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Genetic information is encoded in a linear sequence of nucleotides, represented by letters ranging from thousands to billions. Mutations refer to changes in the DNA or RNA nucleotide sequence. Thus, mutation detection is vital in all areas…

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

We present an efficient phylogenetic reconstruction algorithm allowing insertions and deletions which provably achieves a sequence-length requirement (or sample complexity) growing polynomially in the number of taxa. Our algorithm is…

Probability · Mathematics 2013-02-25 Constantinos Daskalakis , Sebastien Roch

We have attempted in this paper to reduce the number of checked condition through saving frequency of the tandem replicated words, and also using non-overlapping iterative neighbor intervals on plane sweep algorithm. The essential idea of…

Data Structures and Algorithms · Computer Science 2012-11-20 Elahe Moghimi Hanjani , Mahdi Javanmard

A classical measure of string comparison is given by the longest common subsequence (LCS) problem on a pair of strings. We consider its generalisation, called the semi-local LCS problem, which arises naturally in many string-related…

Data Structures and Algorithms · Computer Science 2015-03-13 Alexander Tiskin

Traditional pairwise sequence alignment is based on matching individual samples from two sequences, under time monotonicity constraints. However, in many application settings matching subsequences (segments) instead of individual samples…

Databases · Computer Science 2016-09-28 Shahriar Shariat , Vladimir Pavlovic

In this paper we describe an algorithm for aligning sentences with their translations in a bilingual corpus using lexical information of the languages. Existing efficient algorithms ignore word identities and consider only the sentence…

Computation and Language · Computer Science 2007-05-23 Akshar Bharati , V. Sriram , A. Vamshi Krishna , Rajeev Sangal , S. M. Bendre

This article considers algorithmic and statistical aspects of linear regression when the correspondence between the covariates and the responses is unknown. First, a fully polynomial-time approximation scheme is given for the natural least…

Machine Learning · Computer Science 2017-11-09 Daniel Hsu , Kevin Shi , Xiaorui Sun

Given a set of incomplete observations, we study the nonparametric problem of testing whether data are Missing Completely At Random (MCAR). Our first contribution is to characterise precisely the set of alternatives that can be…

Statistics Theory · Mathematics 2022-05-19 Thomas B Berrett , Richard J Samworth

Tools that effectively analyze and compare sequences are of great importance in various areas of applied computational research, especially in the framework of molecular biology. In the present paper, we introduce simple geometric criteria…

Quantitative Methods · Quantitative Biology 2013-08-14 Boris Brimkov , Valentin E. Brimkov

Various methods have been developed to analyze the association between organisms and their genomic sequences. Among them, sequence alignment is the most frequently used for comparative analysis of biological genomes. However, the…

Quantitative Methods · Quantitative Biology 2020-10-27 Yong Joon Song , Dong Jin Ji , Hye In Seo , Gyu Bum Han , Dong Ho Cho

Protein similarity searches are a routine job for molecular biologists where a query sequence of amino acids needs to be compared and ranked against an ever-growing database of proteins. All available algorithms in this field can be grouped…

Computational Engineering, Finance, and Science · Computer Science 2015-08-27 Akash Nag , Sunil Karforma

We consider learning a sequence classifier without labeled data by using sequential output statistics. The problem is highly valuable since obtaining labels in training data is often costly, while the sequential output statistics (e.g.,…

Machine Learning · Computer Science 2017-05-30 Yu Liu , Jianshu Chen , Li Deng

In many applications, it is necessary to determine the string similarity. Edit distance[WF74] approach is a classic method to determine Field Similarity. A well known dynamic programming algorithm [GUS97] is used to calculate edit distance…

Data Structures and Algorithms · Computer Science 2007-05-23 Qi Xiao Yang , Sung Sam Yuan , Lu Chun , Li Zhao , Sun Peng

Parallel sentence extraction is a task addressing the data sparsity problem found in multilingual natural language processing applications. We propose an end-to-end deep neural network approach to detect translational equivalence between…

Computation and Language · Computer Science 2017-09-29 Francis Grégoire , Philippe Langlais

This study is to review the approaches used for measuring sentences similarity. Measuring similarity between natural language sentences is a crucial task for many Natural Language Processing applications such as text classification,…

Computation and Language · Computer Science 2019-10-10 Mamdouh Farouk

The equidistant subsequence pattern matching problem is considered. Given a pattern string $P$ and a text string $T$, we say that $P$ is an \emph{equidistant subsequence} of $T$ if $P$ is a subsequence of the text such that consecutive…

Data Structures and Algorithms · Computer Science 2020-02-18 Mitsuru Funakoshi , Yuto Nakashima , Shunsuke Inenaga , Hideo Bannai , Masayuki Takeda , Ayumi Shinohara

Wake word detection exists in most intelligent homes and portable devices. It offers these devices the ability to "wake up" when summoned at a low cost of power and computing. This paper focuses on understanding alignment's role in…

Computation and Language · Computer Science 2023-06-08 Vinicius Ribeiro , Yiteng Huang , Yuan Shangguan , Zhaojun Yang , Li Wan , Ming Sun

Most words have several senses and connotations which evolve in time due to semantic shift, so that closely related words may gain different or even opposite meanings over the years. This evolution is very relevant to the study of language…

Computation and Language · Computer Science 2018-05-31 Jean-François Delpech

Sequence discriminative training is a great tool to improve the performance of an automatic speech recognition system. It does, however, necessitate a sum over all possible word sequences, which is intractable to compute in practice.…

Computation and Language · Computer Science 2022-04-22 Nils-Philipp Wynands , Wilfried Michel , Jan Rosendahl , Ralf Schlüter , Hermann Ney
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