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Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit. Relying on either four primitive bases or independently…

Genomics · Quantitative Biology 2025-11-20 Siyuan Li , Kai Yu , Anna Wang , Zicheng Liu , Chang Yu , Jingbo Zhou , Qirong Yang , Yucheng Guo , Xiaoming Zhang , Stan Z. Li

We investigate star-galaxy classification for astronomical surveys in the context of four methods enabling the interpretation of black-box machine learning systems. The first is outputting and exploring the decision boundaries as given by…

Instrumentation and Methods for Astrophysics · Physics 2018-09-26 Xan Morice-Atkinson , Ben Hoyle , David Bacon

As in many other scientific domains, we face a fundamental problem when using machine learning to identify proteins from mass spectrometry data: large ground truth datasets mapping inputs to correct outputs are extremely difficult to…

With the advent of quantum and quantum-inspired machine learning, adapting the structure of learning models to match the structure of target datasets has been shown to be crucial for obtaining high performance. Probabilistic models based on…

Quantum Physics · Physics 2022-11-30 Atithi Acharya , Manuel Rudolph , Jing Chen , Jacob Miller , Alejandro Perdomo-Ortiz

Learning embedding functions, which map semantically related inputs to nearby locations in a feature space supports a variety of classification and information retrieval tasks. In this work, we propose a novel, generalizable and fast method…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Hong Xuan , Richard Souvenir , Robert Pless

We present three related ways of using Transfer Learning to improve feature selection. The three methods address different problems, and hence share different kinds of information between tasks or feature classes, but all three are based on…

Machine Learning · Computer Science 2009-05-26 Paramveer S. Dhillon , Dean Foster , Lyle Ungar

We present a three-pronged approach to improving Statistical Machine Translation (SMT), building on recent success in the application of neural networks to SMT. First, we propose new features based on neural networks to model various…

Computation and Language · Computer Science 2015-06-03 Hendra Setiawan , Zhongqiang Huang , Jacob Devlin , Thomas Lamar , Rabih Zbib , Richard Schwartz , John Makhoul

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types.…

Artificial Intelligence · Computer Science 2024-12-06 Yoav Kan-Tor , Michael Morris Danziger , Eden Zohar , Matan Ninio , Yishai Shimoni

Deep Learning is considered to be a quite young in the area of machine learning research, found its effectiveness in dealing complex yet high dimensional dataset that includes but limited to images, text and speech etc. with multiple levels…

Computer Vision and Pattern Recognition · Computer Science 2016-10-19 Mrutyunjaya Panda

We present an automated approach for identifying and annotating motifs and domains in protein sequences, using pretrained Protein Language Models (PLMs) and Concept Activation Vectors (CAVs), adapted from interpretability research in…

Quantitative Methods · Quantitative Biology 2025-11-27 Ahmad Shamail , Claire D. McWhite

Matched filters are widely used to localise signal patterns due to their high efficiency and interpretability. However, their effectiveness deteriorates for low signal-to-noise ratio (SNR) signals, such as those recorded on edge devices,…

Signal Processing · Electrical Eng. & Systems 2025-09-01 Haozhe Tian , Qiyu Rao , Nina Moutonnet , Pietro Ferraro , Danilo Mandic

Machine Learning methods have of late made significant efforts to solving multidisciplinary problems in the field of cancer classification using microarray gene expression data. Feature subset selection methods can play an important role in…

Computational Engineering, Finance, and Science · Computer Science 2013-03-04 G. Prat , Ll. Belanche

Deep learning-based fault diagnosis (FD) approaches require a large amount of training data, which are difficult to obtain since they are located across different entities. Federated learning (FL) enables multiple clients to collaboratively…

Machine Learning · Computer Science 2023-10-16 Jixuan Cui , Jun Li , Zhen Mei , Kang Wei , Sha Wei , Ming Ding , Wen Chen , Song Guo

This study assesses the efficiency of several popular machine learning approaches in the prediction of molecular binding affinity: CatBoost, Graph Attention Neural Network, and Bidirectional Encoder Representations from Transformers. The…

Machine Learning · Computer Science 2020-12-16 Oleksandr Gurbych , Maksym Druchok , Dzvenymyra Yarish , Sofiya Garkot

Automated Machine Learning with ensembling (or AutoML with ensembling) seeks to automatically build ensembles of Deep Neural Networks (DNNs) to achieve qualitative predictions. Ensemble of DNNs are well known to avoid over-fitting but they…

Machine Learning · Computer Science 2022-08-31 Pierrick Pochelu , Serge G. Petiton , Bruno Conche

Machine learning force fields (MLFFs) are gradually evolving towards enabling molecular dynamics simulations of molecules and materials with ab initio accuracy but at a small fraction of the computational cost. However, several challenges…

Ensuring software quality remains a critical challenge in complex and dynamic development environments, where software defects can result in significant operational and financial risks. This paper proposes an innovative framework for…

Software Engineering · Computer Science 2024-12-17 Mohsen Hesamolhokama , Amirahmad Shafiee , Mohammadreza Ahmaditeshnizi , Mohammadamin Fazli , Jafar Habibi

Transposable Elements (TEs) or jumping genes are the DNA sequences that have an intrinsic capability to move within a host genome from one genomic location to another. Studies show that the presence of a TE within or adjacent to a…

Machine Learning · Computer Science 2019-08-27 Manisha Panta , Avdesh Mishra , Md Tamjidul Hoque , Joel Atallah

Recommendation systems and computing advertisements have gradually entered the field of academic research from the field of commercial applications. Click-through rate prediction is one of the core research issues because the prediction…

Machine Learning · Computer Science 2019-02-26 Li Zhang , Weichen Shen , Shijian Li , Gang Pan

Decision trees and random forest remain highly competitive for classification on medium-sized, standard datasets due to their robustness, minimal preprocessing requirements, and interpretability. However, a single tree suffers from high…

Machine Learning · Statistics 2025-12-02 Cencheng Shen , Yuexiao Dong , Carey E. Priebe