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Accurate prediction of materials phase diagrams from first principles remains a central challenge in computational materials science. Machine-learning interatomic potentials can provide near-DFT accuracy at a fraction of the cost, but their…

Materials Science · Physics 2026-02-23 Nico Unglert , Michael Ketter , Georg K. H. Madsen

Reactive force fields for molecular dynamics have enabled a wide range of studies in numerous material classes. These force fields are computationally inexpensive as compared to electronic structure calculations and allow for simulations of…

Materials Science · Physics 2023-04-26 Brenden W. Hamilton , Pilsun Yoo , Michael N. Sakano , Md Mahbubul Islam , Alejandro Strachan

Machine Learning techniques can be used to represent high-dimensional potential energy surfaces for reactive chemical systems. Two such methods are based on a reproducing kernel Hilbert space representation or on deep neural networks. They…

Chemical Physics · Physics 2019-09-19 Oliver T. Unke , Markus Meuwly

We have generated an open-source dataset of over 30000 organic chemistry gas phase partition functions. With this data, a machine learning deep neural network estimator was trained to predict partition functions of unknown organic chemistry…

Chemical Physics · Physics 2022-03-08 Evan Komp , Stéphanie Valleau

Double excitations are crucial to understanding numerous chemical, physical, and biological processes, but accurately predicting them remains a challenge. In this work, we explore the particle-particle random phase approximation (ppRPA) as…

Chemical Physics · Physics 2024-11-26 Jincheng Yu , Jiachen Li , Tianyu Zhu , Weitao Yang

The discovery of polymers with targeted properties is challenged by the vast chemical design space and the limited availability of consistent, high-quality data across multiple properties. In this work, an integrated polymer informatics…

Chemical Physics · Physics 2026-03-31 Sobin Alosious , Yuhan Liu , Jiaxin Xu , Gang Liu , Renzheng Zhang , Meng Jiang , Tengfei Luo

``$\Delta$-machine learning" refers to a machine learning approach to bring a property such as a potential energy surface (PES) based on low-level (LL) density functional theory (DFT) energies and gradients to close to a coupled cluster…

Chemical Physics · Physics 2021-05-21 Apurba Nandi , Chen Qu , Paul Houston , Riccardo Conte , Joel M. Bowman

Modeling non-empirical and highly flexible interatomic potential energy surfaces (PES) using machine learning (ML) approaches is becoming popular in molecular and materials research. Training an ML-PES is typically performed in two stages:…

Materials Science · Physics 2021-01-05 Suresh Kondati Natarajan , Miguel A. Caro

To further develop accurate and large-scale simulations of electrochemical interfaces, we propose a unified explicit electric potential framework to simultaneously predict atomic forces and electron density distributions. The framework…

Chemical Physics · Physics 2026-04-14 Jingwen Zhou , Yawen Yu , Xuwei Liu , Chungen Liu

We investigate the potential of numerical algorithms to decipher the kinetic parameters involved in multi-step chemical reactions. To this end we study a dimerization kinetics of protein as a model system. We follow the dimerization…

Biological Physics · Physics 2014-12-24 Srijeeta Talukder , Shrabani Sen , Ralf Metzler , Suman K Banik , Pinaki Chaudhury

Method of random phase product state (RPPS) is proposed to calculate canonical ensemble average of quantum systems described with matrix product states and also with tensor network states in general. The RPPS method is an extension of the…

Strongly Correlated Electrons · Physics 2020-06-26 Toshiaki Iitaka

Free energy profile (FE Profile) is an essential quantity for the estimation of reaction rate and the validation of reaction mechanism. For chemical reactions in condensed phase or enzymatic reactions, the computation of FE profile at ab…

Computational Physics · Physics 2018-11-15 Pengfei Li , Xiangyu Jia , Xiaoliang Pan , Yihan Shao , Ye Mei

Full dimensional potential energy surfaces (PESs) based on machine learning (ML) techniques provide means for accurate and efficient molecular simulations in the gas- and condensed-phase for various experimental observables ranging from…

Chemical Physics · Physics 2023-07-26 Kaisheng Song , Silvan Käser , Kai Töpfer , Luis Itza Vazquez-Salazar , Markus Meuwly

Free energies are fundamental quantities governing phase behavior and thermodynamic stability in polymer systems, yet their accurate computation often requires extensive simulations and post-processing techniques such as the Bennett…

Soft Condensed Matter · Physics 2026-03-19 Ian Chen , Alfredo Alexander-Katz

This paper introduces a new platform to accelerate the modeling of complex aerothermochemical interactions in new turbomachines, turbo-reactors, to decarbonise chemical processes. While previous work has aerothermally demonstrated the…

Computational Engineering, Finance, and Science · Computer Science 2025-02-13 Dylan Rubini , Budimir Rosic

We propose a nonperturbative scheme for the calculation of thermal damping-rates using exact renormalization group (RG)-equations. Special emphasis is put on the thermal RG where first results for the rate were given in M. Pietroni, Phys.…

High Energy Physics - Phenomenology · Physics 2009-10-31 Bastian Bergerhoff , Juergen Reingruber

We explore the performance of a statistical learning technique based on Gaussian Process (GP) regression as an efficient non-parametric method for constructing multi-dimensional potential energy surfaces (PES) for polyatomic molecules.…

Chemical Physics · Physics 2016-11-23 Jie Cui , Roman V. Krems

Turbulent reacting flows occur in a variety of engineering applications such as chemical reactors and power generating equipment (gas turbines and internal combustion engines). Turbulent reacting flows are characterized by two main…

Computational Engineering, Finance, and Science · Computer Science 2022-10-12 S. M. Aithal

Interactions of polyelectrolytes (PEs) with proteins play a crucial role in numerous biological processes, such as the internalization of virus particles into host cells. Although docking, machine learning methods, and molecular dynamics…

Biomolecules · Quantitative Biology 2024-09-04 Lenard Neander , Cedric Hannemann , Roland R. Netz , Anil Kumar Sahoo

Gaussian process regression has recently emerged as a powerful, system-agnostic tool for building global potential energy surfaces (PES) of polyatomic molecules. While the accuracy of GP models of PES increases with the number of potential…

Chemical Physics · Physics 2019-07-23 Jun Dai , Roman V. Krems
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