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Deterministic approximations to stochastic Susceptible-Infectious-Susceptible models typically predict a stable endemic steady-state when above threshold. This can be hard to relate to the underlying stochastic dynamics, which has no…

Populations and Evolution · Quantitative Biology 2022-08-12 Christopher E. Overton , Robert R. Wilkinson , Adedapo Loyinmi , Joel C. Miller , Kieran J. Sharkey

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

Global strategies to contain a pandemic, such as social distancing and protective measures, are designed to reduce the overall transmission rate between individuals. Despite such measures, essential institutions, including hospitals,…

Populations and Evolution · Quantitative Biology 2022-09-07 Roberto Morán-Tovar , Henning Gruell , Florian Klein , Michael Lässig

Predicting the spread of vector-borne diseases in response to incursions requires knowledge of both host and vector demographics in advance of an outbreak. Whereas host population data is typically available, for novel disease introductions…

Populations and Evolution · Quantitative Biology 2015-06-02 Chris Jewell , Richard Brown

We propose a robust parameter estimation method for dynamical systems based on Statistical Learning techniques which aims to estimate a set of parameters that well fit the dynamics in order to obtain robust evidences about the qualitative…

Methodology · Statistics 2021-02-26 Diego Marcondes

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

We develop a stochastic two-patch epidemic model with nonlinear recidivism to investigate infectious disease dynamics in heterogeneous populations. Extending a deterministic framework, we introduce stochasticity to account for random…

Populations and Evolution · Quantitative Biology 2024-05-21 Juan G. Calvo , Mario I. Simoy , Juan P. Aparicio , José E. Chacón , Fabio Sanchez

The interplay of seasonality, the system's nonlinearities and intrinsic stochasticity is studied for a seasonally forced susceptible-exposed-infective-recovered stochastic model. The model is explored in the parameter region that…

Biological Physics · Physics 2010-10-19 Ganna Rozhnova , Ana Nunes

An individual-based model of the infectious disease spread among the urban population is considered. A system of stochastic equations, which describes changes in quantities of four population groups, susceptible, exposed, infected…

Populations and Evolution · Quantitative Biology 2011-11-11 Vasiliy Leonenko

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

Stochastic epidemic models describe the dynamics of an epidemic as a disease spreads through a population. Typically, only a fraction of cases are observed at a set of discrete times. The absence of complete information about the time…

Computation · Statistics 2017-02-14 Jonathan Fintzi , Xiang Cui , Jon Wakefield , Vladimir N. Minin

Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…

Methodology · Statistics 2024-12-18 Prayag Chatha , Fan Bu , Jeffrey Regier , Evan Snitkin , Jon Zelner

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

Populations and Evolution · Quantitative Biology 2026-05-13 Seong Jun Park

At the onset of the Covid-19 pandemic, a number of non-pharmaceutical interventions have been implemented in order to reduce transmission, thus leading to multiple phases of transmission. The disease reproduction number $R_t$, a way of…

Applications · Statistics 2023-05-03 Petros Barmpounakis , Nikolaos Demiris

Viruses constantly undergo mutations with genomic changes. The propagation of variants of viruses is an interesting problem. We perform numerical simulations of the microscopic epidemic model based on network theory for the spread of…

Populations and Evolution · Quantitative Biology 2025-01-14 Yutaka Okabe , Akira Shudo

We propose and analyze an epidemiological model for vector borne diseases that integrates a multi-stage vector population and several host sub-populations which may be characterized by a variety of compartmental model types: subpopulations…

Populations and Evolution · Quantitative Biology 2023-06-28 Francis G. T. Kamba , Leonard C. Eze , Jean Claude Kamgang , Christopher P. Thron

Effective utilization of flexible loads for grid services, while satisfying end-user preferences and constraints, requires an accurate estimation of the aggregated predictive flexibility offered by the electrical loads. Virtual battery (VB)…

Systems and Control · Electrical Eng. & Systems 2020-03-20 Indrasis Chakraborty , Sai Pushpak Nandanoori , Soumya Kundu , Karanjit Kalsi

We propose a deterministic SAIVRD model and a stochastic SARV model of the epidemic COVID-19 involving asymptomatic infections and vaccinations to conduct data forecasts using time-dependent parameters. The forecast by our deterministic…

Populations and Evolution · Quantitative Biology 2022-09-28 Bo-Sheng Chen , Zong-Ying Wu , Yen-Jia Chen , Jann-Long Chern

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

Human migration exhibits complex spatiotemporal dependence driven by environmental and socioeconomic forces. Modeling such patterns at scale requires methods that accommodate many random effects while remaining feasible when raw data or…

Methodology · Statistics 2026-05-29 Lida Chalangar Jalili Dehkharghani , Li-Hsiang Lin