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Polymer translocation through a nanometer-scale pore assisted by chaperones binding to the polymer is a process encountered in vivo for proteins. Studying the relevant models by computer simulations is computationally demanding.…

Biological Physics · Physics 2017-12-18 P. M. Suhonen , R. P. Linna

Chaperone-assisted biopolymer translocation is the main model proposed for translocation \textit{in vivo}. A dynamical Monte Carlo method is used to simulate the translocation of a stiff homopolymer through a nanopore driven by chaperones.…

Biological Physics · Physics 2019-12-03 Rouhollh Haji Abdolvahab

We study the noise induced transport of an overdamped Brownian particle in frictional ratchet systems in the presence of external Gaussian white noise fluctuations. The analytical expressions for current and diffusion coefficient are…

Statistical Mechanics · Physics 2007-05-23 Raishma Krishnan , Debasis Dan , A. M. Jayannavar

Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

The migration of a Brownian fluid droplet in a parallel-plate microchannel was investigated using dissipative particle dynamics computer simulations. In a Newtonian solvent, the droplet migrated toward the channel walls due to inertial…

Soft Condensed Matter · Physics 2019-04-16 Michael P. Howard , Thomas M. Truskett , Arash Nikoubashman

In this short note, a correction is made to the recently proposed solution [1] to a 1D biased diffusion model for linear DNA translocation and a new analysis will be given to the data in [1]. It was pointed out [2] by us recently that this…

Soft Condensed Matter · Physics 2013-08-23 Daniel Y. Ling , X. S. Ling

We investigate an intermittent stochastic process, in which the diffusive motion with time-dependent diffusion coefficient $D(t)\sim t^{\alpha-1}$, $\alpha>0$ (scaled Brownian motion), is stochastically reset to its initial position and…

Statistical Mechanics · Physics 2019-07-24 Anna S. Bodrova , Aleksei V. Chechkin , Igor M. Sokolov

Sticky Brownian motion is the simplest example of a diffusion process that can spend finite time both in the interior of a domain and on its boundary. It arises in various applications such as in biology, materials science, and finance.…

Numerical Analysis · Mathematics 2020-07-21 Nawaf Bou-Rabee , Miranda Holmes-Cerfon

We study the phenomena of noise induced transport in frictional ratchet systems. For this we consider a Brownian particle moving in a space dependent frictional medium in the presence of external white noise fluctuations. To get the…

Statistical Mechanics · Physics 2009-07-13 Raishma Krishnan , Debasis Dan , A. M. Jayannavar

Brownian motion provides access to hydrodynamic properties of nanoscale objects independent of their optical resolvability. Here, we present a diffusion-based approach to infer effective particle size distributions of DNA-functionalized…

We investigate diffusion-limited reactions between a diffusing particle and a target site on a semiflexible polymer, a key factor determining the kinetics of DNA-protein binding and polymerization of cytoskeletal filaments. Our theory…

Soft Condensed Matter · Physics 2010-12-08 Yann von Hansen , Roland R. Netz , Michael Hinczewski

Chaperones are binding proteins which work as a driving force to bias the biopolymer translocation by binding to it near the pore and preventing its backsliding. Chaperones may have different spatial distribution. Recently we show the…

Biological Physics · Physics 2019-12-03 Rouhollah Haji Abdolvahab

We study the conformation and dynamics of a single polymer chain that is pulled by a constant force applied at its one end with the other end free. Such a situation is relevant to the growing technology of manipulating individual…

Soft Condensed Matter · Physics 2015-06-04 Takahiro Sakaue , Takuya Saito , Hirofumi Wada

A Brownian ratchet is a one-dimensional diffusion process that drifts toward a minimum of a periodic asymmetric sawtooth potential. A flashing Brownian ratchet is a process that alternates between two regimes, a one-dimensional Brownian…

Probability · Mathematics 2018-02-01 S. N. Ethier , Jiyeon Lee

Brownian dynamics of Dirac fermions in twisted bilayer graphene is investigated within the framework of semiclassical relativistic Langevin equations. We find that under the influence of orthogonal, commensurate ac drives in the periodic…

Mesoscale and Nanoscale Physics · Physics 2023-08-31 Abdullah Yar

Density-dependent diffusion is a widespread phenomenon in nature. We have examined the density-dependent diffusion behavior of some biological processes such as tumor growth and invasion [23]. Here, we extend our previous work by developing…

Statistical Mechanics · Physics 2022-02-14 Ahmed M. Fouad , Marwa M. Fouad

We study subdiffusive overdamped Brownian ratchets periodically rocked by an external zero-mean force in viscoelastic media within the framework of non-Markovian Generalized Langevin equation (GLE) approach and associated multi-dimensional…

Statistical Mechanics · Physics 2013-09-27 Vasyl O. Kharchenko , I. Goychuk

Many forms of cell motility rely on Brownian ratchet mechanisms that involve multiple stochastic processes. We present a computational and theoretical study of the nonequilibrium statistical dynamics of such a many-body ratchet, in the…

Statistical Mechanics · Physics 2014-11-06 Evan Hohlfeld , Phillip L. Geissler

We study the coherence of transport of an overdamped Brownian particle in frictional ratchet system in the presence of external Gaussian white noise fluctuations. The analytical expressions for the particle velocity and diffusion…

Statistical Mechanics · Physics 2009-11-11 Raishma Krishnan , Debasis Dan , A. M. Jayannavar

We have micromachined a silicon-chip device that transports DNA with a Brownian ratchet that rectifies the Brownian motion of microscopic particles. Transport properties for a DNA 50mer agree with theoretical predictions, and the DNA…