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The histogram method is a powerful non-parametric approach for estimating the probability density function of a continuous variable. But the construction of a histogram, compared to the parametric approaches, demands a large number of…

Machine Learning · Statistics 2015-12-29 Hideaki Kim , Hiroshi Sawada

Compositional data, representing proportions constrained to the simplex, arise in diverse fields such as geosciences, ecology, genomics, and microbiome research. Existing nonparametric density estimation methods often rely on…

Methodology · Statistics 2025-10-10 Jiajin Xie , Yong Wang , Eduardo García-Portugués

Current deep-learning-based registration algorithms often exploit intensity-based similarity measures as the loss function, where dense correspondence between a pair of moving and fixed images is optimized through backpropagation during…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 Xinzhe Luo , Xiahai Zhuang

Dirichlet process mixtures are flexible non-parametric models, particularly suited to density estimation and probabilistic clustering. In this work we study the posterior distribution induced by Dirichlet process mixtures as the sample size…

Statistics Theory · Mathematics 2022-11-29 Filippo Ascolani , Antonio Lijoi , Giovanni Rebaudo , Giacomo Zanella

Finite mixture models, typically Gaussian mixtures, are well known and widely used as model-based clustering. In practical situations, there are many non-Gaussian data that are heavy-tailed and/or asymmetric. Normal inverse Gaussian (NIG)…

Machine Learning · Statistics 2020-09-15 Takashi Takekawa

Wide-field imaging Mueller polarimetry is a revolutionary, label-free, and non-invasive modality for computer-aided intervention: in neurosurgery it aims to provide visual feedback of white matter fibre bundle orientation from derived…

Normalising flows are generative models that transform a complex density into a simpler density through the use of bijective transformations enabling both density estimation and data generation from a single model. %However, the requirement…

Machine Learning · Statistics 2024-06-28 Eshant English , Matthias Kirchler , Christoph Lippert

Within Bayesian nonparametrics, dependent Dirichlet process mixture models provide a highly flexible approach for conducting inference about the conditional density function. However, several formulations of this class make either rather…

Methodology · Statistics 2024-05-14 María Xosé Rodríguez-Álvarez , Vanda Inácio , Nadja Klein

By chaining a sequence of differentiable invertible transformations, normalizing flows (NF) provide an expressive method of posterior approximation, exact density evaluation, and sampling. The trend in normalizing flow literature has been…

Machine Learning · Computer Science 2020-10-20 Robert Giaquinto , Arindam Banerjee

In many scientific applications, the target probability distribution cannot be evaluated in closed form or sampled from directly. Instead, it can often be decomposed into multiple components, some of which are accessible only through…

Methodology · Statistics 2026-03-10 Roxana Darvishi , David C. Stenning , Ted von Hippel , Owen G. Ward

CLARITY is a method for converting biological tissues into translucent and porous hydrogel-tissue hybrids. This facilitates interrogation with light sheet microscopy and penetration of molecular probes while avoiding physical slicing. In…

Computer Vision and Pattern Recognition · Computer Science 2017-08-14 Kwame S. Kutten , Nicolas Charon , Michael I. Miller , J. T. Ratnanather , Jordan Matelsky , Alexander D. Baden , Kunal Lillaney , Karl Deisseroth , Li Ye , Joshua T. Vogelstein

Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Samuel St-Jean , Max A. Viergever , Alexander Leemans

Probabilistic finite mixture models are widely used for unsupervised clustering. These models can often be improved by adapting them to the topology of the data. For instance, in order to classify spatially adjacent data points similarly,…

Computer Vision and Pattern Recognition · Computer Science 2022-02-09 Jonathan Vacher , Claire Launay , Ruben Coen-Cagli

Deep learning models have emerged as a powerful tool for various medical applications. However, their success depends on large, high-quality datasets that are challenging to obtain due to privacy concerns and costly annotation. Generative…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Milad Yazdani , Yasamin Medghalchi , Pooria Ashrafian , Ilker Hacihaliloglu , Dena Shahriari

Image segmentation is a fundamental step for the interpretation of Remote Sensing Images. Clustering or segmentation methods usually precede the classification task and are used as support tools for manual labeling. The most common…

Computer Vision and Pattern Recognition · Computer Science 2022-03-08 Kiran Mantripragada , Faisal Z. Qureshi

The aim of this paper is to establish a nonlinear variational approach to the reconstruction of moving density images from indirect dynamic measurements. Our approach is to model the dynamics as a hyperelastic deformation of an initial…

Numerical Analysis · Mathematics 2015-12-01 Martin Burger , Jan Modersitzki , Sebastian Suhr

Density deconvolution is the task of estimating a probability density function given only noise-corrupted samples. We can fit a Gaussian mixture model to the underlying density by maximum likelihood if the noise is normally distributed, but…

Machine Learning · Statistics 2020-07-14 Tim Dockhorn , James A. Ritchie , Yaoliang Yu , Iain Murray

We introduce and demonstrate a new paradigm for quantitative parameter mapping in MRI. Parameter mapping techniques, such as diffusion MRI and quantitative MRI, have the potential to robustly and repeatably measure biologically-relevant…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Moucheng Xu , Yukun Zhou , Tobias Goodwin-Allcock , Kimia Firoozabadi , Joseph Jacob , Daniel C. Alexander , Paddy J. Slator

A normalizing flow models a complex probability density as an invertible transformation of a simple base density. Flows based on either coupling or autoregressive transforms both offer exact density evaluation and sampling, but rely on the…

Machine Learning · Statistics 2019-12-03 Conor Durkan , Artur Bekasov , Iain Murray , George Papamakarios

Model-driven analysis of biophysical phenomena is gaining increased attention and utility for medical imaging applications. In magnetic resonance imaging (MRI), the availability of well-established models for describing the relations…

Medical Physics · Physics 2023-10-31 Dinor Nagar , Nikita Vladimirov , Christian T. Farrar , Or Perlman