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Clinical decision support systems are software tools that help clinicians to make medical decisions. However, their acceptance by clinicians is usually rather low. A known problem is that they often require clinicians to manually enter lots…

Artificial Intelligence · Computer Science 2023-09-20 Jean-Baptiste Lamy , Abdelmalek Mouazer , Karima Sedki , Sophie Dubois , Hector Falcoff

Recent efforts in bioinformatics have achieved tremendous progress in the machine reading of biomedical literature, and the assembly of the extracted biochemical interactions into large-scale models such as protein signaling pathways.…

Artificial Intelligence · Computer Science 2017-09-04 Enrique Noriega-Atala , Marco A. Valenzuela-Escarcega , Clayton T. Morrison , Mihai Surdeanu

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates…

Biomedical research yields a wealth of information, much of which is only accessible through the literature. Consequently, literature search is an essential tool for building on prior knowledge in clinical and biomedical research. Although…

Information Retrieval · Computer Science 2024-04-10 Qiao Jin , Robert Leaman , Zhiyong Lu

Information needs are naturally represented as questions. Automatic Natural-Language Question Answering (NLQA) has only recently become a practical task on a larger scale and without domain constraints. This paper gives a brief introduction…

Computation and Language · Computer Science 2007-05-23 Jochen L. Leidner

Medical dialogue systems have attracted significant attention for their potential to act as medical assistants. Enabling these medical systems to emulate clinicians' diagnostic reasoning process has been the long-standing research focus.…

Computation and Language · Computer Science 2024-06-21 Kaishuai Xu , Yi Cheng , Wenjun Hou , Qiaoyu Tan , Wenjie Li

Patient recruitment remains a major bottleneck in clinical trials, calling for scalable and automated solutions. We present TrialMatchAI, an AI-powered recommendation system that automates patient-to-trial matching by processing…

Medical Visual Question Answering (Med-VQA) represents a critical and challenging subtask within the general VQA domain. Despite significant advancements in general VQA, multimodal large language models (MLLMs) still exhibit substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Hongyu Ge , Longkun Hao , Zihui Xu , Zhenxin Lin , Bin Li , Shoujun Zhou , Hongjin Zhao , Yihang Liu

Medical Visual Question Answering (Med-VQA) is a very important task in healthcare industry, which answers a natural language question with a medical image. Existing VQA techniques in information systems can be directly applied to solving…

Artificial Intelligence · Computer Science 2023-12-14 Xiaojie Hong , Zixin Song , Liangzhi Li , Xiaoli Wang , Feiyan Liu

In recent years, interest has arisen in using machine learning to improve the efficiency of automatic medical consultation and enhance patient experience. In this article, we propose two frameworks to support automatic medical consultation,…

Computation and Language · Computer Science 2022-12-27 Wei Chen , Zhiwei Li , Hongyi Fang , Qianyuan Yao , Cheng Zhong , Jianye Hao , Qi Zhang , Xuanjing Huang , Jiajie Peng , Zhongyu Wei

Visual Question Answering (VQA) models aim to answer natural language questions about given images. Due to its ability to ask questions that differ from those used when training the model, medical VQA has received substantial attention in…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Sergio Tascon-Morales , Pablo Márquez-Neila , Raphael Sznitman

Large language models (LLMs) show promise for clinical use. They are often evaluated using datasets such as MedQA. However, Many medical datasets, such as MedQA, rely on simplified Question-Answering (Q\A) that underrepresents real-world…

Computation and Language · Computer Science 2025-10-24 Yunpeng Xiao , Carl Yang , Mark Mai , Xiao Hu , Kai Shu

Health care professionals rely on treatment search engines to efficiently find adequate clinical trials and early access programs for their patients. However, doctors lose trust in the system if its underlying processes are unclear and…

Information Retrieval · Computer Science 2021-10-26 Edeline Contempré , Zoltán Szlávik , Majid Mohammadi , Erick Velazquez , Annette ten Teije , Ilaria Tiddi

Clinicians often need to retrieve patient-specific information from electronic health records (EHRs), a task that is time-consuming and error-prone. We present a locally deployable Clinical Contextual Question Answering (CCQA) framework…

Computation and Language · Computer Science 2026-03-30 Mikko Saukkoriipi , Nicole Hernandez , Jaakko Sahlsten , Kimmo Kaski , Otso Arponen

The medical conversational system can relieve the burden of doctors and improve the efficiency of healthcare, especially during the pandemic. This paper presents a medical conversational question answering (CQA) system based on the…

Computation and Language · Computer Science 2025-03-26 Fei Xia , Bin Li , Yixuan Weng , Shizhu He , Kang Liu , Bin Sun , Shutao Li , Jun Zhao

Question answering over knowledge bases (KBQA) has become a popular approach to help users extract information from knowledge bases. Although several systems exist, choosing one suitable for a particular application scenario is difficult.…

Computation and Language · Computer Science 2022-11-16 Khiem Vinh Tran , Hao Phu Phan , Khang Nguyen Duc Quach , Ngan Luu-Thuy Nguyen , Jun Jo , Thanh Tam Nguyen

Large language models (LLMs) are increasingly used for diagnostic tasks in medicine. In clinical practice, the correct diagnosis can rarely be immediately inferred from the initial patient presentation alone. Rather, reaching a diagnosis…

Artificial Intelligence · Computer Science 2026-02-20 Hui Min Wong , Philip Heesen , Pascal Janetzky , Martin Bendszus , Stefan Feuerriegel

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Large language models (LLMs) hold great promise for assisting clinical interviews due to their fluent interactive capabilities and extensive medical knowledge. However, the lack of high-quality interview dialogue data and widely accepted…

Computation and Language · Computer Science 2025-04-15 Jing Chen , Zhihua Wei , Wei Zhang , Yingying Hu , Qiong Zhang

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu