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With the maturation of differentiable physics, its role in various downstream applications: such as model predictive control, robotic design optimization, and neural PDE solvers, has become increasingly important. However, the derivative…

Robotics · Computer Science 2025-09-26 Xiaohan Ye , Kui Wu , Zherong Pan , Taku Komura

Thanks to recent technological advances, it is now possible to track with an unprecedented precision and for long periods of time the movement patterns of many living organisms in their habitat. The increasing amount of data available on…

Populations and Evolution · Quantitative Biology 2015-05-19 Denis Boyer , Peter D. Walsh

Biological cells sense and respond to mechanical forces, but how such a mechanosensing proccess takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show that cells in a fibrous matrix induce deformation fields that…

Biological Physics · Physics 2015-06-10 Jacob Notbohm , Ayelet Lesman , Phoebus Rosakis , David A. Tirrell , Guruswami Ravichandran

Cell tracking and segmentation assist biologists in extracting insights from large-scale microscopy time-lapse data. Driven by local accuracy metrics, current tracking approaches often suffer from a lack of long-term consistency and the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Timo Kaiser , Maximilian Schier , Bodo Rosenhahn

The behaviour and fate of tissue cells is controlled by the rigidity and geometry of their adhesive environment, possibly through forces localized to sites of adhesion. We introduce a mechanical model that predicts cellular force…

Cell Behavior · Quantitative Biology 2009-07-24 Ilka B. Bischofs , Sebastian S. Schmidt , Ulrich S. Schwarz

Living cells are capable of interacting with their environments in a variety of ways, including cell signalling, adhesion, and directed motion. These behaviours are often mediated by receptor molecules embedded in the cell membrane, which…

Biological Physics · Physics 2023-10-17 Hannah Sleath , Bortolo Mognetti , Yuval Elani , Lorenzo Di Michele

We investigate the dynamic relaxation of random walks on temporal networks by focusing in the recently proposed activity driven model [Perra \textit{et al.} Sci. Rep. srep00469 (2012)]. For realistic activity distributions with a power-law…

Statistical Mechanics · Physics 2014-11-18 Angélica S. Mata , Romualdo Pastor-Satorras

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

Biological Physics · Physics 2022-07-13 T. N. Azevedo , L. G. Rizzi

The migratory dynamics of cells can be influenced by the complex micro-environment through which they move. It remains unclear how the motility machinery of confined cells responds and adapts to their micro-environment. Here, we propose a…

Biological Physics · Physics 2023-12-04 Johannes Flommersfeld , Stefan Stöberl , Omar Shah , Joachim O. Rädler , Chase P. Broedersz

We present a model for a random walk with memory, phenomenologically inspired in a biological system. The walker has the capacity to remember the time of the last visit to each site and the step taken from there. This memory affects the…

Adaptation and Self-Organizing Systems · Physics 2015-01-15 Laila D. Kazimierski , Guillermo Abramson , Marcelo N. Kuperman

The more we learn about the cytoplasm of cells, the more we realise that the cytoplasm is not uniform but instead is highly inhomogeneous. In any inhomogeneous solution, there are concentration gradients, and particles move either up or…

Subcellular Processes · Quantitative Biology 2019-04-03 Richard P. Sear

Inhomogeneities in deposition may lead to formation of rough surfaces, whose height fluctuations can be probed directly by scanning microscopy, or indirectly by scattering. Analytical or numerical treatments of simple growth models suggest…

Condensed Matter · Physics 2009-10-28 Mehran Kardar

DNA and other biopolymers differ from classical polymers due to their torsional stiffness. This property changes the statistical character of their conformations under tension from a classical random walk to a problem we call the `torsional…

Soft Condensed Matter · Physics 2009-10-30 J. David Moroz , Philip Nelson

In this paper, we explore the reduction of functionality in a complex system as a consequence of cumulative random damage and imperfect reparation, a phenomenon modeled as a dynamical process on networks. We analyze the global…

Statistical Mechanics · Physics 2021-06-07 L. K. Eraso-Hernandez , A. P. Riascos , T. M. Michelitsch , J. Wang-Michelitsch

Collective cell motions underlie structure formation during embryonic development. Tissues exhibit emergent multicellular characteristics such as jamming, rigidity transitions, and glassy dynamics, but there remain questions about how those…

Biological Physics · Physics 2023-12-13 Evan Thomas , Sevan Hopyan

In multi-cellular organisms, cells differentiate into multiple types as they divide. States of these cell types, as well as their numbers, are known to be robust to external perturbations; as conceptualized by Waddington's epigenetic…

Biological Physics · Physics 2026-01-21 Davey Plugers , Kunihiko Kaneko

We study a simple model in which the growth of a network is determined by the location of one or more random walkers. Depending on walker speed, the model generates a spectrum of structures situated between well-known limiting cases. We…

Physics and Society · Physics 2020-01-27 Robert J. H. Ross , Charlotte Strandkvist , Walter Fontana

Here, we study the coalescence of two droplets that are moving in the same direction on a soft surface; the motion of the droplets is caused by a gradient in the surface stiffness. As reference, stationary coalescence of the same droplets…

Soft Condensed Matter · Physics 2026-05-19 Divyansh Tripathi , Vimal Kishore , Panagiotis E. Theodorakis , Swarn Lata Singh

Driven particles in presence of crowded environment, obstacles or kinetic constraints often exhibit negative differential mobility (NDM) due to their decreased dynamical activity. We propose a new mechanism for complex many-particle systems…

Statistical Mechanics · Physics 2018-06-06 Amit Kumar Chatterjee , Urna Basu , P. K. Mohanty

A lattice walk model is said to be reluctant if the defining step set has a strong drift towards the boundaries. We describe efficient random generation strategies for these walks.

Combinatorics · Mathematics 2016-03-22 Jeremie Lumbroso , Marni Mishna , Yann Ponty