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Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

Soft Condensed Matter · Physics 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

By analytically solving some simple models of phase-ordering kinetics, we suggest a mechanism for the onset of non-equilibrium behaviour in colloid-polymer mixtures. These mixtures can function as models of atomic systems; their physics…

Soft Condensed Matter · Physics 2016-08-31 R. M. L. Evans , W. C. K. Poon

A limited mobility nonequilibrium solid-on-solid dynamical model for kinetic surface growth is introduced as a simple description for the morphological evolution of a growing interface under random vapor deposition and surface diffusion…

Statistical Mechanics · Physics 2009-10-31 S. Das Sarma , P. Punyindu

Cell growth, division and death are defining features of biological tissues that contribute to morphogenesis. In hydrodynamic descriptions of cohesive tissues, their occurrence implies a non-zero rate of variation of cell density. We show…

Tissues and Organs · Quantitative Biology 2017-08-23 Shunsuke Yabunaka , Philippe Marcq

The space-time dynamics of rigid inhomogeneities (inclusions) free to move in a randomly fluctuating fluid bio-membrane is derived and numerically simulated as a function of the membrane shape changes. Both vertically placed (embedded)…

Computational Physics · Physics 2007-05-23 H. Rafii-Tabar , H. R. Sepangi

In this work, we present a phase-field model for tumour growth, where a diffuse interface separates a tumour from the surrounding host tissue. In our model, we consider transport processes by an internal, non-solenoidal velocity field. We…

Numerical Analysis · Mathematics 2024-06-21 Harald Garcke , Dennis Trautwein

Cells coexist together in colonies or as tissues. Their behaviour is controlled by an interplay between intercellular forces and biochemical regulation. We develop a simple model of the cell cycle, the fundamental regulatory network…

Biological Physics · Physics 2021-08-04 Jintao Li , Simon K. Schnyder , Matthew S. Turner , Ryoichi Yamamoto

We monitored isotropic spreading of mouse embryonic fibroblasts on fibronectin-coated substrates. Cell adhesion area versus time was measured via total internal reflection fluorescence microscopy. Spreading proceeds in well-defined phases.…

Cell Behavior · Quantitative Biology 2009-11-10 H. -G. Doebereiner , B. J. Dubin-Thaler , G. Giannone , H. S. Xenias , M. P. Sheetz

In this paper we present an individual-based mechanical model that describes the dynamics of two contiguous cell populations with different proliferative and mechanical characteristics. An off-lattice modelling approach is considered…

Analysis of PDEs · Mathematics 2020-01-14 Tommaso Lorenzi , Philip J. Murray , Mariya Ptashnyk

Tracking experiments in dense biological tissues reveal a diversity of sources f or local energy injection at the cell scale. The effect of cell motility has been largely studied, but much less is known abo ut the effect of the observed…

Soft Condensed Matter · Physics 2017-11-29 Elsen Tjhung , Ludovic Berthier

We investigate the dynamics of a colony of crawling, proliferating cells with a minimal, mechanical cell model. The cells consist of two disks, modelling the cell body and a pseudopod, connected by a finite extensible spring. The cells…

Cell Behavior · Quantitative Biology 2019-04-11 Simon K. Schnyder , John J. Molina , Ryoichi Yamamoto

This study develops an equation for describing three-dimensional membrane transformation through proliferation of its component cells regulated by morphogen density distributions on the membrane. The equation is developed in a…

Other Quantitative Biology · Quantitative Biology 2016-05-09 Hiroshi C. Ito

Frequently, the design of physicochemical processes requires screening of large numbers of alternative designs with complex geometries. These geometries may result in conformal meshes which introduce stability issues, significant…

Computational Physics · Physics 2021-01-19 E. J. Monte , J. Lowman , N. M. Abukhdeir

Liquid-liquid phase separation plays a major role in the formation and maintenance of various membrane-less subcellular structures in the cytoplasm and nucleus of cells. Biological condensates contain enhanced concentrations of proteins and…

Soft Condensed Matter · Physics 2023-10-03 Paul C Bressloff

We derive a phase field crystal model that couples the diffusive evolution of a microscopic structure with the fast dynamics of a macroscopic velocity field, explicitly accounting for the relaxation of elastic excitations. This model…

Materials Science · Physics 2022-10-26 Vidar Skogvoll , Marco Salvalaglio , Luiza Angheluta

The multi-phase-field approach is generalized to treat capillarity-driven diffusion parallel to the surfaces and phase-boundaries, i.e. the boundaries between a condensed phase and its vapor and the boundaries between two or multiple…

Mesoscale and Nanoscale Physics · Physics 2017-07-19 Raphael Schiedung , Reza Darvishi Kamachali , Ingo Steinbach , Fathollah Varnik

Multi-cell cooperative processing with limited backhaul traffic is studied for cellular uplinks. Aiming at reduced backhaul overhead, a sparsity-regularized multi-cell receive-filter design problem is formulated. Both unstructured…

Information Theory · Computer Science 2015-10-16 Swayambhoo Jain , Seung-Jun Kim , Georgios B. Giannakis

Elucidating versatile configurations of spiral folding, and investigating the deployment performance is of relevant interest to extend the applicability of deployable membranes towards large-scale and functional configurations. In this…

Soft Condensed Matter · Physics 2020-12-11 Victor Parque , Wataru Suzaki , Satoshi Miura , Ayako Torisaka , Tomoyuki Miyashita , Michihiro Natori

Tissue fluidity regulates many critical biological processes, including embryonic development, wound healing, and cancer metastasis. In confluent epithelia, where cell packing fraction is effectively fixed, the prevailing paradigm…

Biological Physics · Physics 2026-03-09 Pradip K. Bera , Anh Q. Nguyen , Molly McCord , Dapeng Bi , Jacob Notbohm

Letting free polymers diffuse from solution into a crosslinked polymer gel is often a crucial processing step in the synthesis of multiphase polymer-based gels, e.g., core-shell microgels. Here we use coarse-grained molecular dynamics…

Soft Condensed Matter · Physics 2024-12-17 Jude Ann Vishnu , Torsten Gereon Linder , Sebastian Seiffert , Friederike Schmid
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