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Genomic studies face a vast hypothesis space, while interventions such as gene perturbations remain costly and time-consuming. To accelerate such experiments, gene perturbation models predict the transcriptional outcome of interventions.…

Quantitative Methods · Quantitative Biology 2025-10-21 George Panagopoulos , Johannes F. Lutzeyer , Sofiane Ennadir , Michalis Vazirgiannis , Jun Pang

For autonomous agents to successfully operate in real world, the ability to anticipate future motions of surrounding entities in the scene can greatly enhance their safety levels since potentially dangerous situations could be avoided in…

Machine Learning · Computer Science 2019-06-04 Yeping Hu , Wei Zhan , Liting Sun , Masayoshi Tomizuka

Designing composite materials as per the application requirements is fundamentally a challenging and time consuming task. Here we report the development of a deep neural network based computational framework capable of solving the forward…

Materials Science · Physics 2022-09-14 Ashank , Soumen Chakravarty , Pranshu Garg , Ankit Kumar , Manish Agrawal , Prabhat K. Agnihotri

Human motion is stochastic and ensuring safe robot navigation in a pedestrian-rich environment requires proactive decision-making. Past research relied on incorporating deterministic future states of surrounding pedestrians which can be…

Robotics · Computer Science 2025-02-18 Anshul Nayak , Azim Eskandarian

Mathematical modeling is an essential step, for example, to analyze the transient behavior of a dynamical process and to perform engineering studies such as optimization and control. With the help of first-principles and expert knowledge, a…

Machine Learning · Computer Science 2021-03-30 Pawan Goyal , Peter Benner

In order to plan a safe maneuver an autonomous vehicle must accurately perceive its environment, and understand the interactions among traffic participants. In this paper, we aim to learn scene-consistent motion forecasts of complex urban…

Computer Vision and Pattern Recognition · Computer Science 2020-07-24 Sergio Casas , Cole Gulino , Simon Suo , Katie Luo , Renjie Liao , Raquel Urtasun

We revisit the problem of motion planning in the Gaussian belief space. Motivated by the fact that most existing sampling-based planners suffer from high computational costs due to the high-dimensional nature of the problem, we propose an…

Robotics · Computer Science 2024-09-20 Lukas Taus , Vrushabh Zinage , Takashi Tanaka , Richard Tsai

Latent force models are a class of hybrid models for dynamic systems, combining simple mechanistic models with flexible Gaussian process (GP) perturbations. An extension of this framework to include multiplicative interactions between the…

Machine Learning · Statistics 2019-01-01 Daniel J. Tait , Bruce J. Worton

In the past few years, machine learning-based approaches have had some great success for rendering animated feature films. This survey summarizes several of the most dramatic improvements in using deep neural networks over traditional…

Graphics · Computer Science 2020-05-27 Shilin Zhu

High-level driving behavior decision-making is an open-challenging problem for connected vehicle technology, especially in heterogeneous traffic scenarios. In this paper, a deep reinforcement learning based high-level driving behavior…

Machine Learning · Computer Science 2019-02-27 Zhengwei Bai , Baigen Cai , Wei Shangguan , Linguo Chai

We present a deep transformation model for probabilistic regression. Deep learning is known for outstandingly accurate predictions on complex data but in regression tasks, it is predominantly used to just predict a single number. This…

Machine Learning · Statistics 2020-04-02 Beate Sick , Torsten Hothorn , Oliver Dürr

A large part of the interest in model-based reinforcement learning derives from the potential utility to acquire a forward model capable of strategic long term decision making. Assuming that an agent succeeds in learning a useful predictive…

Machine Learning · Computer Science 2021-06-29 Alvaro Ovalle , Simon M. Lucas

This work presents a methodology for modeling and predicting human behavior in settings with N humans interacting in highly multimodal scenarios (i.e. where there are many possible highly-distinct futures). A motivating example includes…

Robotics · Computer Science 2018-07-27 Boris Ivanovic , Edward Schmerling , Karen Leung , Marco Pavone

Dexterous multi-fingered hands can provide robots with the ability to flexibly perform a wide range of manipulation skills. However, many of the more complex behaviors are also notoriously difficult to control: Performing in-hand object…

Robotics · Computer Science 2019-09-26 Anusha Nagabandi , Kurt Konoglie , Sergey Levine , Vikash Kumar

Recent advances in generative models have yielded impressive progress on motion in-betweening, allowing for more complex, varied, and realistic motion transitions. However, recent methods still exhibit noticeable limitations in preserving…

Graphics · Computer Science 2026-05-14 Shiyu Fan , Paul Henderson , Edmond S. L. Ho

This study develops a robot mobility policy based on deep reinforcement learning. Since traditional methods of conventional robotic navigation depend on accurate map reproduction as well as require high-end sensors, learning-based methods…

Robotics · Computer Science 2020-12-22 Minh Q. Tran , Ngoc Q. Ly

Robots that can execute various tasks automatically on behalf of humans are becoming an increasingly important focus of research in the field of robotics. Imitation learning has been studied as an efficient and high-performance method, and…

Robotics · Computer Science 2021-02-05 Ayumu Sasagawa , Sho Sakaino , Toshiaki Tsuji

We present a navigation system that combines ideas from hierarchical planning and machine learning. The system uses a traditional global planner to compute optimal paths towards a goal, and a deep local trajectory planner and velocity…

Motion generation, the task of synthesizing realistic motion sequences from various conditioning inputs, has become a central problem in computer vision, computer graphics, and robotics, with applications ranging from animation and virtual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Aliasghar Khani , Arianna Rampini , Bruno Roy , Larasika Nadela , Noa Kaplan , Evan Atherton , Derek Cheung , Jacky Bibliowicz

A fundamental computation for statistical inference and accurate decision-making is to compute the marginal probabilities or most probable states of task-relevant variables. Probabilistic graphical models can efficiently represent the…

Machine Learning · Computer Science 2019-06-28 KiJung Yoon , Renjie Liao , Yuwen Xiong , Lisa Zhang , Ethan Fetaya , Raquel Urtasun , Richard Zemel , Xaq Pitkow
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