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The aim of this paper is to provide a comprehensive review of statistical challenges in neuroimaging data analysis from neuroimaging techniques to large-scale neuroimaging studies to statistical learning methods. We briefly review eight…

Applications · Statistics 2022-10-18 Hongtu Zhu , Tengfei Li , Bingxin Zhao

Gaussian graphical model is a graphical representation of the dependence structure for a Gaussian random vector. It is recognized as a powerful tool in different applied fields such as bioinformatics, error-control codes, speech language,…

Machine Learning · Statistics 2017-01-10 Valery A. Kalyagin , Alexander P. Koldanov , Petr A. Koldanov , Panos M. Pardalos

Turning rich neuroimaging data into mechanistic insight remains challenging. Statistical models capture associations but remain largely agnostic to underlying mechanisms. Biophysical models embody candidate mechanisms but remain difficult…

Neurons and Cognition · Quantitative Biology 2026-01-15 Dominic Boutet , Sylvain Baillet

This article compares ten recently proposed neural networks and proposes two ensemble neural network-based models for blood glucose prediction. All of them are tested under the same dataset, preprocessing workflow, and tools using the…

Quantitative Methods · Quantitative Biology 2021-09-07 Felix Tena , Oscar Garnica , Juan Lanchares , J. Ignacio Hidalgo

While the study of a single network is well-established, technological advances now allow for the collection of multiple networks with relative ease. Increasingly, anywhere from several to thousands of networks can be created from brain…

Applications · Statistics 2021-01-14 Nathaniel Josephs , Lizhen Lin , Steven Rosenberg , Eric D. Kolaczyk

We present an inference method utilizing artificial neural networks for parameter estimation of a quantum probe monitored through a single continuous measurement. Unlike existing approaches focusing on the diffusive signals generated by…

Bayesian Neural Networks (BNNs) offer a principled and natural framework for proper uncertainty quantification in the context of deep learning. They address the typical challenges associated with conventional deep learning methods, such as…

Computation · Statistics 2024-11-13 Zahra Moslemi , Yang Meng , Shiwei Lan , Babak Shahbaba

We present a didactic introduction to spectral Dynamic Causal Modelling (DCM), a Bayesian state-space modelling approach used to infer effective connectivity from non-invasive neuroimaging data. Spectral DCM is currently the most widely…

Neurons and Cognition · Quantitative Biology 2023-09-07 Leonardo Novelli , Karl Friston , Adeel Razi

When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated…

Machine Learning · Computer Science 2013-02-21 George H. John , Pat Langley

Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield unfaithful estimates in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 J. Senapati , A. Guha Roy , S. Pölsterl , D. Gutmann , S. Gatidis , C. Schlett , A. Peters , F. Bamberg , C. Wachinger

In this paper, we revisit the parameter learning problem, namely the estimation of model parameters for Dynamic Bayesian Networks (DBNs). DBNs are directed graphical models of stochastic processes that encompasses and generalize Hidden…

Machine Learning · Computer Science 2019-02-14 E. Benhamou , J. Atif , R. Laraki

Neuroscience has recently made much progress, expanding the complexity of both neural-activity measurements and brain-computational models. However, we lack robust methods for connecting theory and experiment by evaluating our new big…

Quantitative Methods · Quantitative Biology 2023-07-06 Heiko H. Schütt , Alexander D. Kipnis , Jörn Diedrichsen , Nikolaus Kriegeskorte

Differential networks (DN) are important tools for modeling the changes in conditional dependencies between multiple samples. A Bayesian approach for estimating DNs, from the classical viewpoint, is introduced with a computationally…

Methodology · Statistics 2022-04-06 Jarod Smith , Mohammad Arashi , Andriette Bekker

Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

Quantitative Methods · Quantitative Biology 2019-09-27 Po-Ya Hsu

The desire to train complex machine learning algorithms and to increase the statistical power in association studies drives neuroimaging research to use ever-larger datasets. The most obvious way to increase sample size is by pooling scans…

Computer Vision and Pattern Recognition · Computer Science 2020-10-29 Christian Wachinger , Anna Rieckmann , Sebastian Pölsterl

Understanding real-world dynamical phenomena remains a challenging task. Across various scientific disciplines, machine learning has advanced as the go-to technology to analyze nonlinear dynamical systems, identify patterns in big data, and…

Machine Learning · Computer Science 2022-12-07 Kevin Linka , Amelie Schafer , Xuhui Meng , Zongren Zou , George Em Karniadakis , Ellen Kuhl

Screening mammograms is the gold standard for detecting breast cancer early. While a good amount of work has been performed on mammography image classification, especially with deep neural networks, there has not been much exploration into…

Machine Learning · Computer Science 2020-08-14 Anika Tabassum , Naimul Khan

There are many issues that can cause problems when attempting to infer model parameters from data. Data and models are both imperfect, and as such there are multiple scenarios in which standard methods of inference will lead to misleading…

Computation · Statistics 2024-05-01 Simon L. Cotter

Deep neural networks (DNN) are versatile parametric models utilised successfully in a diverse number of tasks and domains. However, they have limitations---particularly from their lack of robustness and over-sensitivity to out of…

Machine Learning · Statistics 2020-01-01 John Mitros , Brian Mac Namee

Parameter ensembles or sets of random effects constitute one of the cornerstones of modern statistical practice. This is especially the case in Bayesian hierarchical models, where several decision theoretic frameworks can be deployed. The…

Statistics Theory · Mathematics 2015-03-19 Cedric E. Ginestet