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In order to extend the results obtained with minimal lattice models to more realistic systems, we study a model where proteins are described as a chain of 20 kinds of structureless amino acids moving in a continuum space and interacting…

Biomolecules · Quantitative Biology 2009-11-11 A. Amatori , G. Tiana , L. Sutto , J. Ferkinghoff-Borg , A. Trovato , R. A. Broglia

Cyclic redundancy check (CRC) codes check if a codeword is correctly received. This paper presents an algorithm to design CRC codes that are optimized for the code-specific error behavior of a specified feedforward convolutional code. The…

Information Theory · Computer Science 2015-06-10 Chung-Yu Lou , Babak Daneshrad , Richard D. Wesel

mRNA technology has revolutionized vaccine development, protein replacement therapies, and cancer immunotherapies, offering rapid production and precise control over sequence and efficacy. However, the inherent instability of mRNA poses…

Biomolecules · Quantitative Biology 2025-03-26 Max Ward , Mary Richardson , Mihir Metkar

The cyclic shift graph of a monoid is the graph whose vertices are elements of the monoid and whose edges link elements that differ by a cyclic shift. For certain monoids connected with combinatorics, such as the plactic monoid (the monoid…

Combinatorics · Mathematics 2017-07-07 Alan J. Cain , António Malheiro

We investigate the problem of encoding data into an $(n, t)$-break-resilient code ($(n, t)$-BRC), i.e., a collections of sequences of length~$n$ from which the original data can be reconstructed even if they are adversarially broken at up…

Information Theory · Computer Science 2025-09-23 Canran Wang , Jin Sima , Netanel Raviv

An ensemble of directed macromolecules on a lattice is considered, where the constituting molecules are chosen as a random sequence of N different types. The same type of molecules experiences a hard-core (exclusion) interaction. We study…

Biomolecules · Quantitative Biology 2009-11-10 Christopher Moseley , Klaus Ziegler

In network coding, a flag code is a collection of flags, that is, sequences of nested subspaces of a vector space over a finite field. Due to its definition as the sum of the corresponding subspace distances, the flag distance parameter…

Information Theory · Computer Science 2021-12-01 Clementa Alonso-González , Miguel Ángel Navarro-Pérez

Complete complementary codes (CCCs) are highly valuable in the fields of information security, radar and communication. The spectrally null constrained (SNC) problem arises in radar and modern communication systems due to the reservation or…

Information Theory · Computer Science 2025-08-27 Rajen Kumar , Palash Sarkar , Prashant Kumar Srivastava , Sudhan Majhi

One hallmark of human language is its combinatoriality -- reusing a relatively small inventory of building blocks to create a far larger inventory of increasingly complex structures. In this paper, we explore the idea that combinatoriality…

Computation and Language · Computer Science 2024-05-14 Guangyuan Jiang , Matthias Hofer , Jiayuan Mao , Lionel Wong , Joshua B. Tenenbaum , Roger P. Levy

The coding space of protein sequences is shaped by evolutionary constraints set by requirements of function and stability. We show that the coding space of a given protein family--the total number of sequences in that family--can be…

Biomolecules · Quantitative Biology 2020-11-20 Jacopo Marchi , Ezequiel A. Galpern , Rocio Espada , Diego U. Ferreiro , Aleksandra M. Walczak , Thierry Mora

In this paper, we present a novel design strategy of DNA codes with length $3n$ over the non-chain ring $R=\mathbb{Z}_4+u\mathbb{Z}_4+u^2\mathbb{Z}_4$ with $64$ elements and $u^3=1$, where $n$ denotes the length of a code over $R$. We first…

Information Theory · Computer Science 2022-11-28 Shibsankar Das , Krishna Gopal Benerjee , Adrish Banerjee

The purpose of this paper is to present the structure of the linear codes over a finite field with q elements that have a permutation automorphism of order m. These codes can be considered as generalized quasi-cyclic codes. Quasi-cyclic…

Information Theory · Computer Science 2024-02-05 Stefka Bouyuklieva

In this work, we propose a modified four circulant construction for self-dual codes and a bordered version of the construction using the properties of \lambda-circulant and \lambda-reverse circulant matrices. By using the constructions on…

Information Theory · Computer Science 2016-02-24 Abidin Kaya , Bahattin Yildiz , Abdullah Paşa

Effective and reliable data retrieval is critical for the feasibility of DNA storage, and the development of random access efficiency plays a key role in its practicality and reliability. In this paper, we study the Random Access Problem,…

Information Theory · Computer Science 2025-10-10 Anina Gruica , Maria Montanucci , Ferdinando Zullo

In this paper we construct families of bit sequences using combinatorial methods. Each sequence is derived by con- verting a collection of numbers encoding certain combinatorial nu- merics from objects exhibiting symmetry in various…

Combinatorics · Mathematics 2024-05-07 David Allen , Jose J La Luz , Guarionex Salivia , Jonathan Hardwick

Recently, linear codes constructed by defining sets have attracted a lot of study, and many optimal linear codes with a few weights have been produced. The objective of this paper is to present a class of binary linear codes with three…

Information Theory · Computer Science 2016-08-22 Yang Yan , Fei Li , Qiuyan Wang

We study the amount of reliable information that can be stored in a DNA-based storage system with noisy sequencing, where each codeword is composed of short DNA molecules. We analyze a concatenated coding scheme, where the outer code is…

Information Theory · Computer Science 2026-05-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

In this work, we consider the Combinatorial RNA Design problem, a minimal instance of the RNA design problem which aims at finding a sequence that admits a given target as its unique base pair maximizing structure. We provide complete…

Quantitative Methods · Quantitative Biology 2015-06-22 Jozef Haleš , Ján Maňuch , Yann Ponty , Ladislav Stacho

In previous works [physics/0204035, physics/0404052, physics/0509126] a procedure was described for dividing the $3 \times N$-dimensional conformational space of a molecular system into a number of discrete cells, this partition allowed the…

Computational Physics · Physics 2008-12-14 Jacques Gabarro-Arpa

We introduce a novel framework for implementing error-correction in constrained systems. The main idea of our scheme, called Quantized-Constraint Concatenation (QCC), is to employ a process of embedding the codewords of an error-correcting…

Information Theory · Computer Science 2023-02-07 Dor Elimelech , Tom Meyerovitch , Moshe Schwartz