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Molecular phenotypes link genomic information with organismic functions, fitness, and evolution. Quantitative traits are complex phenotypes that depend on multiple genomic loci. In this paper, we study the adaptive evolution of a…

Populations and Evolution · Quantitative Biology 2015-06-19 Torsten Held , Armita Nourmohammad , Michael Lässig

We propose a class of evolutionary models that involves an arbitrary exchangeable process as the breeding process and different selection schemes. In those models, a new genome is born according to the breeding process, and then a genome is…

Neural and Evolutionary Computing · Computer Science 2020-08-25 Jüri Lember , Chris Watkins

The population dynamics that evolves in the radial symmetric geometry is investigated. The nonlinear reaction-diffusion model, which depends on population density, is employed as the governing equation for this system. The approximate…

Biological Physics · Physics 2014-01-17 Waipot Ngamsaad

Existing theoretical models of evolution focus on the relative fitness advantages of different mutants in a population while the dynamic behavior of the population size is mostly left unconsidered. We here present a generic stochastic model…

Populations and Evolution · Quantitative Biology 2010-10-20 Anna Melbinger , Jonas Cremer , Erwin Frey

Continuous-time branching processes describe the evolution of a population whose individuals generate a random number of children according to a birth process. Such branching processes can be used to understand preferential attachment…

Probability · Mathematics 2017-11-10 Alessandro Garavaglia , Remco van der Hofstad , Gerhard Woeginger

The progression of a cell population where each individual is characterized by the value of an internal variable varying with time (e.g. size, weight, and protein concentration) is typically modeled by a Population Balance Equation, a first…

Cell Behavior · Quantitative Biology 2016-04-20 Qasim Ali , Ali Elkamel , Frédéric Gruy , Claude Lambert , Eric Touboul

Recent evidence suggests that nongenetic (epigenetic) mechanisms play an important role at all stages of cancer evolution. In many cancers, these mechanisms have been observed to induce dynamic switching between two or more cell states,…

Quantitative Methods · Quantitative Biology 2023-06-16 Einar Bjarki Gunnarsson , Jasmine Foo , Kevin Leder

Predicting the adaptation of populations to a changing environment is crucial to assess the impact of human activities on biodiversity. Many theoretical studies have tackled this issue by modeling the evolution of quantitative traits…

Analysis of PDEs · Mathematics 2022-06-28 Jimmy Garnier , O Cotto , T Bourgeron , E Bouin , T Lepoutre , O Ronce , V Calvez

Starting with Darwin, biologists have asked how populations evolve from a low fitness state that is evolutionarily stable to a high fitness state that is not. Specifically of interest is the emergence of cooperation and multicellularity…

Populations and Evolution · Quantitative Biology 2015-11-10 Dervis Can Vural , Alexander Isakov , L. Mahadevan

We consider an exponentially growing population of cells undergoing mutations and ask about the effect of reproductive fluctuations (genetic drift) on its long-term evolution. We combine first step analysis with the stochastic dynamics of a…

Populations and Evolution · Quantitative Biology 2022-03-14 Arman Angaji , Christoph Velling , Johannes Berg

How are granular details of stochastic growth and division of individual cells reflected in smooth deterministic growth of population numbers? We provide an integrated, multiscale perspective of microbial growth dynamics by formulating a…

In this paper we study collective decision making on a multi-population, represented by a regular network of groups of individuals. Each group consists of a collection of players and every player can choose between two options. A group is…

Optimization and Control · Mathematics 2020-11-18 Wouter Baar , Dario Bauso

In exponentially proliferating populations of microbes, the population typically doubles at a rate less than the average doubling time of a single-cell due to variability at the single-cell level. It is known that the distribution of…

Populations and Evolution · Quantitative Biology 2020-07-29 Ethan Levien , Trevor GrandPre , Ariel Amir

Understanding the evolutionary dynamics of reinforcement learning under multi-agent settings has long remained an open problem. While previous works primarily focus on 2-player games, we consider population games, which model the strategic…

Multiagent Systems · Computer Science 2020-06-30 Shuyue Hu , Chin-Wing Leung , Ho-fung Leung , Harold Soh

This article presents a comprehensive study of the continuous McKendrick model, which serves as a foundational framework in population dynamics and epidemiology. The model is formulated through partial differential equations that describe…

Populations and Evolution · Quantitative Biology 2026-01-23 Dragos-Patru Covei

Understanding the relationship between population and the built environment is essential for addresing socio-spatial inequalities. While researchers have long theorized these dynamics, empirical analyses remain limited. This study develops…

Computers and Society · Computer Science 2026-03-12 Anna Brazdova , Martin Fleischmann

Cell size is a fundamental determinant of cellular physiology, influencing processes such as growth, division, and function. In this study, we develop a segmented mathematical framework to investigate how different control mechanisms…

Cell Behavior · Quantitative Biology 2026-02-02 Shuqi Fan , Yuhang Zhang , Jinzhi Lei

We introduce a population-age-time (PAT) model which describes the temporal evolution of the population distribution in age. The surprising result is that the qualitative nature of the population distribution dynamics is robust with respect…

Populations and Evolution · Quantitative Biology 2021-11-30 Z. C. Feng , Y. Charles Li

Age dependent population dynamics are frequently modeled with generalizations of the classic McKendrick-von Foerster equation. These are deterministic systems, and a stochastic generalization was recently reported in [1,2]. Here we develop…

Biological Physics · Physics 2016-11-21 Chris D Greenman

Concerns about biodiversity and the long-term stability of forest ecosystems have lead to changing attitudes with respect to plantations. These artificial communities are ubiquitous, yet provide reduced habitat value in comparison to their…

Populations and Evolution · Quantitative Biology 2009-10-05 Tom Adams , Graeme Ackland , Glenn Marion , Colin Edwards