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Motivation: The comparison of diverse genomic datasets is fundamental to understanding genome biology. Researchers must explore many large datasets of genome intervals (e.g., genes, sequence alignments) to place their experimental results…

Genomics · Quantitative Biology 2012-08-20 Ryan M. Layer , Kevin Skadron , Gabriel Robins , Ira M. Hall , Aaron R. Quinlan

Retrieval-augmented generation (RAG) improves the response quality of large language models (LLMs) by retrieving knowledge from external databases. Typical RAG approaches split the text database into chunks, organizing them in a flat…

Computation and Language · Computer Science 2025-11-18 Boyu Chen , Zirui Guo , Zidan Yang , Yuluo Chen , Junze Chen , Zhenghao Liu , Chuan Shi , Cheng Yang

Ren et al. recently introduced a method for aggregating multiple decision trees into a strong predictor by interpreting a path taken by a sample down each tree as a binary vector and performing linear regression on top of these vectors…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Nenad Markuš , Ivan Gogić , Igor S. Pandžić , Jörgen Ahlberg

Scaling regression to large datasets is a common problem in many application areas. We propose a two step approach to scaling regression to large datasets. Using a regression tree (CART) to segment the large dataset constitutes the first…

Machine Learning · Statistics 2017-07-26 Rajiv Sambasivan , Sourish Das

Code completion, a crucial practice in industrial settings, helps developers improve programming efficiency by automatically suggesting code snippets during development. With the emergence of Large Code Models (LCMs), this field has…

Software Engineering · Computer Science 2025-05-22 Chaozheng Wang , Zezhou Yang , Shuzheng Gao , Cuiyun Gao , Ting Peng , Hailiang Huang , Yuetang Deng , Michael Lyu

Large language models (LLMs) have rapidly advanced and demonstrated impressive capabilities. In-Context Learning (ICL) and Parameter-Efficient Fine-Tuning (PEFT) are currently two mainstream methods for augmenting LLMs to downstream tasks.…

Computation and Language · Computer Science 2024-11-21 Luohe Shi , Yao Yao , Zuchao Li , Lefei Zhang , Hai Zhao

Purpose: Large Language Models (LLMs) hold significant promise for medical applications. Retrieval Augmented Generation (RAG) emerges as a promising approach for customizing domain knowledge in LLMs. This case study presents the development…

We investigate the exploitation of both lexical and neural relevance signals for ad-hoc passage retrieval. Our exploration involves a large-scale training dataset in which dense neural representations of MS-MARCO queries and passages are…

Information Retrieval · Computer Science 2025-10-21 Franco Maria Nardini , Raffaele Perego , Nicola Tonellotto , Salvatore Trani

Retrieval-Augmented Generation (RAG) has demonstrated significant effectiveness in enhancing large language models (LLMs) for complex multi-hop question answering (QA). For multi-hop QA tasks, current iterative approaches predominantly rely…

Computation and Language · Computer Science 2026-01-19 Yuling Shi , Maolin Sun , Zijun Liu , Mo Yang , Yixiong Fang , Tianran Sun , Xiaodong Gu

Long text classification is challenging for Large Language Models (LLMs) due to token limits and high computational costs. This study explores whether a Retrieval Augmented Generation (RAG) approach using only the most relevant text…

We perform experimental studies on data structures that answer path median, path counting, and path reporting queries in weighted trees. These query problems generalize the well-known range median query problem in arrays, as well as the…

Data Structures and Algorithms · Computer Science 2020-04-21 Meng He , Serikzhan Kazi

Recently, deep convolutional neural networks have achieved great success for medical image segmentation. However, unlike segmentation of natural images, most medical images such as MRI and CT are volumetric data. In order to make full use…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Yichi Zhang , Qingcheng Liao , Le Ding , Jicong Zhang

Semantic segmentation of medical images is an essential first step in computer-aided diagnosis systems for many applications. However, given many disparate imaging modalities and inherent variations in the patient data, it is difficult to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Bhavani Sambaturu , Ashutosh Gupta , C. V. Jawahar , Chetan Arora

Histograms are used to summarize the contents of relations into a number of buckets for the estimation of query result sizes. Several techniques (e.g., MaxDiff and V-Optimal) have been proposed in the past for determining bucket boundaries…

Data Structures and Algorithms · Computer Science 2007-05-23 Francesco Buccafurri , Gianluca Lax , Domenico Sacca' , Luigi Pontieri , Domenico Rosaci

Retrieval-Augmented Generation (RAG) offers a well-established path to grounding large language model (LLM) outputs in external knowledge, yet the question of which retrieval strategy works best in a high-stakes domain such as biomedicine…

Computation and Language · Computer Science 2026-05-05 Devi Prasad Bal , Subhashree Puhan

Random forests (RFs) are among the most popular supervised learning algorithms due to their nonlinear flexibility and ease-of-use. However, as black box models, they can only be interpreted via algorithmically-defined feature importance…

Methodology · Statistics 2025-05-26 Abhineet Agarwal , Ana M. Kenney , Yan Shuo Tan , Tiffany M. Tang , Bin Yu

Deep learning models are being adopted and applied on various critical decision-making tasks, yet they are trained to provide point predictions without providing degrees of confidence. The trustworthiness of deep learning models can be…

Machine Learning · Computer Science 2024-10-28 Daniel Nolte , Souparno Ghosh , Ranadip Pal

To explain individual differences in development, behavior, and cognition, most previous studies focused on projecting resting-state functional MRI (fMRI) based functional connectivity (FC) data into a low-dimensional space via linear…

Neurons and Cognition · Quantitative Biology 2018-11-01 Li Xiao , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

The ability to plan ahead efficiently is key for both living organisms and artificial systems. Model-based planning and prospection are widely studied in cognitive neuroscience and artificial intelligence (AI), but from different…

Artificial Intelligence · Computer Science 2026-01-30 Domenico Maisto , Francesco Gregoretti , Karl Friston , Giovanni Pezzulo

Approximate nearest neighbor (ANN) search with range filters has recently garnered significant attention. This paper delves into a generalized form of this problem, i.e., ANN search with exact range-range (RR) predicates on a range-valued…

Databases · Computer Science 2026-05-27 Yingfan Liu , Tong Wu , Jiadong Xie , Yang Zhao , Jeffrey Xu Yu , Jiangtao Cui