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The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…

Neurons and Cognition · Quantitative Biology 2025-01-17 Adam S. Charles

In neural networks literature, there is a strong interest in identifying and defining activation functions which can improve neural network performance. In recent years there has been a renovated interest of the scientific community in…

Machine Learning · Computer Science 2021-03-01 Andrea Apicella , Francesco Donnarumma , Francesco Isgrò , Roberto Prevete

This work introduces a novel training paradigm that draws from affective neuroscience. Inspired by the interplay of emotions and cognition in the human brain and more specifically the SEEKING motivational state, we design a dual-model…

Artificial Intelligence · Computer Science 2026-02-25 Mehdi Acheli , Walid Gaaloul

To understand the biological characteristics of neurological disorders with functional connectivity (FC), recent studies have widely utilized deep learning-based models to identify the disease and conducted post-hoc analyses via explainable…

Machine Learning · Computer Science 2023-10-09 Eunsong Kang , Da-woon Heo , Jiwon Lee , Heung-Il Suk

The regression of a functional response on a set of scalar predictors can be a challenging task, especially if there is a large number of predictors, or the relationship between those predictors and the response is nonlinear. In this work,…

Machine Learning · Statistics 2023-08-24 Sidi Wu , Cédric Beaulac , Jiguo Cao

Brain activity is intrinsically a neural dynamic process constrained by anatomical space. This leads to significant variations in spatial distribution patterns and correlation patterns of neural activity across variable and heterogeneous…

Machine Learning · Computer Science 2026-03-10 Hongjie Jiang , Yifei Tang , Shuqiang Wang

We report measurements of the brain activity of subjects engaged in behavioral exchanges with their environments. We observe brain states which are characterized by coordinated oscillation of populations of neurons that are changing rapidly…

Neurons and Cognition · Quantitative Biology 2007-05-23 Walter J. Freeman , Giuseppe Vitiello

A pervasive research protocol of cognitive neuroscience is to train subjects to perform deliberately designed experiments and record brain activity simultaneously, aiming to understand the brain mechanism underlying cognition. However, how…

Neurons and Cognition · Quantitative Biology 2023-03-13 Zedong Bi

Designing an effective reward function has long been a challenge in reinforcement learning, particularly for complex tasks in unstructured environments. To address this, various learning paradigms have emerged that leverage different forms…

Machine Learning · Computer Science 2025-04-29 Muhammad Qasim Elahi , Somtochukwu Oguchienti , Maheed H. Ahmed , Mahsa Ghasemi

Task based neuroimaging tools for the study of cognitive neuroscience provide insight into understanding how the brain responds to increasing cognitive demand. Theoretical models of neural-cognitive relationships have been developed based…

Quantitative Methods · Quantitative Biology 2016-06-21 Jason Steffener , Karen Li , Syrina Alain , Johannes Frasnelli

Neurofeedback is a non-invasive brain training with long-term medical and non-medical applications. Despite the existence of several emotion regulation studies using neurofeedback, further investigation is needed to understand interactions…

Neurons and Cognition · Quantitative Biology 2020-06-19 Amin Dehghani , Hamid Soltanian-Zadeh , Gholam-Ali Hossein-Zadeh

The interactions play one of the central roles in the brain mediating various processes and functions. They are particularly important for the brain as a complex system that has many different functions from the same structural…

Adaptation and Self-Organizing Systems · Physics 2020-08-19 Tomislav Stankovski

Neural electrical activity is fundamental to brain function, underlying a range of cognitive and behavioral processes, including movement, perception, decision-making, and consciousness. Abnormal patterns of neural signaling often indicate…

Neurons and Cognition · Quantitative Biology 2025-09-03 Zhizhang Yuan , Fanqi Shen , Meng Li , Yuguo Yu , Chenhao Tan , Yang Yang

The bias/variance tradeoff is fundamental to learning: increasing a model's complexity can improve its fit on training data, but potentially worsens performance on future samples. Remarkably, however, the human brain effortlessly handles a…

Neurons and Cognition · Quantitative Biology 2012-10-18 David Balduzzi

Human learning is a complex process in which future behavior is altered via the reorganization of brain activity and connectivity. It remains unknown whether activity and connectivity differentially reorganize during learning, and, if so,…

The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…

Neurons and Cognition · Quantitative Biology 2015-10-28 Richard F. Betzel , Bratislav Mišić , Ye He , Jeffrey Rumschlag , Xi-Nian Zuo , Olaf Sporns

In recent years, the field of neuroscience has gone through rapid experimental advances and a significant increase in the use of quantitative and computational methods. This growth has created a need for clearer analyses of the theory and…

Feedback Alignment (FA) methods are biologically inspired local learning rules for training neural networks with reduced communication between layers. While FA has potential applications in distributed and privacy-aware ML, limitations in…

Machine Learning · Computer Science 2024-06-05 Zachary Robertson , Oluwasanmi Koyejo

Explaining the predictions of neural black-box models is an important problem, especially when such models are used in applications where user trust is crucial. Estimating the influence of training examples on a learned neural model's…

Machine Learning · Computer Science 2020-12-16 Carolin Lawrence , Timo Sztyler , Mathias Niepert

In recent years, neuroscience has made significant progress in building large-scale artificial neural network (ANN) models of brain activity and behavior. However, there is no consensus on the most efficient ways to collect data and design…

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