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Diffusion-weighted magnetic resonance imaging (DW-MRI) is a non-invasive way of imaging white matter tracts in the human brain. DW-MRIs are usually acquired using echo-planar imaging (EPI) with high gradient fields, which could introduce…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Zhangxing Bian , Muhan Shao , Aaron Carass , Jerry L. Prince

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Magnetic Resonance Imaging (MRI) is a powerful medical imaging modality, but unfortunately suffers from long scan times which, aside from increasing operational costs, can lead to image artifacts due to patient motion. Motion during the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Brett Levac , Sidharth Kumar , Ajil Jalal , Jonathan I. Tamir

Computational models of biophysical tissue properties have been widely used in diffusion MRI (dMRI) research to elucidate the link between microstructural properties and MR signal formation. For brain tissue, the research community has…

Medical Physics · Physics 2019-07-16 Santiago Coelho , Jose M. Pozo , Sune N. Jespersen , Alejandro F. Frangi

Multimodal medical images play a crucial role in the precise and comprehensive clinical diagnosis. Diffusion model is a powerful strategy to synthesize the required medical images. However, existing approaches still suffer from the problem…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Jiahua Xu , Dawei Zhou , Lei Hu , Zaiyi Liu , Nannan Wang , Xinbo Gao

Multimodal medical image fusion integrates complementary information from different imaging modalities to enhance diagnostic accuracy and treatment planning. While deep learning methods have advanced performance, existing approaches face…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Meng Zhou , Farzad Khalvati

Magnetic Resonance (MR) image reconstruction from under-sampled acquisition promises faster scanning time. To this end, current State-of-The-Art (SoTA) approaches leverage deep neural networks and supervised training to learn a recovery…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Cheng Peng , Pengfei Guo , S. Kevin Zhou , Vishal Patel , Rama Chellappa

Brain cell structure and function reflect neurodevelopment, plasticity and ageing, and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to non-invasively…

Generative machine learning models have revolutionized material discovery by capturing complex structure-property relationships, yet extending these approaches to the inverse design of three-dimensional metamaterials remains limited by…

Computational Engineering, Finance, and Science · Computer Science 2026-04-27 Li Zheng , Siddhant Kumar , Dennis M. Kochmann

Dynamic Magnetic Resonance Imaging (MRI) is a crucial non-invasive method used to capture the movement of internal organs and tissues, making it a key tool for medical diagnosis. However, dynamic MRI faces a major challenge: long…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Tamir Shor , Chaim Baskin , Alex Bronstein

Quantitative description of the statistics of intensity fluctuations within spectral line data cubes introduced in our earlier work is extended to the absorbing media. A possibility of extracting 3D velocity and density statistics from both…

Astrophysics · Physics 2009-11-10 A. Lazarian , D. Pogosyan

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

Spine injections are commonly performed in several clinical procedures. The localization of the target vertebral level (i.e. the position of a vertebra in a spine) is typically done by back palpation or under X-ray guidance, yielding either…

Image and Video Processing · Electrical Eng. & Systems 2020-02-27 Maria Tirindelli , Maria Victorova , Javier Esteban , Seong Tae Kim , David Navarro-Alarcon , Yong Ping Zheng , Nassir Navab

Fluorescence microscopes can record the dynamics of living cells with high spatio-temporal resolution in a single plane. However, monitoring rapid and dim fluorescence fluctuations, e.g induced by neuronal activity in the brain, remains…

In this study we develop dimension-reduction techniques to accelerate diffusion model inference in the context of synthetic data generation. The idea is to integrate compressed sensing into diffusion models (hence, CSDM): First, compress…

Machine Learning · Statistics 2025-09-30 Zhengyi Guo , Jiatu Li , Wenpin Tang , David D. Yao

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Modelling the diffusion-relaxation magnetic resonance (MR) signal obtained from multi-parametric sequences has recently gained immense interest in the community due to new techniques significantly reducing data acquisition time. A preferred…

Medical Physics · Physics 2025-01-28 Fabian Bogusz , Tomasz Pieciak

Ultrasound is a widely accessible and cost-effective medical imaging tool commonly used for prenatal evaluation of the fetal brain. However, it has limitations, particularly in the third trimester, where the complexity of the fetal brain…

Image and Video Processing · Electrical Eng. & Systems 2025-04-04 Naomi Silverstein , Efrat Leibowitz , Ron Beloosesky , Haim Azhari

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

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