Related papers: Estimating probabilistic context-free grammars for…
Linguistic structures exhibit a rich array of global phenomena, however commonly used Markov models are unable to adequately describe these phenomena due to their strong locality assumptions. We propose a novel hierarchical model for…
Nous pr\'esentons dans cette contribution une approche \`a la fois symbolique et probabiliste permettant d'extraire l'information sur la segmentation du signal de parole \`a partir d'information prosodique. Nous utilisons pour ce faire des…
Latent tree learning models learn to parse a sentence without syntactic supervision, and use that parse to build the sentence representation. Existing work on such models has shown that, while they perform well on tasks like sentence…
Proteins populate a manifold in the high-dimensional sequence space whose geometrical structure guides their natural evolution. Leveraging recently-developed structure prediction tools based on transformer models, we first examine the…
Protein representation learning has primarily benefited from the remarkable development of language models (LMs). Accordingly, pre-trained protein models also suffer from a problem in LMs: a lack of factual knowledge. The recent solution…
Prediction of ligand binding sites of proteins is a fundamental and important task for understanding the function of proteins and screening potential drugs. Most existing methods require experimentally determined protein holo-structures as…
Protein-Protein Interactions (PPIs) are fundamental in various biological processes and play a key role in life activities. The growing demand and cost of experimental PPI assays require computational methods for efficient PPI prediction.…
Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Recently, due to their capacity and representation ability, pre-trained protein language models have achieved state-of-the-art performance in…
Recognizing shallow linguistic patterns, such as basic syntactic relationships between words, is a common task in applied natural language and text processing. The common practice for approaching this task is by tedious manual definition of…
Protein-Protein Interactions (PPIs) perform essential roles in biological functions. Although some experimental techniques have been developed to detect PPIs, they suffer from high false positive and high false negative rates. Consequently,…
Common language models typically predict the next word given the context. In this work, we propose a method that improves language modeling by learning to align the given context and the following phrase. The model does not require any…
Naturally-occurring bracketings, such as answer fragments to natural language questions and hyperlinks on webpages, can reflect human syntactic intuition regarding phrasal boundaries. Their availability and approximate correspondence to…
In this paper we consider the problem of context-free grammars comparison from the analysis point of view. We show that the problem can be reduced to numerical solution of systems of nonlinear matrix equations. The approach presented here…
In this thesis, we present two approaches to a rigorous mathematical and algorithmic foundation of quantitative and statistical inference in constraint-based natural language processing. The first approach, called quantitative constraint…
Context-dependent nature of biological phenomena are well documented in every branch of biology. While there have been few previous attempts to (implicitly) model various facets of biological context-dependence, a formal and general…
Tokenization is a crucial step in processing protein sequences for machine learning models, as proteins are complex sequences of amino acids that require meaningful segmentation to capture their functional and structural properties.…
Pre-trained language models have demonstrated impressive performance in both natural language processing and program understanding, which represent the input as a token sequence without explicitly modeling its structure. Some prior works…
Recent developments in Natural Language Processing (NLP) demonstrate that large-scale, self-supervised pre-training can be extremely beneficial for downstream tasks. These ideas have been adapted to other domains, including the analysis of…
The analysis of the three-dimensional structure of proteins is an important topic in molecular biochemistry. Structure plays a critical role in defining the function of proteins and is more strongly conserved than amino acid sequence over…
Recent work on the problem of latent tree learning has made it possible to train neural networks that learn to both parse a sentence and use the resulting parse to interpret the sentence, all without exposure to ground-truth parse trees at…