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Quantitative Susceptibility Mapping (QSM) dipole inversion is an ill-posed inverse problem for quantifying magnetic susceptibility distributions from MRI tissue phases. While supervised deep learning methods have shown success in specific…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Zhuang Xiong , Wei Jiang , Yang Gao , Feng Liu , Hongfu Sun

Deep neural networks have demonstrated promising potential for the field of medical image reconstruction. In this work, an MRI reconstruction algorithm, which is referred to as quantitative susceptibility mapping (QSM), has been developed…

Image and Video Processing · Electrical Eng. & Systems 2018-06-18 Jaeyeon Yoon , Enhao Gong , Itthi Chatnuntawech , Berkin Bilgic , Jingu Lee , Woojin Jung , Jingyu Ko , Hosan Jung , Kawin Setsompop , Greg Zaharchuk , Eung Yeop Kim , John Pauly , Jongho Lee

In the human brain, essential iron molecules for proper neurological functioning exist in transferrin (tf) and ferritin (Fe3) forms. However, its unusual increment manifests iron overload, which reacts with hydrogen peroxide. This reaction…

Neurons and Cognition · Quantitative Biology 2022-11-10 Shradha Verma , Tripti Goel , M Tanveer

Quantitative susceptibility mapping (QSM) is a useful magnetic resonance imaging (MRI) technique which provides spatial distribution of magnetic susceptibility values of tissues. QSMs can be obtained by deconvolving the dipole kernel from…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Gyutaek Oh , Hyokyoung Bae , Hyun-Seo Ahn , Sung-Hong Park , Jong Chul Ye

Artifacts in quantitative susceptibility mapping (QSM) are analyzed to establish an optimal design criterion for QSM inversion algorithms. The magnetic field data is decomposed into two parts, dipole compatible and incompatible parts. The…

Medical Physics · Physics 2017-01-20 Liangdong Zhou , Jae Kyu Choi , Youngwook Kee , Yi Wang , Jin Keun Seo

Quantitative susceptibility mapping (QSM) inevitably suffers from streaking artifacts caused by zeros on the conical surface of the dipole kernel in k-space. This work proposes a novel and accurate QSM reconstruction method based on a…

Computer Vision and Pattern Recognition · Computer Science 2019-10-16 Hyun-Seo Ahn , Sung-Hong Park , Jong Chul Ye

Quantitative Susceptibility Mapping (QSM) estimates tissue magnetic susceptibility distributions from Magnetic Resonance (MR) phase measurements by solving an ill-posed dipole inversion problem. Conventional single orientation QSM methods…

Image and Video Processing · Electrical Eng. & Systems 2020-08-13 Kuo-Wei Lai , Manisha Aggarwal , Peter van Zijl , Xu Li , Jeremias Sulam

Introduction: Quantitative Susceptibility Mapping (QSM) is generally acquired with full brain coverage, even though many QSM brain-iron studies focus on the deep grey matter (DGM) region only. Reducing the spatial coverage to the DGM…

Quantitative Methods · Quantitative Biology 2021-06-02 Xuanyu Zhu , Yang Gao , Feng Liu , Stuart Crozier , Hongfu Sun

Quantitative Susceptibility Mapping is a parametric imaging technique to estimate the magnetic susceptibilities of biological tissues from MRI phase measurements. This problem of estimating the susceptibility map is ill posed. Regularized…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Arvind Balachandrasekaran , Davood Karimi , Camilo Jaimes , Ali Gholipour

Quantitative susceptibility mapping (QSM) utilizes MRI phase information to estimate tissue magnetic susceptibility. The generation of QSM requires solving ill-posed background field removal (BFR) and field-to-source inversion problems.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Juan Liu , Kevin M Koch

Quantitative susceptibility mapping (QSM) is a valuable MRI post-processing technique that quantifies the magnetic susceptibility of body tissue from phase data. However, the traditional QSM reconstruction pipeline involves multiple…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Yang Gao , Zhuang Xiong , Amir Fazlollahi , Peter J Nestor , Viktor Vegh , Fatima Nasrallah , Craig Winter , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Deep learning based Quantitative Susceptibility Mapping (QSM) has shown great potential in recent years, obtaining similar results to established non-learning approaches. Many current deep learning approaches are not data consistent,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Francesco Cognolato , Kieran O'Brien , Jin Jin , Simon Robinson , Frederik B. Laun , Markus Barth , Steffen Bollmann

Purpose: For quantitative susceptibility mapping (QSM), the lack of ground-truth in clinical settings makes it challenging to determine suitable parameters for the dipole inversion. We propose a probabilistic Bayesian approach for QSM with…

Image and Video Processing · Electrical Eng. & Systems 2023-06-01 Shuai Huang , James J. Lah , Jason W. Allen , Deqiang Qiu

Purpose: Field-to-susceptibility inversion in quantitative susceptibility mapping (QSM) is ill-posed and needs numerical stabilization through either regularization or oversampling by acquiring data at three or more object orientations.…

Quantitative susceptibility mapping (QSM) provides a valuable tool for quantifying susceptibility distributions in human brains; however, two types of opposing susceptibility sources (i.e., paramagnetic and diamagnetic), may coexist in a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Min Li , Chen Chen , Zhenghao Li , Yin Liu , Shanshan Shan , Peng Wu , Pengfei Rong , Feng Liu , G. Bruce Pike , Alan H. Wilman , Hongfu Sun , Yang Gao

Purpose: To improve repeatability and reproducibility across acquisition parameters and reduce bias in quantitative susceptibility mapping (QSM) of the liver, through development of an optimized regularized reconstruction algorithm for…

Inverse problems are ubiquitous in modern scientific studies and involve recovering an underlying signal from noisy observations often transformed by a measurement operator. These problems are frequently ill-posed, particularly in imaging,…

Methodology · Statistics 2026-05-19 Henry J. Aldridge , Tobías I. Liaudat , Marcelo Pereyra , Jason D. McEwen

Quantitative magnetic resonance imaging (qMRI) offers tissue-specific physical parameters with significant potential for neuroscience research and clinical practice. However, lengthy scan times for 3D multiparametric qMRI acquisition limit…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Guoyan Lao , Ruimin Feng , Haikun Qi , Zhenfeng Lv , Qiangqiang Liu , Chunlei Liu , Yuyao Zhang , Hongjiang Wei

The worst-case robust adaptive beamforming problem for general-rank signal model is considered. This is a nonconvex problem, and an approximate version of it (obtained by introducing a matrix decomposition on the presumed covariance matrix…

Signal Processing · Electrical Eng. & Systems 2021-09-21 Yongwei Huang , Sergiy A. Vorobyov , Zhi-Quan Luo

Quantitative susceptibility mapping (QSM) has demonstrated great potential in quantifying tissue susceptibility in various brain diseases. However, the intrinsic ill-posed inverse problem relating the tissue phase to the underlying…

Computer Vision and Pattern Recognition · Computer Science 2021-05-21 Ruimin Feng , Jiayi Zhao , He Wang , Baofeng Yang , Jie Feng , Yuting Shi , Ming Zhang , Chunlei Liu , Yuyao Zhang , Jie Zhuang , Hongjiang Wei