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Ischemic stroke lesion segmentation from Computed Tomography Perfusion (CTP) images is important for accurate diagnosis of stroke in acute care units. However, it is challenged by low image contrast and resolution of the perfusion parameter…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Guotai Wang , Tao Song , Qiang Dong , Mei Cui , Ning Huang , Shaoting Zhang

Perfusion imaging is the current gold standard for acute ischemic stroke analysis. It allows quantification of the salvageable and non-salvageable tissue regions (penumbra and core areas respectively). In clinical settings, the singular…

Image and Video Processing · Electrical Eng. & Systems 2021-04-01 Ezequiel de la Rosa , David Robben , Diana M. Sima , Jan S. Kirschke , Bjoern Menze

Deep learning based disease detection and segmentation algorithms promise to improve many clinical processes. However, such algorithms require vast amounts of annotated training data, which are typically not available in the medical context…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Moritz Platscher , Jonathan Zopes , Christian Federau

Early and accurate detection of Alzheimer's disease (AD) is crucial for enabling timely intervention and improving outcomes. However, developing reliable machine learning (ML) models for AD diagnosis is challenging due to limited labeled…

Machine Learning · Computer Science 2025-11-27 Abolfazl Moslemi , Hossein Peyvandi

One of the fundamental problems within the field of machine learning is dimensionality reduction. Dimensionality reduction methods make it possible to combat the so-called curse of dimensionality, visualize high-dimensional data and, in…

Machine Learning · Computer Science 2025-05-12 Sergio García-Heredia , Ángela Fernández , Carlos M. Alaíz

Perfusion imaging is crucial in acute ischemic stroke for quantifying the salvageable penumbra and irreversibly damaged core lesions. As such, it helps clinicians to decide on the optimal reperfusion treatment. In perfusion CT imaging,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Ezequiel de la Rosa , Diana M. Sima , Bjoern Menze , Jan S. Kirschke , David Robben

Consistency models have been proposed for fast generative modeling, achieving results competitive with diffusion and flow models. However, these methods exhibit inherent instability and limited reproducibility when training from scratch,…

Machine Learning · Computer Science 2026-02-02 Youngjoong Kim , Duhoe Kim , Woosung Kim , Jaesik Park

Despite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Johanna P. Müller , Anika Knupfer , Pedro Blöss , Edoardo Berardi Vittur , Bernhard Kainz , Jana Hutter

Score-based diffusion models provide a powerful way to model images using the gradient of the data distribution. Leveraging the learned score function as a prior, here we introduce a way to sample data from a conditional distribution given…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Hyungjin Chung , Jong Chul Ye

Purpose: To develop biophysics-based method for estimating perfusion Q from arterial spin labeling (ASL) images using deep learning. Methods: A 3D U-Net (QTMnet) was trained to estimate perfusion from 4D tracer propagation images. The…

Quantitative Methods · Quantitative Biology 2023-11-20 Renjiu Hu , Qihao Zhang , Pascal Spincemaille , Thanh D. Nguyen , Yi Wang

Background. Fully automatic analysis of myocardial perfusion MRI datasets enables rapid and objective reporting of stress/rest studies in patients with suspected ischemic heart disease. Developing deep learning techniques that can analyze…

We propose a simple, efficient, yet powerful framework for dense visual predictions based on the conditional diffusion pipeline. Our approach follows a "noise-to-map" generative paradigm for prediction by progressively removing noise from a…

Computer Vision and Pattern Recognition · Computer Science 2023-05-16 Yuanfeng Ji , Zhe Chen , Enze Xie , Lanqing Hong , Xihui Liu , Zhaoqiang Liu , Tong Lu , Zhenguo Li , Ping Luo

We propose a novel pipeline for the generation of synthetic ultrasound images via Denoising Diffusion Probabilistic Models (DDPMs) guided by cardiac semantic label maps. We show that these synthetic images can serve as a viable substitute…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 David Stojanovski , Uxio Hermida , Pablo Lamata , Arian Beqiri , Alberto Gomez

Deep-learning (DL)-based methods have shown significant promise in denoising myocardial perfusion SPECT images acquired at low dose. For clinical application of these methods, evaluation on clinical tasks is crucial. Typically, these…

Image and Video Processing · Electrical Eng. & Systems 2023-03-02 Md Ashequr Rahman , Zitong Yu , Barry A. Siegel , Abhinav K. Jha

In this paper we propose a convolutional neural network that is designed to upsample a series of sparse range measurements based on the contextual cues gleaned from a high resolution intensity image. Our approach draws inspiration from…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Shreyas S. Shivakumar , Ty Nguyen , Ian D. Miller , Steven W. Chen , Vijay Kumar , Camillo J. Taylor

Time is a fundamental factor during stroke treatments. A fast, automatic approach that segments the ischemic regions helps treatment decisions. In clinical use today, a set of color-coded parametric maps generated from computed tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Luca Tomasetti , Mahdieh Khanmohammadi , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz

A multitude of imaging and vision tasks have seen recently a major transformation by deep learning methods and in particular by the application of convolutional neural networks. These methods achieve impressive results, even for…

Computer Vision and Pattern Recognition · Computer Science 2018-11-30 Simon Arridge , Andreas Hauptmann

Speckle contrast imaging is an established technique to obtain relative blood maps over wide field of views. Currently, its most accurate implementation relies on the acquisition of raw speckle images at different exposure times but…

Medical Physics · Physics 2021-10-01 Marc Chammas , Frédéric Pain

Purpose: To develop a data-efficient strategy for accelerated MRI reconstruction with Diffusion Probabilistic Generative Models (DPMs) that enables faster scan times in clinical stroke MRI when only limited fully-sampled data samples are…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Yamin Arefeen , Sidharth Kumar , Steven Warach , Hamidreza Saber , Jonathan Tamir

The CT perfusion (CTP) is a medical exam for measuring the passage of a bolus of contrast solution through the brain on a pixel-by-pixel basis. The objective is to draw "perfusion maps" (namely cerebral blood volume, cerebral blood flow and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Daniele Perlo , Enzo Tartaglione , Umberto Gava , Federico D'Agata , Edwin Benninck , Mauro Bergui