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Ab initio Born-Oppenheimer molecular dynamics (AIMD) is a valuable method for simulating physico-chemical processes of complex systems, including reactive systems, and for training machine learning models and force fields. Speed and…

This paper presents a heterogeneous adaptive mesh refinement (AMR) framework for efficient simulation of moderately stiff reactive problems. This framework features an elaborate subcycling-in-time algorithm along with a specialized…

Computational Physics · Physics 2025-06-04 Yuqi Wang , Yadong Zeng , Ralf Deiterding , Jianhan Liang

We introduce JAX MD, a software package for performing differentiable physics simulations with a focus on molecular dynamics. JAX MD includes a number of physics simulation environments, as well as interaction potentials and neural networks…

Computational Physics · Physics 2020-12-04 Samuel S. Schoenholz , Ekin D. Cubuk

This study explores the use of INT8-based emulation for accelerating traditional FP64-based HPC workloads on modern GPU architectures. Through SCILIB-Accel automatic BLAS offload tool for cache-coherent Unified Memory Architecture, we…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-01 Hang Liu , Junjie Li , Yinzhi Wang , Niraj K. Nepal , Yang Wang

This paper focuses on the problem of supplying the workstations of assembly lines with components during the production process. For that specific problem, this paper presents a Mixed Integer Linear Program (MILP) that aims at minimizing…

We introduce a novel simple algorithm for thermostatting path integral molecular dynamics (PIMD) with the Langevin equation. The staging transformation of path integral beads is employed for demonstration. The optimum friction coefficients…

Statistical Mechanics · Physics 2017-10-17 Jian Liu , Dezhang Li , Xinzijian Liu

Molecular Dynamics (MD) simulations are essential for understanding the atomic-level behavior of molecular systems, giving insights into their transitions and interactions. However, classical MD techniques are limited by the trade-off…

Biomolecules · Quantitative Biology 2026-04-21 Ziyang Yu , Wenbing Huang , Yang Liu

Robot learning requires adaptation methods that improve reliably from limited, mixed-quality interaction data. This is especially challenging in long-horizon, contact-rich tasks, where end-to-end policy finetuning remains inefficient and…

Mixed Integer Linear Programming (MILP) is a fundamental tool for modeling combinatorial optimization problems. Recently, a growing body of research has used machine learning to accelerate MILP solving. Despite the increasing popularity of…

Machine Learning · Computer Science 2024-10-29 Weimin Huang , Taoan Huang , Aaron M Ferber , Bistra Dilkina

A free data-analysis framework for muSR has been developed. musrfit is fully written in C++, is running under GNU/Linux, Mac OS X, as well as Microsoft Windows, and is distributed under the terms of the GNU GPL. It is based on the CERN ROOT…

Data Analysis, Statistics and Probability · Physics 2012-12-21 A. Suter , B. M. Wojek

Molecular simulation is a scientific tool dealing with challenges in material science and biology. This is reflected in a permanent development and enhancement of algorithms within scientific simulation packages. Here, we present…

Processing-In-Memory (PIM) is a novel approach that augments existing DRAM memory chips with lightweight logic. By allowing to offload computations to the PIM system, this architecture allows for circumventing the data-bottleneck problem…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-18 André Lopes , Daniel Castro , Paolo Romano

Machine learning interatomic potentials (MLIPs) are changing atomistic simulations in the field of chemistry and materials science. However, constructing a single universal MLIP that can accurately model molecular and crystalline systems…

Chemical Physics · Physics 2025-11-11 Tomoya Shiota , Kenji Ishihara , Tuan Minh Do , Toshio Mori , Wataru Mizukami

This paper invites the reader to experiment with an easy-to-use MATLAB implementation of Metropolis integrators for Molecular Dynamics (MD) simulation. These integrators are analysis-based, in the sense that they can rigorously simulate…

Computational Physics · Physics 2013-09-20 Nawaf Bou-Rabee

Foundation models achieve state-of-the-art performance across different tasks, but their size and computational demands raise concerns about accessibility and sustainability. Existing efficiency methods often require additional retraining…

This paper discusses our proposal and implementation of Distill, a domain-specific compilation tool based on LLVM to accelerate cognitive models. Cognitive models explain the process of cognitive function and offer a path to human-like…

Programming Languages · Computer Science 2022-01-17 Jan Vesely , Raghavendra Pradyumna Pothukuchi , Ketaki Joshi , Samyak Gupta , Jonathan D. Cohen , Abhishek Bhattacharjee

The AMIDST Toolbox is a software for scalable probabilistic machine learning with a spe- cial focus on (massive) streaming data. The toolbox supports a flexible modeling language based on probabilistic graphical models with latent variables…

Transformer-based models, such as BERT and ViT, have achieved state-of-the-art results across different natural language processing (NLP) and computer vision (CV) tasks. However, these models are extremely memory intensive during their…

Computation and Language · Computer Science 2023-05-31 Arash Ardakani , Altan Haan , Shangyin Tan , Doru Thom Popovici , Alvin Cheung , Costin Iancu , Koushik Sen

Recently proposed modifications of the standard particle-in-cell (PIC) method resolve long-standing limitations such as exact preservation of physically conserved quantities and unbiased ensemble down-sampling. Such advances pave the way…

Plasma Physics · Physics 2026-03-13 Frida Brogren , Christoffer Olofsson , Joel Magnusson , Arkady Gonoskov

Processing-in-Memory (PIM) enhances memory with computational capabilities, potentially solving energy and latency issues associated with data transfer between memory and processors. However, managing concurrent computation and data flow…

Hardware Architecture · Computer Science 2025-05-09 Ahmed Mamdouh , Haoran Geng , Michael Niemier , Xiaobo Sharon Hu , Dayane Reis
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