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The knowledge regarding the function of proteins is necessary as it gives a clear picture of biological processes. Nevertheless, there are many protein sequences found and added to the databases but lacks functional annotation. The…

Quantitative Methods · Quantitative Biology 2018-09-13 Anu Vazhayil , Vinayakumar R , Soman KP

We compare a set of convolutional neural network (CNN) architectures for the task of segmenting and detecting human sperm cells in an image taken from a semen sample. In contrast to previous work, samples are not stained or washed to allow…

Computer Vision and Pattern Recognition · Computer Science 2017-04-04 Malte Stær Nissen , Oswin Krause , Kristian Almstrup , Søren Kjærulff , Torben Trindkær Nielsen , Mads Nielsen

Revealing the structure of complex biological macromolecules, such as proteins, is an essential step for understanding the chemical mechanisms that determine the diversity of their functions. Synchrotron based x-ray crystallography and…

Computational approaches to drug discovery can reduce the time and cost associated with experimental assays and enable the screening of novel chemotypes. Structure-based drug design methods rely on scoring functions to rank and predict…

Machine Learning · Statistics 2020-10-19 Matthew Ragoza , Joshua Hochuli , Elisa Idrobo , Jocelyn Sunseri , David Ryan Koes

During the past decade, with the significant progress of computational power as well as ever-rising data availability, deep learning techniques became increasingly popular due to their excellent performance on computer vision problems. The…

Quantitative Methods · Quantitative Biology 2017-07-20 Afshine Amidi , Shervine Amidi , Dimitrios Vlachakis , Vasileios Megalooikonomou , Nikos Paragios , Evangelia I. Zacharaki

Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 Sruthi Krishna , Suganthi S. S , Shivsubramani Krishnamoorthy , Arnav Bhavsar

An important goal in visual recognition is to devise image representations that are invariant to particular transformations. In this paper, we address this goal with a new type of convolutional neural network (CNN) whose invariance is…

Computer Vision and Pattern Recognition · Computer Science 2015-01-08 Julien Mairal , Piotr Koniusz , Zaid Harchaoui , Cordelia Schmid

Convolutional Neural Networks demonstrate high performance on ImageNet Large-Scale Visual Recognition Challenges contest. Nevertheless, the published results only show the overall performance for all image classes. There is no further…

Computer Vision and Pattern Recognition · Computer Science 2015-06-23 Mingming Wang

The COVID19 pandemic has had a detrimental impact on the health and welfare of the worlds population. An important strategy in the fight against COVID19 is the effective screening of infected patients, with one of the primary screening…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Nafiz Fahad , Fariha Jahan , Md Kishor Morol , Rasel Ahmed , Md. Abdullah-Al-Jubair

Deep learning, especially convolutional neural networks, has triggered accelerated advancements in computer vision, bringing changes into our daily practice. Furthermore, the standardized deep learning modules (also known as backbone…

Computer Vision and Pattern Recognition · Computer Science 2022-12-02 Hongzhi Zhu , Robert Rohling , Septimiu Salcudean

Determining the material category of a surface from an image is a demanding task in perception that is drawing increasing attention. Following the recent remarkable results achieved for image classification and object detection utilising…

Computer Vision and Pattern Recognition · Computer Science 2017-03-17 Grigorios Kalliatakis , Georgios Stamatiadis , Shoaib Ehsan , Ales Leonardis , Juergen Gall , Anca Sticlaru , Klaus D. McDonald-Maier

Serial crystallography is the field of science that studies the structure and properties of crystals via diffraction patterns. In this paper, we introduce a new serial crystallography dataset comprised of real and synthetic images; the…

Generative models trained on public databases of protein structures, most of which have been determined by X-ray crystallography, now provide powerful priors for structure prediction. However, they are not readily conditioned on the…

Machine Learning · Computer Science 2026-05-18 Minseo Kim , Huanghao Mai , Jay Shenoy , Alec Follmer , Gordon Wetzstein , Frederic Poitevin

Machine learning and artificial intelligence are fast-growing fields of research in which data is used to train algorithms, learn patterns, and make predictions. This approach helps to solve seemingly intricate problems with significant…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Shereiff Garrett , Abhinav Adhikari , Sarina Gautam , DaShawn Marquis Morris , Chandra Mani Adhikari

Understanding complex biological macromolecules, especially proteins, is vital for grasping their diverse chemical functions with direct impact in biology and pharmacology. While techniques like X-ray crystallography and cryo-electron…

Biomolecules · Quantitative Biology 2024-04-12 S. H. Mejias , A. L. Cortajarena , R. Mincigrucci , C. Svetina , C. Masciovecchio

Humans are able to categorize images very efficiently, in particular to detect the presence of an animal very quickly. Recently, deep learning algorithms based on convolutional neural networks (CNNs) have achieved higher than human accuracy…

Neurons and Cognition · Quantitative Biology 2023-06-01 Jean-Nicolas Jérémie , Laurent U Perrinet

Proteins play a central role in biology from immune recognition to brain activity. While major advances in machine learning have improved our ability to predict protein structure from sequence, determining protein function from structure…

Fruit recognition using Deep Convolutional Neural Network (CNN) is one of the most promising applications in computer vision. In recent times, deep learning based classifications are making it possible to recognize fruits from images.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-28 Shadman Sakib , Zahidun Ashrafi , Md. Abu Bakr Siddique

In recent years, machine learning has been proposed as a promising strategy to build accurate scoring functions for computational docking finalized to numerically empowered drug discovery. However, the latest studies have suggested that…

Quantitative Methods · Quantitative Biology 2023-02-17 F. Pellicani , D. Dal Ben , A. Perali , S. Pilati

Convolutional Neural Networks are a well-known staple of modern image classification. However, it can be difficult to assess the quality and robustness of such models. Deep models are known to perform well on a given training and estimation…

Machine Learning · Statistics 2018-02-06 Alexey Chaplygin , Joshua Chacksfield