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Related papers: TractSeg - Fast and accurate white matter tract se…

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We present a novel dual-encoded magnetization transfer (MT) and diffusion-weighted sequence and demonstrate its potential to resolve distinct properties of white matter fiber tracts at the sub-voxel level. The sequence was designed and…

Streamline classification is essential to identify anatomically meaningful white matter tracts from diffusion MRI (dMRI) tractography. However, current streamline classification methods rely primarily on the geometric features of the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Haotian Yan , Bocheng Guo , Jianzhong He , Nir A. Sochen , Ofer Pasternak , Lauren J O'Donnell , Fan Zhang

Diffusion MRI tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections. White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Tengfei Xue , Fan Zhang , Chaoyi Zhang , Yuqian Chen , Yang Song , Alexandra J. Golby , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Neuroimaging measures of the brain's white matter connections can enable the prediction of non-imaging phenotypes, such as demographic and cognitive measures. Existing works have investigated traditional microstructure and connectivity…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Wan Liu , Yuqian Chen , Chuyang Ye , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Tractograms are virtual representations of the white matter fibers of the brain. They are of primary interest for tasks like presurgical planning, and investigation of neuroplasticity or brain disorders. Each tractogram is composed of…

Neurons and Cognition · Quantitative Biology 2020-07-10 Pietro Astolfi , Ruben Verhagen , Laurent Petit , Emanuele Olivetti , Jonathan Masci , Davide Boscaini , Paolo Avesani

White matter tract microstructure has been shown to influence neuropsychological scores of cognitive performance. However, prediction of these scores from white matter tract data has not been attempted. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-07 Yuqian Chen , Fan Zhang , Chaoyi Zhang , Tengfei Xue , Leo R. Zekelman , Jianzhong He , Yang Song , Nikos Makris , Yogesh Rathi , Alexandra J. Golby , Weidong Cai , Lauren J. O'Donnell

Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs) that describe the distribution, direction, and volume of…

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

The shape of the brain's white matter connections is relatively unexplored in diffusion MRI tractography analysis. While it is known that tract shape varies in populations and across the human lifespan, it is unknown if the variability in…

White matter fiber clustering is an important strategy for white matter parcellation, which enables quantitative analysis of brain connections in health and disease. In combination with expert neuroanatomical labeling, data-driven white…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Yuqian Chen , Chaoyi Zhang , Tengfei Xue , Yang Song , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Our understanding of the human connectome is fundamentally limited by the resolution of diffusion MR images. Reconstructing a connectome's constituent neural pathways with tractography requires following a continuous field of fiber…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Tyler Spears , P. Thomas Fletcher

We present a geometric framework for aligning white matter fiber tracts. By registering fiber tracts between brains, one expects to see overlap of anatomical structures that often provide meaningful comparisons across subjects. However, the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Andrew Lizarraga , David Lee , Antoni Kubicki , Ashish Sahib , Elvis Nunez , Katherine Narr , Shantanu H. Joshi

Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a…

Image and Video Processing · Electrical Eng. & Systems 2019-07-05 Jimit Doshi , Guray Erus , Mohamad Habes , Christos Davatzikos

We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volumes. Further, our method…

Neurons and Cognition · Quantitative Biology 2015-12-24 Demian Wassermann , Makris Nikos , Yogesh Rathi , Shenton Martha , Ron Kikinis , Marek Kubicki , Carl-Fredrik Westin

In this work, we explore the various Brain Neuron tracking techniques, which is one of the most significant applications of Diffusion Tensor Imaging. Tractography provides us with a non-invasive method to analyze underlying tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Nandakishore Puttashamachar , Ulas Bagci

The study of brain differences across Eastern and Western populations provides vital insights for understanding potential cultural and genetic influences on cognition and mental health. Diffusion MRI (dMRI) tractography is an important tool…

White matter fiber clustering (WMFC) enables parcellation of white matter tractography for applications such as disease classification and anatomical tract segmentation. However, the lack of ground truth and the ambiguity of fiber data (the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Yuqian Chen , Chaoyi Zhang , Yang Song , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Yui Lo , Yuqian Chen , Dongnan Liu , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

Purpose: To propose a deep learning-based reconstruction framework for ultrafast and robust diffusion tensor imaging and fiber tractography. Methods: We propose SuperDTI to learn the nonlinear relationship between diffusion-weighted images…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Hongyu Li , Zifei Liang , Chaoyi Zhang , Ruiying Liu , Jing Li , Weihong Zhang , Dong Liang , Bowen Shen , Xiaoliang Zhang , Yulin Ge , Jiangyang Zhang , Leslie Ying

White matter (WM) tract segmentation is a crucial step for brain connectivity studies. It is performed on diffusion magnetic resonance imaging (dMRI), and deep neural networks (DNNs) have achieved promising segmentation accuracy. Existing…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Wan Liu , Chuyang Ye