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Given hydric capacity and nutrient flow of a chemostat-like system, we analyse the influence of a spatial structure on the output concentrations at steady-state. Three configurations are compared: perfectly-mixed, serial and parallel with…

Dynamical Systems · Mathematics 2010-11-17 Alain Rapaport , Ihab Haidar

Most evolutionary algorithms have parameters, which allow a great flexibility in controlling their behavior and adapting them to new problems. To achieve the best performance, it is often needed to control some of the parameters during…

Neural and Evolutionary Computing · Computer Science 2021-06-07 Maxim Buzdalov , Carola Doerr

A discrete chemotactic predator-prey model is proposed in which the prey secrets a diffusing chemical which is sensed by the predator and vice versa. Two dynamical states corresponding to catching and escaping are identified and it is shown…

Populations and Evolution · Quantitative Biology 2015-05-20 Ankush Sengupta , Tobias Kruppa , Hartmut Löwen

We study a stochastic differential equation driven by a Poisson point process, which models continuous changes in a population's environment, as well as the stochastic fixation of beneficial mutations that might compensate for this change.…

Probability · Mathematics 2017-07-21 Elma Nassar , Etienne Pardoux

What is motivation and how does it work? Where do goals come from and how do they vary within and between species and individuals? Why do we prefer some things over others? MEDO is a theoretical framework for understanding these questions…

Neurons and Cognition · Quantitative Biology 2019-11-12 Adam Safron

Distribution shifts have long been regarded as troublesome external forces that a decision-maker should either counteract or conform to. An intriguing feedback phenomenon termed decision dependence arises when the deployed decision affects…

Optimization and Control · Mathematics 2025-03-11 Zhiyu He , Saverio Bolognani , Florian Dörfler , Michael Muehlebach

The performance of an algorithm often critically depends on its parameter configuration. While a variety of automated algorithm configuration methods have been proposed to relieve users from the tedious and error-prone task of manually…

Artificial Intelligence · Computer Science 2022-05-30 Steven Adriaensen , André Biedenkapp , Gresa Shala , Noor Awad , Theresa Eimer , Marius Lindauer , Frank Hutter

The design space of networked embedded systems is very large, posing challenges to the optimisation of such platforms when it comes to support applications with real-time guarantees. Recent research has shown that a number of inter-related…

Performance · Computer Science 2020-07-21 Leandro Soares Indrusiak , Robert I. Davis , Piotr Dziurzanski

We investigate the mutation-selection dynamics for an evolutionary computation model based on Turing Machines that we introduced in a previous article. The use of Turing Machines allows for very simple mechanisms of code growth and code…

Populations and Evolution · Quantitative Biology 2015-03-17 Fabio Musso , Giovanni Feverati

Resource-intensive computations are a major factor that limits the effectiveness of automated machine learning solutions. In the paper, we propose a modular approach that can be used to increase the quality of evolutionary optimization for…

Machine Learning · Computer Science 2023-01-13 Nikolay O. Nikitin , Sergey Teryoshkin , Valerii Pokrovskii , Sergey Pakulin , Denis Nasonov

In recent decades, cold atom experiments have become increasingly complex. While computers control most parameters, optimization is mostly done manually. This is a time-consuming task for a high-dimensional parameter space with unknown…

Quantum Physics · Physics 2013-09-03 I. Geisel , K. Cordes , J. Mahnke , S. Jöllenbeck , J. Ostermann , J. Arlt , W. Ertmer , C. Klempt

Accurate control of quantum systems requires precise measurement of the parameters that govern the dynamics, including control fields and interactions with the environment. Parameters will drift in time and experiments interleave protocols…

Quantum Physics · Physics 2020-02-11 Swarnadeep Majumder , Leonardo Andreta de Castro , Kenneth R. Brown

Traditional VMAT optimization often ignores dynamic machine limits, treating delivery time as an emergent property rather than a steerable parameter. This work introduces Dynamic Modulated Arc Therapy (DMAT), an intent-driven framework that…

This paper introduces a variational formulation of natural selection, paying special attention to the nature of "things" and the way that different "kinds" of "things" are individuated from - and influence - each other. We use the Bayesian…

Populations and Evolution · Quantitative Biology 2023-07-05 Karl Friston , Daniel Ari Friedman , Axel Constant , V. Bleu Knight , Thomas Parr , John O. Campbell

In this paper, we study the global dynamics of a chemostat model with a single nutrient and several competing species. Growth rates are not required to be proportional to food uptakes. The model was studied by Fiedler and Hsu [J. Math.…

Dynamical Systems · Mathematics 2011-07-29 Tewfik Sari

Synthetic microbiomes offer new possibilities for modulating microbiota, to address the barriers in multidtug resistance (MDR) research. We present a Bayesian optimization approach to enable efficient searching over the space of synthetic…

Quantitative Methods · Quantitative Biology 2024-05-02 Nisha Pillai , Bindu Nanduri , Michael J Rothrock , Zhiqian Chen , Mahalingam Ramkumar

The research area of evolutionary multiobjective optimization (EMO) is reaching better understandings of the properties and capabilities of EMO algorithms, and accumulating much evidence of their worth in practical scenarios. An urgent…

Neural and Evolutionary Computing · Computer Science 2009-08-24 David Corne , Joshua Knowles

A molecular understanding of how protein function is related to protein structure will require an ability to understand large conformational changes between multiple states. Unfortunately these states are often separated by high free energy…

Biological Physics · Physics 2011-08-08 Juan R. Perilla , Thomas B. Woolf

The evolution and emergence of antibiotic resistance is a major public health concern. The understanding of the within-host microbial dynamics combining mutational processes, horizontal gene transfer and resource consumption, is one of the…

Populations and Evolution · Quantitative Biology 2020-03-09 Ramsès Djidjou-Demasse , Samuel Alizon , Mircea T. Sofonea

In this paper, we develop a two-stage data-driven approach to address the adjustable robust optimization problem, where the uncertainty set is adjustable to manage infeasibility caused by significant or poorly quantified uncertainties. In…

Optimization and Control · Mathematics 2025-05-29 Xiaoxing Ren , Alessio Moreschini , Zhongda Chu , Yulong Gao , Thomas Parisini