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Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…

Computational Engineering, Finance, and Science · Computer Science 2016-09-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Brain connectomics is a developing field in neurosciences which strives to understand cognitive processes and psychiatric diseases through the analysis of interactions between brain regions. However, in the high-dimensional, low-sample, and…

Applications · Statistics 2019-11-15 Claire Donnat , Leonardo Tozzi , Susan Holmes

The brain's connectome and the vascular system are examples of physical networks whose tangible nature influences their structure, layout, and ultimately their function. The material resources required to build and maintain these networks…

Biological Physics · Physics 2025-09-30 Xiangyi Meng , Benjamin Piazza , Csaba Both , Baruch Barzel , Albert-László Barabási

A fundamental idea in neuroscience is that cognitive functions -- such as perception, learning, memory, and locomotion -- are shaped and constrained by the brain's structural organization. Despite significant progress in mapping and…

Neurons and Cognition · Quantitative Biology 2025-08-07 Elkaïoum M. Moutuou , Habib Benali

The assessment of brain fingerprints has emerged in the recent years as an important tool to study individual differences and to infer quality of neuroimaging datasets. Studies so far have mainly focused on connectivity fingerprints between…

Neurons and Cognition · Quantitative Biology 2021-01-13 Uttara Tipnis , Kausar Abbas , Elizabeth Tran , Enrico Amico , Li Shen , Alan D. Kaplan , Joaquín Goñi

In our previous study we have shown that the female connectomes have significantly better, deep graph-theoretical parameters, related to superior "connectivity", than the connectome of the males. Since the average female brain is smaller…

Neurons and Cognition · Quantitative Biology 2015-12-04 Balázs Szalkai , Bálint Varga , Vince Grolmusz

Recurrent networks are a special class of artificial neural systems that use their internal states to perform computing tasks for machine learning. One of its state-of-the-art developments, i.e. reservoir computing (RC), uses the internal…

Disordered Systems and Neural Networks · Physics 2022-11-02 Valeria d'Andrea , Michele Puppin , Manlio De Domenico

The brain's intricate connectome, a blueprint for its function, presents immense complexity, yet it arises from a compact genetic code, hinting at underlying low-dimensional organizational principles. This work bridges connectomics and…

Artificial Intelligence · Computer Science 2025-05-28 Yubin Li , Xingyu Liu , Guozhang Chen

This paper considers the use of machine learning algorithms for predicting cocaine use based on magnetic resonance imaging (MRI) connectomic data. The study utilized functional MRI (fMRI) and diffusion MRI (dMRI) data collected from 275…

We introduce TempoCave, a novel visualization application for analyzing dynamic brain networks, or connectomes. TempoCave provides a range of functionality to explore metrics related to the activity patterns and modular affiliations of…

Human-Computer Interaction · Computer Science 2020-01-16 Ran Xu , Manu Mathew Thomas , Alex Leow , Olusola Ajilore , Angus G. Forbes

Modern neuroimaging technologies, combined with state-of-the-art data processing pipelines, have made it possible to collect longitudinal observations of an individual's brain connectome at different ages. It is of substantial scientific…

Applications · Statistics 2019-08-16 Lu Wang , Zhengwu Zhang

Current theories hold that brain function is highly related to long-range physical connections through axonal bundles, namely extrinsic connectiv-ity. However, obtaining a groupwise cortical parcellation based on extrinsic connectivity…

Applications · Statistics 2017-01-06 Guillermo Gallardo , William Wells , Rachid Deriche , Demian Wassermann

One important question in neuroscience is how global behavior in a brain network emerges from the interplay between network connectivity and the neural dynamics of individual nodes. To better understand this theoretical relationship, we…

Neurons and Cognition · Quantitative Biology 2022-09-13 Anca Radulescu , Johan Nakuci , Simone Evans , Sarah Muldoon

Contemporary neuroimaging methods can shed light on the basis of human neural and cognitive specializations, with important implications for neuroscience and medicine. Different MRI acquisitions provide different brain networks at the…

Neurons and Cognition · Quantitative Biology 2016-02-23 C. Alonso-Montes , I. Diez , L. Remaki , I. Escudero , B. Mateos , Y. Rosseel , D. Marinazzo , S. Stramaglia , J. Cortes

The structural network of the brain, or structural connectome, can be represented by fiber bundles generated by a variety of tractography methods. While such methods give qualitative insights into brain structure, there is controversy over…

Computer Vision and Pattern Recognition · Computer Science 2022-06-15 Kristen M. Campbell , Haocheng Dai , Zhe Su , Martin Bauer , P. Thomas Fletcher , Sarang C. Joshi

The anatomical structure of the brain can be observed via non-invasive techniques such as diffusion imaging. However, these are imperfect because they miss connections that are actually known to exist, especially long range…

Neurons and Cognition · Quantitative Biology 2015-02-25 Somwrita Sarkar , Sanjay Chawla , Donna Xu

The shape of the brain's white matter connections is relatively unexplored in diffusion MRI tractography analysis. While it is known that tract shape varies in populations and across the human lifespan, it is unknown if the variability in…

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

Neurons and Cognition · Quantitative Biology 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

Functional connectivity varies across individuals due to genetic and environmental factors, yet classical twin models typically confound non-shared environment with measurement error and are largely limited to resting-state analyses. We…

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi