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Large-scale quantum devices provide insights beyond the reach of classical simulations. However, for a reliable and verifiable quantum simulation, the building blocks of the quantum device require exquisite benchmarking. This benchmarking…

Quantum Physics · Physics 2022-02-16 Agnes Valenti , Guliuxin Jin , Julian Léonard , Sebastian D. Huber , Eliska Greplova

An energy-based a posteriori error bound is proposed for the physics-informed neural network solutions of elasticity problems. An admissible displacement-stress solution pair is obtained from a mixed form of physics-informed neural…

Numerical Analysis · Mathematics 2022-05-31 Mengwu Guo , Ehsan Haghighat

Computer models, aiming at simulating a complex real system, are often calibrated in the light of data to improve performance. Standard calibration methods assume that the optimal values of calibration parameters are invariant to the model…

Methodology · Statistics 2017-09-01 Georgios Karagiannis , Bledar A. Konomi , Guang Lin

We establish the existence of weak solutions of a nonlinear radiation-type boundary value problem for elliptic equation on divergence form with discontinuous leading coefficient. Quantitative estimates play a crucial role on the real…

Analysis of PDEs · Mathematics 2015-07-23 Luisa Consiglieri

Simulation offers a simple and flexible way to estimate the power of a clinical trial when analytic formulae are not available. The computational burden of using simulation has, however, restricted its application to only the simplest of…

This article presents an error analysis of the symmetric linear/bilinear partially penalized immersed finite element (PPIFE) methods for interface problems of Helmholtz equations. Under the assumption that the exact solution possesses a…

Numerical Analysis · Mathematics 2020-06-22 Ruchi Guo , Tao Lin , Yanping Lin , Qiao Zhuang

The Poisson-Boltzmann equation (PBE) models the electrostatic interactions of charged bodies such as molecules and proteins in an electrolyte solvent. The PBE is a challenging equation to solve numerically due to the presence of…

Numerical Analysis · Mathematics 2018-07-17 Jehanzeb H. Chaudhry

Estimating the ground-state energy of Hamiltonians is a fundamental task for which it is believed that quantum computers can be helpful. Several approaches have been proposed toward this goal, including algorithms based on quantum phase…

Quantum Physics · Physics 2025-11-26 Dhrumil Patel , Daniel Koch , Saahil Patel , Mark M. Wilde

In this perspective, we discuss where and how accounting for electronic many-body polarization affects the accuracy of classical molecular dynamics simulations of biomolecules.While the effects of electronic polarization are highly…

Chemical Physics · Physics 2021-03-29 Josef Melcr , Jean-Philip Piquemal

In this paper we study computationally feasible bounds for relative free energies between two many-particle systems. Specifically, we consider systems out of equilibrium that do not necessarily satisfy a fluctuation-dissipation relation,…

Statistical Mechanics · Physics 2024-03-19 Luigi Delle Site , Carsten Hartmann

We consider a singularly perturbed semilinear boundary value problem of a general form that allows various types of turning points. A solution decomposition is derived that separates the potential exponential boundary layer terms. The…

Numerical Analysis · Mathematics 2017-01-24 Simon Becher

Combining analytical and numerical methods, we study within the framework of the homogeneous non-linear Boltzmann equation, a broad class of models relevant for the dynamics of dissipative fluids, including granular gases. We use the new…

Statistical Mechanics · Physics 2007-09-23 E. Trizac , A. Barrat , M. H. Ernst

The aim of this article is to propose a new reduced-order modelling approach for parametric eigenvalue problems arising in electronic structure calculations. Namely, we develop nonlinear reduced basis techniques for the approximation of…

Numerical Analysis · Mathematics 2025-11-19 Maxime Dalery , Genevieve Dusson , Virginie Ehrlacher , Alexei Lozinski

Almost all fields of science rely upon statistical inference to estimate unknown parameters in theoretical and computational models. While the performance of modern computer hardware continues to grow, the computational requirements for the…

Computation · Statistics 2022-10-25 David J. Warne , Ruth E. Baker , Matthew J. Simpson

Poisson-Boltzmann (PB) theory is the classic approach to soft matter electrostatics which has been applied to numerous problems of physical chemistry and biophysics. Its essential limitations are the neglect of correlation effects and of…

Soft Condensed Matter · Physics 2016-08-03 Sahin Buyukdagli , Ralf Blossey

We consider the Poisson-Boltzmann equation in a periodic cell, representative of a porous medium. It is a model for the electrostatic distribution of $N$ chemical species diluted in a liquid at rest, occupying the pore space with charged…

Analysis of PDEs · Mathematics 2015-04-24 Gregoire Allaire , Jean-Francois Dufreche , Andro Mikelic , Andrey Piatnitski

Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not in general applicable to soft, chemically inhomogeneous systems. The…

Quantum Physics · Physics 2010-07-13 Sarah Harris , Vivien M. Kendon

This work is aimed at the derivation of reliable and efficient a posteriori error estimates for convection-dominated diffusion problems motivated by a linear Fokker-Planck problem appearing in computational neuroscience. We obtain…

Numerical Analysis · Computer Science 2018-05-16 Svetlana Matculevich , Monika Wolfmayr

While most work on the quantum simulation of chemistry has focused on computing energy surfaces, a similarly important application requiring subtly different algorithms is the computation of energy derivatives. Almost all molecular…

The accurate computation of the electrostatic capacity of three dimensional objects is a fascinating benchmark problem with a long and rich history. In particular, the capacity of the unit cube has widely been studied, and recent advances…

Numerical Analysis · Mathematics 2019-10-08 Timo Betcke , Alexander Haberl , Dirk Praetorius