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Second-harmonic generation (SHG) microscopy provides label-free imaging of biological tissues with unique contrast mechanisms, but its resolution is limited by the diffraction limit. Here, we present the first experimental demonstration of…

Optics · Physics 2023-04-28 Jungho Moon , Sungsam Kang , Jin Hee Hong , Seokchan Yoon , Wonshik Choi

We report experimental results of parallel measurement of spectral components of the light. The temporal fluctuations of an optical field mixed with a separate reference are recorded with a high throughput complementary metal oxide…

Optics · Physics 2008-11-26 Michael Atlan , Michel Gross

Fourier ptychography is a recently developed imaging approach for large field-of-view and high-resolution microscopy. Here we model the Fourier ptychographic forward imaging process using a convolution neural network (CNN) and recover the…

Computer Vision and Pattern Recognition · Computer Science 2018-03-12 Shaowei Jiang , Kaikai Guo , Jun Liao , Guoan Zheng

This article experimentally examines different configurations of a novel multi-camera array microscope (MCAM) imaging technology. The MCAM is based upon a densely packed array of "micro-cameras" to jointly image across a large field-of-view…

There has been much progress in data-driven artificial intelligence technology for medical image analysis in the last decades. However, it still remains challenging due to its distinctive complexity of acquiring and annotating image data,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Chao Gou , Tianyu Shen , Wenbo Zheng , Huadan Xue , Hui Yu , Qiang Ji , Zhengyu Jin , Fei-Yue Wang

While Fourier ptychography (FP) offers super-resolution for macroscopic imaging, its real-world application is severely hampered by atmospheric turbulence, a challenge largely unaddressed in existing macroscopic FP research operating under…

In this paper, we propose a novel method for image fusion with a high-resolution panchromatic image and a low-resolution multispectral image at the same geographical location. The fusion is formulated as a convex optimization problem which…

Computer Vision and Pattern Recognition · Computer Science 2015-10-28 Chen Chen , Yeqing Li , Wei Liu , Junzhou Huang

Ptychography is an emerging imaging technique that is able to provide wavelength-limited spatial resolution from specimen with extended lateral dimensions. As a scanning microscopy method, a typical two-dimensional image requires a number…

Fourier ptychographic microscopy (FPM) is a promising computational imaging technique with high resolution, wide field-of-view (FOV) and quantitative phase recovery. So far, a series of system errors that may corrupt the image quality of…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 An Pan , Aiye Wang , Junfu Zheng , Yuting Gao , Caiwen Ma , Baoli Yao

Sparse Aperture Masking (SAM) allows for high-contrast imaging at small inner working angles, however the performance is limited by the small throughput and the number of baselines. We present the concept and first lab results of…

Instrumentation and Methods for Astrophysics · Physics 2018-08-03 David S. Doelman , Peter Tuthill , Barnaby Norris , Michael J. Wilby , Emiel H. Por , Christoph U. Keller , Michael J. Escuti , Frans Snik

Aims : We describe MS-MFS, a multi-scale multi-frequency deconvolution algorithm for wide-band synthesis-imaging, and present imaging results that illustrate the capabilities of the algorithm and the conditions under which it is feasible…

Instrumentation and Methods for Astrophysics · Physics 2015-05-28 Urvashi Rau , Tim J. Cornwell

This paper presents an application of digital Fourier holography for selective imaging of scatterers with different sizes in turbid media such as biological tissues. A combination of Fourier holography and high-resolution digital recording,…

Optics · Physics 2007-05-23 Sergey A. Alexandrov , P. Meredith , T. J. McIntyre , A. V. Zvyagin

Diagnostics capable of interrogating dynamics in harsh environments such as plasma have remained essentially unchanged in recent decades. Developments in advanced microscopy techniques will improve our understanding of the physics involved…

Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…

Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Medical Physics · Physics 2023-12-15 Irem Loc , Mehmet Burcin Unlu

High-throughput computational imaging requires efficient processing algorithms to retrieve multi-dimensional and multi-scale information. In computational phase imaging, phase retrieval (PR) is required to reconstruct both amplitude and…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Xuyang Chang , Liheng Bian , Jun Zhang

Convolutional neural networks are paramount in image and signal processing including the relevant classification and training tasks alike and constitute for the majority of machine learning compute demand today. With convolution operations…

Ptychography involves a sample being illuminated by a coherent, localised probe of illumination. When the probe interacts with the sample, the light is diffracted and a diffraction pattern is detected. Then the probe or sample is shifted…

Numerical Analysis · Mathematics 2023-05-09 Mark Philip Roach

In this work, we propose using camera arrays coupled with coherent illumination as an effective method of improving spatial resolution in long distance images by a factor of ten and beyond. Recent advances in ptychography have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2015-11-29 Jason Holloway , M. Salman Asif , Manoj Kumar Sharma , Nathan Matsuda , Roarke Horstmeyer , Oliver Cossairt , Ashok Veeraraghavan

Background: Tumour budding is an independent predictor of metastasis and prognosis in colorectal cancer and is a vital part of the pathology specification report. In a conventional pathological section observation process, pathologists have…

Medical Physics · Physics 2025-03-21 Yiyan Su , Ruiqing Sun , Yajing Wang , Yanfeng xi , Shaohui Zhang