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Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Shahira Abousamra , David Belinsky , John Van Arnam , Felicia Allard , Eric Yee , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Histopathologic diagnosis relies on simultaneous integration of information from a broad range of scales, ranging from nuclear aberrations ($\approx \mathcal{O}(0.1{\mu m})$) through cellular structures ($\approx \mathcal{O}(10{\mu m})$) to…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 Rüdiger Schmitz , Frederic Madesta , Maximilian Nielsen , Jenny Krause , René Werner , Thomas Rösch

Histology method is vital in the diagnosis and prognosis of cancers and many other diseases. For the analysis of histopathological images, we need to detect and segment all gland structures. These images are very challenging, and the task…

Image and Video Processing · Electrical Eng. & Systems 2019-11-05 Safiye Rezaei , Ali Emami , Nader Karimi , Shadrokh Samavi

Digital histology images are amenable to the application of convolutional neural network (CNN) for analysis due to the sheer size of pixel data present in them. CNNs are generally used for representation learning from small image patches…

Image and Video Processing · Electrical Eng. & Systems 2019-07-24 Muhammad Shaban , Ruqayya Awan , Muhammad Moazam Fraz , Ayesha Azam , David Snead , Nasir M. Rajpoot

Breast histology image classification is a crucial step in the early diagnosis of breast cancer. In breast pathological diagnosis, Convolutional Neural Networks (CNNs) have demonstrated great success using digitized histology slides.…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Zakaria Senousy , Mohammed M. Abdelsamea , Mohamed Medhat Gaber , Moloud Abdar , U Rajendra Acharya , Abbas Khosravi , Saeid Nahavandi

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

The segmentation of histopathological whole slide images into tumourous and non-tumourous types of tissue is a challenging task that requires the consideration of both local and global spatial contexts to classify tumourous regions…

The automated segmentation of cancer tissue in histopathology images can help clinicians to detect, diagnose, and analyze such disease. Different from other natural images used in many convolutional networks for benchmark, histopathology…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Juan P. Vigueras-Guillén , Joan Lasenby , Frank Seeliger

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

We propose HookNet, a semantic segmentation model for histopathology whole-slide images, which combines context and details via multiple branches of encoder-decoder convolutional neural networks. Concentricpatches at multiple resolutions…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Mart van Rijthoven , Maschenka Balkenhol , Karina Siliņa , Jeroen van der Laak , Francesco Ciompi

Convolutional Neural Networks can be designed with different levels of complexity depending upon the task at hand. This paper analyzes the effect of dimensional changes to the CNN architecture on its performance on the task of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Shreyas Rajesh Labhsetwar , Alistair Michael Baretto , Raj Sunil Salvi , Piyush Arvind Kolte , Veerasai Subramaniam Venkatesh

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Breast cancer is the most frequently diagnosed cancer and leading cause of cancer-related death among females worldwide. In this article, we investigate the applicability of densely connected convolutional neural networks to the problems of…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Matthias Kohl , Christoph Walz , Florian Ludwig , Stefan Braunewell , Maximilian Baust

Convolutional neural networks (CNNs) have been recently used for a variety of histology image analysis. However, availability of a large dataset is a major prerequisite for training a CNN which limits its use by the computational pathology…

Computer Vision and Pattern Recognition · Computer Science 2018-03-07 Ruqayya Awan , Navid Alemi Koohbanani , Muhammad Shaban , Anna Lisowska , Nasir Rajpoot

Pathologic analysis of surgical excision specimens for breast carcinoma is important to evaluate the completeness of surgical excision and has implications for future treatment. This analysis is performed manually by pathologists reviewing…

Image and Video Processing · Electrical Eng. & Systems 2021-01-22 David Joon Ho , Dig V. K. Yarlagadda , Timothy M. D'Alfonso , Matthew G. Hanna , Anne Grabenstetter , Peter Ntiamoah , Edi Brogi , Lee K. Tan , Thomas J. Fuchs

Histopathology images contain essential information for medical diagnosis and prognosis of cancerous disease. Segmentation of glands in histopathology images is a primary step for analysis and diagnosis of an unhealthy patient. Due to the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Safiyeh Rezaei , Ali Emami , Hamidreza Zarrabi , Shima Rafiei , Kayvan Najarian , Nader Karimi , Shadrokh Samavi , S. M. Reza Soroushmehr

Spatial arrangement of cells of various types, such as tumor infiltrating lymphocytes and the advancing edge of a tumor, are important features for detecting and characterizing cancers. However, convolutional neural networks (CNNs) do not…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Shrey Gadiya , Deepak Anand , Amit Sethi

Set classification problems arise when classification tasks are based on sets of observations as opposed to individual observations. In set classification, a classification rule is trained with $N$ sets of observations, where each set is…

Methodology · Statistics 2016-03-08 Sungkyu Jung , Xingye Qiao
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