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We investigate the stimulus-dependent tuning properties of a noisy ionic conductance model for intrinsic subthreshold oscillations in membrane potential and associated spike generation. On depolarization by an applied current, the model…

Neurons and Cognition · Quantitative Biology 2009-11-11 Martin Tobias Huber And Hans Albert Braun

Cellular-level neuron stimulation has attracted much attention in the areas of prevention, diagnosis and treatment of neurological disorders. Herein, we propose a spintronic neurostimulator based on the domain wall movement inside…

Medical Physics · Physics 2020-01-08 Diqing Su , Kai Wu , Renata Saha , Jian-Ping Wang

The current-voltage (I-V) conversion characterizes the physiology of cellular microdomains and reflects cellular communication, excitability, and electrical transduction. Yet deriving such I-V laws remains a major challenge in most cellular…

Neurons and Cognition · Quantitative Biology 2018-08-29 J. Cartailler , D. Holcman

This paper introduces a novel approach in neuromorphic computing, integrating heterogeneous hardware nodes into a unified, massively parallel architecture. Our system transcends traditional single-node constraints, harnessing the neural…

Hardware Architecture · Computer Science 2024-10-02 Murat Isik , Jonathan Naoukin , I. Can Dikmen

Neural systems use the same underlying computational substrate to carry out analog filtering and signal processing operations, as well as discrete symbol manipulation and digital computation. Inspired by the computational principles of…

Neural and Evolutionary Computing · Computer Science 2025-02-28 Dmitrii Zendrikov , Alessio Franci , Giacomo Indiveri

A new stimulation paradigm is presented for the stimulation of nerve cells by extracellular electric currents. In the new paradigm stimulation is achieved with the current spike induced by a voltage step whenever the voltage step is applied…

Other Quantitative Biology · Quantitative Biology 2016-03-08 Erich W. Schmid

We present NeuroMorph, a new neural network architecture that takes as input two 3D shapes and produces in one go, i.e. in a single feed forward pass, a smooth interpolation and point-to-point correspondences between them. The…

Computer Vision and Pattern Recognition · Computer Science 2021-06-18 Marvin Eisenberger , David Novotny , Gael Kerchenbaum , Patrick Labatut , Natalia Neverova , Daniel Cremers , Andrea Vedaldi

We propose a neural information processing system which is obtained by re-purposing the function of a biological neural circuit model, to govern simulated and real-world control tasks. Inspired by the structure of the nervous system of the…

Machine Learning · Computer Science 2019-11-21 Ramin Hasani , Mathias Lechner , Alexander Amini , Daniela Rus , Radu Grosu

The paper proposes the method to analyze the internal dynamics of nanoscopic systems by periodic modulation of the electrochemical potentials of the attached leads and measuring the time-averaged current. The idea is presented using the…

Mesoscale and Nanoscale Physics · Physics 2017-11-15 Krzysztof Ptaszynski

In this study, we present a highly configurable neuromorphic computing substrate and use it for emulating several types of neural networks. At the heart of this system lies a mixed-signal chip, with analog implementations of neurons and…

Neurons in the nervous system are submitted to distinct sources of noise, such as ionic-channel and synaptic noise, which introduces variability in their responses to repeated presentations of identical stimuli. This motivates the use of…

On-chip learning is key to scalable and adaptive neuromorphic systems, yet existing training methods are either difficult to implement in hardware or overly restrictive. However, recent studies show that feedback-control optimizers can…

The problem of maintaining the output of a positive time-invariant single-input single-output system within a predefined corridor of values is treated. For third-order plants possessing a certain structure, it is proven that the problem is…

Systems and Control · Electrical Eng. & Systems 2026-01-21 Alexander Medvedev , Anton V. Proskurnikov

Periodic pulse train stimulation is generically used to study the function of the nervous system and to counteract disease-related neuronal activity, e.g., collective periodic neuronal oscillations. The efficient control of neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-08-05 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

Cryogenic neuromorphic systems, inspired by the brains unparalleled efficiency, present a promising paradigm for next generation computing architectures.This work introduces a fully integrated neuromorphic framework that combines…

Emerging Technologies · Computer Science 2025-01-15 Md Mazharul Islam , Julia Steed , Karan Patel , Catherine Schuman , Ahmedullah Aziz

We study a system of dynamical units, each of which shows excitable or oscillatory behavior, depending on the choice of parameters. When we couple these units with repressive bonds, we can control the duration of collective oscillations for…

Molecular Networks · Quantitative Biology 2014-02-06 Darka Labavic , Hildegard Meyer-Ortmanns

Neuromorphic computing systems comprise networks of neurons that use asynchronous events for both computation and communication. This type of representation offers several advantages in terms of bandwidth and power consumption in…

Hardware Architecture · Computer Science 2017-11-07 Saber Moradi , Ning Qiao , Fabio Stefanini , Giacomo Indiveri

In this article, we study optimal control problems of spiking neurons whose dynamics are described by a phase model. We design minimum-power current stimuli (controls) that lead to targeted spiking times of neurons, where the cases with…

Dynamical Systems · Mathematics 2010-11-18 Isuru Dasanayake , Jr-Shin Li

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

Application of neuromorphic edge devices for control is limited by the constraints on gradient-free online learning and scalability of the hardware across control problems. This paper introduces a synaptic Q-learning algorithm for the…

Systems and Control · Electrical Eng. & Systems 2025-11-21 Shreyan Banerjee , Aasifa Rounak , Vikram Pakrashi
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