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Linguistic structures exhibit a rich array of global phenomena, however commonly used Markov models are unable to adequately describe these phenomena due to their strong locality assumptions. We propose a novel hierarchical model for…

Machine Learning · Computer Science 2015-03-10 Ehsan Shareghi , Gholamreza Haffari , Trevor Cohn , Ann Nicholson

Nous pr\'esentons dans cette contribution une approche \`a la fois symbolique et probabiliste permettant d'extraire l'information sur la segmentation du signal de parole \`a partir d'information prosodique. Nous utilisons pour ce faire des…

Machine Learning · Computer Science 2008-12-18 Irina Nesterenko , Stéphane Rauzy

Latent tree learning models learn to parse a sentence without syntactic supervision, and use that parse to build the sentence representation. Existing work on such models has shown that, while they perform well on tasks like sentence…

Computation and Language · Computer Science 2018-04-18 Nikita Nangia , Samuel R. Bowman

Proteins populate a manifold in the high-dimensional sequence space whose geometrical structure guides their natural evolution. Leveraging recently-developed structure prediction tools based on transformer models, we first examine the…

Biomolecules · Quantitative Biology 2023-11-13 A. Zambon , R. Zecchina , G. Tiana

Protein representation learning has primarily benefited from the remarkable development of language models (LMs). Accordingly, pre-trained protein models also suffer from a problem in LMs: a lack of factual knowledge. The recent solution…

Machine Learning · Computer Science 2023-02-16 Hong-Yu Zhou , Yunxiang Fu , Zhicheng Zhang , Cheng Bian , Yizhou Yu

Prediction of ligand binding sites of proteins is a fundamental and important task for understanding the function of proteins and screening potential drugs. Most existing methods require experimentally determined protein holo-structures as…

Quantitative Methods · Quantitative Biology 2023-12-07 Shuo Zhang , Lei Xie

Protein-Protein Interactions (PPIs) are fundamental in various biological processes and play a key role in life activities. The growing demand and cost of experimental PPI assays require computational methods for efficient PPI prediction.…

Machine Learning · Computer Science 2024-02-23 Lirong Wu , Yijun Tian , Yufei Huang , Siyuan Li , Haitao Lin , Nitesh V Chawla , Stan Z. Li

Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Recently, due to their capacity and representation ability, pre-trained protein language models have achieved state-of-the-art performance in…

Biomolecules · Quantitative Biology 2024-02-06 Ziyi Zhou , Liang Zhang , Yuanxi Yu , Mingchen Li , Liang Hong , Pan Tan

Recognizing shallow linguistic patterns, such as basic syntactic relationships between words, is a common task in applied natural language and text processing. The common practice for approaching this task is by tedious manual definition of…

cmp-lg · Computer Science 2007-05-23 Shlomo Argamon , Ido Dagan , Yuval Krymolowski

Protein-Protein Interactions (PPIs) perform essential roles in biological functions. Although some experimental techniques have been developed to detect PPIs, they suffer from high false positive and high false negative rates. Consequently,…

Quantitative Methods · Quantitative Biology 2017-12-29 Samaneh Aghajanbaglo , Sobhan Moosavi , Maseud Rahgozar , Amir Rahimi

Common language models typically predict the next word given the context. In this work, we propose a method that improves language modeling by learning to align the given context and the following phrase. The model does not require any…

Computation and Language · Computer Science 2019-06-06 Hongyin Luo , Lan Jiang , Yonatan Belinkov , James Glass

Naturally-occurring bracketings, such as answer fragments to natural language questions and hyperlinks on webpages, can reflect human syntactic intuition regarding phrasal boundaries. Their availability and approximate correspondence to…

Computation and Language · Computer Science 2021-04-30 Tianze Shi , Ozan İrsoy , Igor Malioutov , Lillian Lee

In this paper we consider the problem of context-free grammars comparison from the analysis point of view. We show that the problem can be reduced to numerical solution of systems of nonlinear matrix equations. The approach presented here…

Formal Languages and Automata Theory · Computer Science 2018-04-23 J. Joao Almeida , Eliana Grande , Georgi Smirnov

In this thesis, we present two approaches to a rigorous mathematical and algorithmic foundation of quantitative and statistical inference in constraint-based natural language processing. The first approach, called quantitative constraint…

Computation and Language · Computer Science 2007-05-23 Stefan Riezler

Context-dependent nature of biological phenomena are well documented in every branch of biology. While there have been few previous attempts to (implicitly) model various facets of biological context-dependence, a formal and general…

Other Quantitative Biology · Quantitative Biology 2011-11-28 Anirban Banerji

Tokenization is a crucial step in processing protein sequences for machine learning models, as proteins are complex sequences of amino acids that require meaningful segmentation to capture their functional and structural properties.…

Computation and Language · Computer Science 2024-11-27 Burak Suyunu , Enes Taylan , Arzucan Özgür

Pre-trained language models have demonstrated impressive performance in both natural language processing and program understanding, which represent the input as a token sequence without explicitly modeling its structure. Some prior works…

Computation and Language · Computer Science 2022-10-27 Da Shen , Xinyun Chen , Chenguang Wang , Koushik Sen , Dawn Song

Recent developments in Natural Language Processing (NLP) demonstrate that large-scale, self-supervised pre-training can be extremely beneficial for downstream tasks. These ideas have been adapted to other domains, including the analysis of…

Computation and Language · Computer Science 2021-02-02 Matthew B. A. McDermott , Brendan Yap , Harry Hsu , Di Jin , Peter Szolovits

The analysis of the three-dimensional structure of proteins is an important topic in molecular biochemistry. Structure plays a critical role in defining the function of proteins and is more strongly conserved than amino acid sequence over…

Applications · Statistics 2015-01-19 Abel Rodriguez , Scott C. Schmidler

Recent work on the problem of latent tree learning has made it possible to train neural networks that learn to both parse a sentence and use the resulting parse to interpret the sentence, all without exposure to ground-truth parse trees at…

Computation and Language · Computer Science 2018-02-27 Adina Williams , Andrew Drozdov , Samuel R. Bowman
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