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Background: Elucidating gene regulatory networks is crucial for understanding normal cell physiology and complex pathologic phenotypes. Existing computational methods for the genome-wide ``reverse engineering'' of such networks have been…

Understanding relationship between noisy dynamics and biological network architecture is a fundamentally important question, particularly in order to elucidate how cells encode and process information. We analytically and numerically…

Molecular Networks · Quantitative Biology 2011-10-12 Jaewook Joo , Jinmyung Choi

Adding noises to artificial neural network(ANN) has been shown to be able to improve robustness in previous work. In this work, we propose a new technique to compute the pathwise stochastic gradient estimate with respect to the standard…

Machine Learning · Computer Science 2021-02-10 Li Xiao , Zeliang Zhang , Yijie Peng

Speech emotion recognition (SER) often experiences reduced performance due to background noise. In addition, making a prediction on signals with only background noise could undermine user trust in the system. In this study, we propose a…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-06 Yu-Wen Chen , Julia Hirschberg , Yu Tsao

Owing to flexible architectures of deep convolutional neural networks (CNNs), CNNs are successfully used for image denoising. However, they suffer from the following drawbacks: (i) deep network architecture is very difficult to train. (ii)…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Chunwei Tian , Yong Xu , Lunke Fei , Junqian Wang , Jie Wen , Nan Luo

Biological networks often encapsulate promotion/inhibition as signed edge-weights of a graph. Nodes may correspond to genes assigned expression levels (mass) of respective proteins. The promotion/inhibition nature of co-expression between…

Molecular Networks · Quantitative Biology 2023-08-21 Anqi Dong , Tryphon T. Georgiou , Allen Tannenbaum

Clustering is a fundamental task in network analysis, essential for uncovering hidden structures within complex systems. Edge clustering, which focuses on relationships between nodes rather than the nodes themselves, has gained increased…

Computation · Statistics 2025-07-14 Haomin Li , Daniel K. Sewell

High-throughput data analyses are becoming common in biology, communications, economics and sociology. The vast amounts of data are usually represented in the form of matrices and can be considered as knowledge networks. Spectra-based…

Quantitative Methods · Quantitative Biology 2010-01-06 Viet-Anh Nguyen , Zdena Koukolikova-Nicola , Franco Bagnoli , Pietro Lio

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. However, low-count PET scans often suffer from high image noise, which can negatively impact image…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Huidong Xie , Qiong Liu , Bo Zhou , Xiongchao Chen , Xueqi Guo , Chi Liu

The proliferation of Artificial Neural Networks (ANNs) has led to increased energy consumption, raising concerns about their sustainability. Spiking Neural Networks (SNNs), which are inspired by biological neural systems and operate using…

Neural and Evolutionary Computing · Computer Science 2024-09-25 Lucas Deckers , Benjamin Vandersmissen , Ing Jyh Tsang , Werner Van Leekwijck , Steven Latré

Image classification has been a popular task due to its feasibility in real-world applications. Training neural networks by feeding them RGB images has demonstrated success over it. Nevertheless, improving the classification accuracy and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Tianhao Bu , Michalis Lazarou , Tania Stathaki

In wireless networks characterized by dense connectivity, the significant signaling overhead generated by distributed link scheduling algorithms can exacerbate issues like congestion, energy consumption, and radio footprint expansion. To…

Networking and Internet Architecture · Computer Science 2025-09-09 Zhongyuan Zhao , Gunjan Verma , Ananthram Swami , Santiago Segarra

We propose an interpretable graph neural network framework to denoise single or multiple noisy graph signals. The proposed graph unrolling networks expand algorithm unrolling to the graph domain and provide an interpretation of the…

Signal Processing · Electrical Eng. & Systems 2021-09-08 Siheng Chen , Yonina C. Eldar , Lingxiao Zhao

Peer effect estimation requires precise network measurement, yet most empirical networks are noisy, rendering standard estimators inconsistent. To address measurement error in networks, we propose a method to estimate peer effects in…

Methodology · Statistics 2026-05-06 Alex Hayes , Keith Levin

Bayesian neural networks (BNNs) augment deep networks with uncertainty quantification by Bayesian treatment of the network weights. However, such models face the challenge of Bayesian inference in a high-dimensional and usually…

Machine Learning · Computer Science 2021-03-30 Zhijie Deng , Yucen Luo , Jun Zhu , Bo Zhang

One of the primary goals of systems neuroscience is to relate the structure of neural circuits to their function, yet patterns of connectivity are difficult to establish when recording from large populations in behaving organisms. Many…

Machine Learning · Computer Science 2020-12-08 Anne Draelos , Eva A. Naumann , John M. Pearson

The problem of reconstructing and identifying intracellular protein signaling and biochemical networks is of critical importance in biology today. We sought to develop a mathematical approach to this problem using, as a test case, one of…

Data Analysis, Statistics and Probability · Physics 2012-06-15 D. Napoletani , T. Sauer , D. C. Struppa , E. Petricoin , L. Liotta

Sparse neural networks are important for achieving better generalization and enhancing computation efficiency. This paper proposes a novel learning approach to obtain sparse fully connected layers in neural networks (NNs) automatically. We…

Machine Learning · Computer Science 2021-04-28 Mengqiao Han , Xiabi Liu , Zhaoyang Hai , Zhengwen Li

We analyze the landscape and training dynamics of diagonal linear networks in a linear regression task, with the network parameters being perturbed by small isotropic normal noise. The addition of such noise may be interpreted as a…

Machine Learning · Computer Science 2025-03-18 Gabriel Clara , Sophie Langer , Johannes Schmidt-Hieber

Node classification in graphs aims to predict the categories of unlabeled nodes by utilizing a small set of labeled nodes. However, weighted graphs often contain noisy edges and anomalous edge weights, which can distort fine-grained…

Machine Learning · Computer Science 2025-04-01 Tingting Wang , Jiaxin Su , Haobing Liu , Ruobing Jiang
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