing dependence in multivariate data, but scaling computation to large numbers of samples and dimensions is problematic. We propose expandable factor analysis for scalable…

Methodology · Statistics 2018-06-21 Sanvesh Srivastava , Barbara E. Engelhardt , David B. Dunson

Cognitive decline is a natural part of aging. However, under some circumstances, this decline is more pronounced than expected, typically due to disorders such as Alzheimer's disease. Early detection of an anomalous decline is crucial, as…

Threshold tests have recently been proposed as a useful method for detecting bias in lending, hiring, and policing decisions. For example, in the case of credit extensions, these tests aim to estimate the bar for granting loans to white and…

Machine Learning · Statistics 2018-03-13 Emma Pierson , Sam Corbett-Davies , Sharad Goel