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In this work, we developed new mathematical methods for analyzing network topology and applied these methods to the analysis of brain networks. More specifically, we rigorously developed quantitative methods based on complexes constructed…

Neurons and Cognition · Quantitative Biology 2026-04-28 Heitor Baldo

Large spatial datasets often represent a number of spatial point processes generated by distinct entities or classes of events. When crossed with covariates, such as discrete time buckets, this can quickly result in a data set with millions…

Computation · Statistics 2015-10-06 Taylor Arnold

We introduce a method for training neural networks to perform image or volume segmentation in which prior knowledge about the topology of the segmented object can be explicitly provided and then incorporated into the training process. By…

Computer Vision and Pattern Recognition · Computer Science 2020-09-21 James R. Clough , Nicholas Byrne , Ilkay Oksuz , Veronika A. Zimmer , Julia A. Schnabel , Andrew P. King

Graph encoders in AMR-to-text generation models often rely on neighborhood convolutions or global vertex attention. While these approaches apply to general graphs, AMRs may be amenable to encoders that target their tree-like structure. By…

Computation and Language · Computer Science 2021-09-03 Lisa Jin , Daniel Gildea

In the wake of recent advances in experimental methods in neuroscience, the ability to record in-vivo neuronal activity from awake animals has become feasible. The availability of such rich and detailed physiological measurements calls for…

Quantitative Methods · Quantitative Biology 2016-11-03 Gal Mishne , Ronen Talmon , Ron Meir , Jackie Schiller , Uri Dubin , Ronald R. Coifman

We propose a flexible and multi-scale method for organizing, visualizing, and understanding datasets sampled from or near stratified spaces. The first part of the algorithm produces a cover tree using adaptive thresholds based on a…

Computational Geometry · Computer Science 2016-03-01 Paul Bendich , Ellen Gasparovic , Christopher J. Tralie , John Harer

Neural networks and tree ensembles are state-of-the-art learners, each with its unique statistical and computational advantages. We aim to combine these advantages by introducing a new layer for neural networks, composed of an ensemble of…

Machine Learning · Computer Science 2020-07-14 Hussein Hazimeh , Natalia Ponomareva , Petros Mol , Zhenyu Tan , Rahul Mazumder

Neuromorphic engineering aims to advance computing by mimicking the brain's efficient processing, where data is encoded as asynchronous temporal events. This eliminates the need for a synchronisation clock and minimises power consumption…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Ben Walters , Yeshwanth Bethi , Taylor Kergan , Binh Nguyen , Amirali Amirsoleimani , Jason K. Eshraghian , Saeed Afshar , Mostafa Rahimi Azghadi

Neural manifolds summarize the intrinsic structure of the information encoded by a population of neurons. Advances in experimental techniques have made simultaneous recordings from multiple brain regions increasingly commonplace, raising…

Neurons and Cognition · Quantitative Biology 2025-03-27 Iris H. R. Yoon , Gregory Henselman-Petrusek , Yiyi Yu , Robert Ghrist , Spencer LaVere Smith , Chad Giusti

Sparse neural networks attract increasing interest as they exhibit comparable performance to their dense counterparts while being computationally efficient. Pruning the dense neural networks is among the most widely used methods to obtain a…

Neural and Evolutionary Computing · Computer Science 2022-11-11 Zahra Atashgahi , Joost Pieterse , Shiwei Liu , Decebal Constantin Mocanu , Raymond Veldhuis , Mykola Pechenizkiy

Geometric graphs form an important family of hidden structures behind data. In this paper, we develop an efficient and robust algorithm to infer a graph skeleton of a high-dimensional point cloud dataset (PCD). Previously, there has been…

Computational Geometry · Computer Science 2022-10-17 Lucas Magee , Yusu Wang

Neural networks continue to struggle with compositional generalization, and this issue is exacerbated by a lack of massive pre-training. One successful approach for developing neural systems which exhibit human-like compositional…

Artificial Intelligence · Computer Science 2024-12-19 Paul Soulos , Henry Conklin , Mattia Opper , Paul Smolensky , Jianfeng Gao , Roland Fernandez

One of the central challenges facing modern neuroscience is to explain the ability of the nervous system to coherently integrate information across distinct functional modules in the absence of a central executive. To this end Tononi et al.…

Neurons and Cognition · Quantitative Biology 2010-11-30 L. Barnett , C. L. Buckley , S. Bullock

Brain nuclei are clusters of anatomically distinct neurons that serve as important hubs for processing and relaying information in various neural circuits. Fine-scale parcellation of the brain nuclei is vital for a comprehensive…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Haolin He , Ce Zhu , Le Zhang , Yipeng Liu , Xiao Xu , Yuqian Chen , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Lauren J. O'Donnell , Fan Zhang

Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Sunho Kim , Byungjai Kim , HyunWook Park

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

The goal of this thesis is to improve our understanding of the internal mechanisms by which deep artificial neural networks create meaningful representations and are able to generalize. We focus on the challenge of characterizing the…

Machine Learning · Computer Science 2025-10-29 Diego Doimo

We introduce a framework for constructing fractal trees via analytic generator fields, replacing discrete affine transformations and symbolic rewriting rules by the integration of smooth vector fields in an internal state space. In this…

Dynamical Systems · Mathematics 2026-02-04 Henk Mulder

We propose a novel probabilistic dimensionality reduction framework that can naturally integrate the generative model and the locality information of data. Based on this framework, we present a new model, which is able to learn a smooth…

Machine Learning · Statistics 2016-10-18 Li Wang

The segmentation of cranial nerves (CNs) tract provides a valuable quantitative tool for the analysis of the morphology and trajectory of individual CNs. Multimodal CNs tract segmentation networks, e.g., CNTSeg, which combine structural…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Lei Xie , Huajun Zhou , Junxiong Huang , Jiahao Huang , Qingrun Zeng , Jianzhong He , Jiawei Zhang , Baohua Fan , Mingchu Li , Guoqiang Xie , Hao Chen , Yuanjing Feng