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Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Image segmentation is crucial in many computational pathology pipelines, including accurate disease diagnosis, subtyping, outcome, and survivability prediction. The common approach for training a segmentation model relies on a pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Sachin Kumar Danisetty , Alexandros Graikos , Srikar Yellapragada , Dimitris Samaras

Medical image segmentation is routinely performed to isolate regions of interest, such as organs and lesions. Currently, deep learning is the state of the art for automatic segmentation, but is usually limited by the need for supervised…

Image and Video Processing · Electrical Eng. & Systems 2021-02-05 Umaseh Sivanesan , Luis H. Braga , Ranil R. Sonnadara , Kiret Dhindsa

Pathological structures in medical images are typically deviations from the expected anatomy of a patient. While clinicians consider this interplay between anatomy and pathology, recent deep learning algorithms specialize in recognizing…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Alexander Jaus , Constantin Seibold , Simon Reiß , Lukas Heine , Anton Schily , Moon Kim , Fin Hendrik Bahnsen , Ken Herrmann , Rainer Stiefelhagen , Jens Kleesiek

Semantic medical image segmentation using deep learning has recently achieved high accuracy, making it appealing to clinical problems such as radiation therapy. However, the lack of high-quality semantically labelled data remains a…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Wei Dai , Siyu Liu , Craig B. Engstrom , Shekhar S. Chandra

This paper addresses the problem of pathological lung segmentation, a significant challenge in medical image analysis, particularly pronounced in cases of peripheral opacities (severe fibrosis and consolidation) because of the textural…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Rezkellah Noureddine Khiati , Pierre-Yves Brillet , Aurélien Justet , Radu Ispas , Catalin Fetita

This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Sishuo Liu , Yizhou Yu , Guanbin Li

Image segmentation, the process of partitioning an image into meaningful regions, plays a pivotal role in computer vision and medical imaging applications. Unsupervised segmentation, particularly in the absence of labeled data, remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Kovvuri Sai Gopal Reddy , Bodduluri Saran , A. Mudit Adityaja , Saurabh J. Shigwan , Nitin Kumar

Segmentation of anatomical structures and pathologies is inherently ambiguous. For instance, structure borders may not be clearly visible or different experts may have different styles of annotating. The majority of current state-of-the-art…

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Medical image processing usually requires a model trained with carefully crafted datasets due to unique image characteristics and domain-specific challenges, especially in pathology. Primitive detection and segmentation in digitized tissue…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Abu Bakor Hayat Arnob , Xiangxue Wang , Yiping Jiao , Xiao Gan , Wenlong Ming , Jun Xu

Medical Image Segmentation is a useful application for medical image analysis including detecting diseases and abnormalities in imaging modalities such as MRI, CT etc. Deep learning has proven to be promising for this task but usually has a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Soham Bhosale , Arjun Krishna , Ge Wang , Klaus Mueller

Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Zhiling Yan , Sicheng Chen , Tianyi Zhang , Nan Ying , Yanli Lei , Guanglei Zhang

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Image segmentation is a central topic in image processing and computer vision and a key issue in many applications, e.g., in medical imaging, microscopy, document analysis and remote sensing. According to the human perception, image…

Numerical Analysis · Mathematics 2022-06-24 Laura Antonelli , Valentina De Simone , Daniela di Serafino

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

Accurate detection of all pathological findings in 3D medical images remains a significant challenge, as supervised models are limited to detecting only the few pathology classes annotated in existing datasets. To address this, we frame…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Mikhail Goncharov , Eugenia Soboleva , Mariia Donskova , Daniil Ignatyev , Mikhail Belyaev , Ivan Oseledets , Marina Munkhoeva , Maxim Panov

Accurate medical image segmentation is essential for effective diagnosis and treatment planning but is often challenged by domain shifts caused by variations in imaging devices, acquisition conditions, and patient-specific attributes.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Jie Bao , Zhixin Zhou , Wen Jung Li , Rui Luo

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Ali Hatamizadeh
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