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Estimating a causal effect from observational data can be biased if we do not control for self-selection. This selection is based on confounding variables that affect the treatment assignment and the outcome. Propensity score methods aim to…

Econometrics · Economics 2021-09-10 Daniel Jacob

This paper reports our preliminary work on medical incident prediction in general, and fall risk prediction in specific, using machine learning. Data for the machine learning are generated only from the particular subset of the electronic…

Machine Learning · Computer Science 2021-09-16 Atsushi Yanagisawa , Chintaka Premachandra , Hiruharu Kawanaka , Atsushi Inoue , Takeo Hata , Eiichiro Ueda

Compartmental epidemic models with dynamics that evolve over a graph network have gained considerable importance in recent years but analysis of these models is in general difficult due to their complexity. In this paper, we develop two…

Populations and Evolution · Quantitative Biology 2023-05-31 Sei Zhen Khong , Lanlan Su

Accurate mortality modeling is central to actuarial science and public health, especially as mental health emerges as a significant factor in population outcomes. This paper develops and applies a Bayesian hierarchical model to analyze U.S.…

We propose a Multi-vAlue Rule Set (MRS) model for in-hospital predicting patient mortality. Compared to rule sets built from single-valued rules, MRS adopts a more generalized form of association rules that allows multiple values in a…

Artificial Intelligence · Computer Science 2018-07-24 Tong Wang , Veerajalandhar Allareddy , Sankeerth Rampa , Veerasathpurush Allareddy

Electronic health records (EHR) are characterized as non-stationary, heterogeneous, noisy, and sparse data; therefore, it is challenging to learn the regularities or patterns inherent within them. In particular, sparseness caused mostly by…

Machine Learning · Computer Science 2020-03-03 Eunji Jun , Ahmad Wisnu Mulyadi , Jaehun Choi , Heung-Il Suk

Although HRV (Heart Rate Variability) analyses have been carried out for several decades, several limiting factors still make these analyses useless from a clinical point of view. The present paper aims at overcoming some of these limits by…

Medical Physics · Physics 2013-11-07 Orazio A. Barra , Luciano Moretti

The United Nations' Sustainable Development Goal 3.2 aims to reduce under-5 child mortality to 25 deaths per 1,000 live births by 2030. Child mortality tends to be concentrated in developing regions where much of the information needed to…

Applications · Statistics 2018-10-10 Katie Wilson , Jon Wakefield

We propose a new approach for estimating causal effects when the exposure is measured with error and confounding adjustment is performed via a generalized propensity score (GPS). Using validation data, we propose a regression calibration…

Estimating the prevalence of a medical condition, or the proportion of the population in which it occurs, is a fundamental problem in healthcare and public health. Accurate estimates of the relative prevalence across groups -- capturing,…

Computers and Society · Computer Science 2023-12-13 Divya Shanmugam , Kaihua Hou , Emma Pierson

Difference-in-differences is based on a parallel trends assumption, which states that changes over time in average potential outcomes are independent of treatment assignment, possibly conditional on covariates. With time-varying treatments,…

Methodology · Statistics 2024-06-25 Nicholas Illenberger , Iván Díaz , Audrey Renson

Markov state models (MSMs) are widely employed to analyze the kinetics of complex systems. But despite their effectiveness in many applications, MSMs are prone to systematic or statistical errors, often exacerbated by suboptimal…

Data Analysis, Statistics and Probability · Physics 2025-08-12 Yehor Tuchkov , Luke Evans , Sonya M. Hanson , Erik H. Thiede

The Invariant Risk Minimization (IRM) principle was first proposed by Arjovsky et al. [2019] to address the domain generalization problem by leveraging data heterogeneity from differing experimental conditions. Specifically, IRM seeks to…

Machine Learning · Computer Science 2021-06-21 Kia Khezeli , Arno Blaas , Frank Soboczenski , Nicholas Chia , John Kalantari

Vital signs and laboratory values are routinely used to guide clinical decision-making for polytrauma patients, such as the decision to use damage control techniques versus early definitive fracture fixation. Prior multivariate models have…

Quantitative Methods · Quantitative Biology 2020-10-09 Adam J. Starr , Manjula Julka , Arun Nethi , John D. Watkins , Ryan W. Fairchild , Michael W. Cripps , Dustin Rinehart , Hayden N. Box

The decrease in the increase in death rates at old ages is a phenomenon that has repeatedly been discussed in demographic research. While mortality deceleration can be explained in the gamma-Gompertz model as an effect of selection in…

Applications · Statistics 2019-05-16 Marie Böhnstedt , Hein Putter , Nadine Ouellette , Gerda Claeskens , Jutta Gampe

Evidence from observational studies has become increasingly important for supporting healthcare policy making via cost-effectiveness (CE) analyses. Similar as in comparative effectiveness studies, health economic evaluations that consider…

This report presents a statistical analysis of the impact of key maternal characteristics, including age, smoking status, parity, height, weight, and gestation period, on newborn birth weight. A realworld dataset comprising 1,236…

Applications · Statistics 2025-09-03 Prithwiraj Chatterjee , Abhinav Tanwar , Devadharshini Udayakumar

This manuscript proposes a significant step in our long-run investigation of infant mortality across species. Since 2016 (Berrut et al. 2016) a succession of studies (Bois et al. 2019) have traced infant mortality from organisms of high…

Cell Behavior · Quantitative Biology 2021-03-26 Eduardo M. Garcia-Roger , Peter Richmond , Bertrand M. Roehner

Precision medicine leverages patient heterogeneity to estimate individualized treatment regimens, formalized, data-driven approaches designed to match patients with optimal treatments. In the presence of competing events, where multiple…

Correlation matrices are widely used to analyze the interdependence of variables in various real-world scenarios. Often, a perturbation in a few variables leads to mild differences in many correlation coefficients associated with these…

Applications · Statistics 2023-03-07 Itamar Faran , Michael Peer , Shahar Arzy , Yuval Benjamini
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