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Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Ping-Chang Lin , Teodora Szasz , Hakizumwami B. Runesha

Neural networks have recently been established as a viable classification method for imaging mass spectrometry data for tumor typing. For multi-laboratory scenarios however, certain confounding factors may strongly impede their performance.…

The convolutional neural network (CNN) has become a powerful tool for various biomedical image analysis tasks, but there is a lack of visual explanation for the machinery of CNNs. In this paper, we present a novel algorithm,…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Guannan Zhao , Bo Zhou , Kaiwen Wang , Rui Jiang , Min Xu

A major prerequisite for the application of machine learning models in clinical decision making is trust and interpretability. Current explainability studies in the neuroimaging community have mostly focused on explaining individual…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Fabian Eitel , Anna Melkonyan , Kerstin Ritter

Computer aided detection and diagnosis systems based on deep learning have shown promising performance in breast cancer detection. However, there are cases where the obtained results lack justification. In this study, our objective is to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Imane Nedjar , Mohammed Brahimi , Said Mahmoudi , Khadidja Abi Ayad , Mohammed Amine Chikh

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

Deep learning has achieved expert-level performance in automated electrocardiogram (ECG) diagnosis, yet the "black-box" nature of these models hinders their clinical deployment. Trust in medical AI requires not just high accuracy but also…

Machine Learning · Computer Science 2026-02-11 Vajira Thambawita , Jonas L. Isaksen , Jørgen K. Kanters , Hugo L. Hammer , Pål Halvorsen

Deep neural networks (DNNs) show promise in breast cancer screening, but their robustness to input perturbations must be better understood before they can be clinically implemented. There exists extensive literature on this subject in the…

Representations in the hidden layers of Deep Neural Networks (DNN) are often hard to interpret since it is difficult to project them into an interpretable domain. Graph Convolutional Networks (GCN) allow this projection, but existing…

Computation and Language · Computer Science 2019-09-25 Robert Schwarzenberg , Marc Hübner , David Harbecke , Christoph Alt , Leonhard Hennig

Although deep learning models are powerful among various applications, most deep learning models are still a black box, lacking verifiability and interpretability, which means the decision-making process that human beings cannot understand.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Qianmengke Zhao , Ye Wang , Qun Liu

Deep Convolutional Neural Networks (CNN) provides an "end-to-end" solution for image pattern recognition with impressive performance in many areas of application including medical imaging. Most CNN models of high performance use…

Image and Video Processing · Electrical Eng. & Systems 2020-05-29 Mohammed Ahmed , Hongbo Du , Alaa AlZoubi

Modern cosmological research in large scale structure has witnessed an increasing number of applications of machine learning methods. Among them, Convolutional Neural Networks (CNNs) have received substantial attention due to their…

Cosmology and Nongalactic Astrophysics · Physics 2024-02-16 Zhengyangguang Gong , Anik Halder , Annabelle Bohrdt , Stella Seitz , David Gebauer

Deep convolutional neural networks (CNNs) have achieved breakthrough performance in many pattern recognition tasks such as image classification. However, the development of high-quality deep models typically relies on a substantial amount…

Computer Vision and Pattern Recognition · Computer Science 2016-05-05 Mengchen Liu , Jiaxin Shi , Zhen Li , Chongxuan Li , Jun Zhu , Shixia Liu

Convolutional neural networks (CNNs) have shown exceptional performance for a range of medical imaging tasks. However, conventional CNNs are not able to explain their reasoning process, therefore limiting their adoption in clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Linde S. Hesse , Ana I. L. Namburete

Recent advances in deep learning have enabled the development of automated frameworks for analysing medical images and signals, including analysis of cervical cancer. Many previous works focus on the analysis of isolated cervical cells, or…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Ruiqi Wang , Mohammad Ali Armin , Simon Denman , Lars Petersson , David Ahmedt-Aristizabal

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

This paper presents a tutorial of an explainable approach using Convolutional Neural Network (CNN) and Gradient-weighted Class Activation Mapping (Grad-CAM) to classify four progressive dementia stages based on open MRI brain images. The…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Kevin Kam Fung Yuen

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

The perceptual-based grouping process produces a hierarchical and compositional image representation that helps both human and machine vision systems recognize heterogeneous visual concepts. Examples can be found in the classical…

Computer Vision and Pattern Recognition · Computer Science 2020-03-27 Zhiheng Li , Wenxuan Bao , Jiayang Zheng , Chenliang Xu

A recent study on the interpretability of real-valued convolutional neural networks (CNNs) {Stankovic_Mandic_2023CNN} has revealed a direct and physically meaningful link with the task of finding features in data through matched filters.…

Machine Learning · Computer Science 2024-02-01 Qingchen Wang , Zhe Li , Zdenka Babic , Wei Deng , Ljubiša Stanković , Danilo P. Mandic