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Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

Machine Learning · Computer Science 2025-05-02 Eloy Geenjaar , Vince Calhoun

Online sampling-supported visual analytics is increasingly important, as it allows users to explore large datasets with acceptable approximate answers at interactive rates. However, existing online spatiotemporal sampling techniques are…

Latent manifolds provide a compact characterization of neural population activity and of shared co-variability across brain areas. Nonetheless, existing statistical tools for extracting neural manifolds face limitations in terms of…

Neurons and Cognition · Quantitative Biology 2022-09-08 Edoardo Balzani , Jean Paul Noel , Pedro Herrero-Vidal , Dora E. Angelaki , Cristina Savin

We present a method for fast biomedical image atlas construction using neural fields. Atlases are key to biomedical image analysis tasks, yet conventional and deep network estimation methods remain time-intensive. In this preliminary work,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Zeen Chi , Zhongxiao Cong , Clinton J. Wang , Yingcheng Liu , Esra Abaci Turk , P. Ellen Grant , S. Mazdak Abulnaga , Polina Golland , Neel Dey

A prominent goal of neuroimaging studies is mapping the human brain, in order to identify and delineate functionally-meaningful regions and elucidate their roles in cognitive behaviors. These brain regions are typically represented by…

Human-Computer Interaction · Computer Science 2020-09-04 Roza G. Bayrak , Nhung Hoang , Colin B. Hansen , Catie Chang , Matthew Berger

The rapid expansion in the size of new datasets has created a need for fast and efficient parameter-learning techniques. Compressive learning is a framework that enables efficient processing by using random, non-linear features to project…

Machine Learning · Computer Science 2025-08-18 Daniel Mas Montserrat , David Bonet , Maria Perera , Xavier Giró-i-Nieto , Alexander G. Ioannidis

Current theories of perception suggest that the brain represents features of the world as probability distributions, but can such uncertain foundations provide the basis for everyday vision? Perceiving objects and scenes requires knowing…

Neurons and Cognition · Quantitative Biology 2022-11-30 Andrey Chetverikov , Árni Kristjánsson

The Allen Atlas of the adult mouse brain is a brain-wide, genome-wide data set that has been made available online, triggering a renaissance in neuroanatomy. In particular, it has been used to define brain regions in a computational,…

Neurons and Cognition · Quantitative Biology 2015-05-26 Pascal Grange

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Pattern extraction algorithms are enabling insights into the ever-growing amount of today's datasets by translating reoccurring data properties into compact representations. Yet, a practical problem arises: With increasing data volumes and…

Information Retrieval · Computer Science 2018-07-05 Michael Behrisch , Robert Krueger , Fritz Lekschas , Tobias Schreck , Nils Gehlenborg , Hanspeter Pfister

The Allen Atlas of the adult mouse brain is used to estimate the region-specificity of 64 cell types whose transcriptional profile in the mouse brain has been measured in microarray experiments. We systematically analyze the preliminary…

Neurons and Cognition · Quantitative Biology 2013-10-15 Pascal Grange , Michael Hawrylycz , Partha P. Mitra

The goal of this work is to develop principled techniques to extract information from high dimensional data sets with complex dependencies in areas such as medicine that can provide insight into individual as well as population level…

Gaussian graphical models are widely used to infer dependence structures. Bayesian methods are appealing to quantify uncertainty associated with structural learning, i.e., the plausibility of conditional independence statements given the…

Methodology · Statistics 2025-11-05 Deborah Sulem , Jack Jewson , David Rossell

Purpose: We propose a general framework for quantifying predictive uncertainties of dose-related quantities and leveraging this information in a dose mimicking problem in the context of automated radiation therapy treatment planning.…

Medical Physics · Physics 2021-09-08 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

Selecting relevant features is an important and necessary step for intelligent machines to maximize their chances of success. However, intelligent machines generally have no enough computing resources when faced with huge volume of data.…

Machine Learning · Computer Science 2025-07-04 Hexiang Bai , Deyu Li , Jiye Liang , Yanhui Zhai

An image pattern can be represented by a probability distribution whose density is concentrated on different low-dimensional subspaces in the high-dimensional image space. Such probability densities have an astronomical number of local…

Machine Learning · Statistics 2018-03-06 Mitch Hill , Erik Nijkamp , Song-Chun Zhu

This article presents a general Bayesian learning framework for multi-modal groupwise image registration. The method builds on probabilistic modelling of the image generative process, where the underlying common anatomy and geometric…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Xinzhe Luo , Xin Wang , Linda Shapiro , Chun Yuan , Jianfeng Feng , Xiahai Zhuang

We propose a unified framework for adaptive routing in multitask, multimodal prediction settings where data heterogeneity and task interactions vary across samples. Motivated by applications in psychotherapy where structured assessments and…

Federated learning and its application to medical image segmentation have recently become a popular research topic. This training paradigm suffers from statistical heterogeneity between participating institutions' local datasets, incurring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-19 Matthis Manthe , Stefan Duffner , Carole Lartizien

The Allen Brain Atlas (ABA) of the adult mouse consists of digitized expression profiles of thousands of genes in the mouse brain, co-registered to a common three-dimensional template (the Allen Reference Atlas). This brain-wide,…

Neurons and Cognition · Quantitative Biology 2015-10-28 Pascal Grange