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In this paper, we study an optimal control problem for a two-dimensional Cahn-Hilliard-Darcy system with mass sources that arises in the modeling of tumor growth. The aim is to monitor the tumor fraction in a finite time interval in such a…

Analysis of PDEs · Mathematics 2023-07-28 Juergen Sprekels , Hao Wu

A quality-Bayesian approach, combining the direct sampling method and the Bayesian inversion, is proposed to reconstruct the locations and intensities of the unknown acoustic sources using partial data. First, we extend the direct sampling…

Numerical Analysis · Mathematics 2020-04-10 Zhaoxing Li , Yanfang Liu , Jiguang Sun , Liwei Xu

The Bayesian methods for linear inverse problems is studied using hierarchical Gaussian models. The problems are considered with different discretizations, and we analyze the phenomena which appear when the discretization becomes finer. A…

Statistics Theory · Mathematics 2009-09-14 Tapio Helin , Matti Lassas

Data collected by the Interstellar Boundary Explorer (IBEX) satellite, recording heliospheric energetic neutral atoms (ENAs), exhibit a phenomenon that has caused space scientists to revise hypotheses about the physical processes, and…

This paper addresses the issue of inversion in cases where (1) the observation system is modeled by a linear transformation and additive noise, (2) the problem is ill-posed and regularization is introduced in a Bayesian framework by an a…

Machine Learning · Statistics 2026-02-12 Jean-François Giovannelli

During the last decades, medical observations and multiscale data concerning tumor growth are mounting. At the same time, contemporary imaging techniques well established in clinical practice, provide a variety of information on real-time,…

Tissues and Organs · Quantitative Biology 2017-12-11 Markos Antonopoulos , Georgios Stamatakos

In indirect measurements, the measurand is determined by solving an inverse problem which requires a model of the measurement process. Such models are often approximations and introduce systematic errors leading to a bias of the posterior…

Methodology · Statistics 2025-09-22 Maren Casfor , Philipp Trunschke , Sebastian Heidenreich , Nando Hegemann

In this paper, we study a system of three evolutionary operator equations involving fractional powers of selfadjoint, monotone, unbounded, linear operators having compact resolvents. This system constitutes a generalization of a phase field…

Analysis of PDEs · Mathematics 2019-06-27 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

Tracer-kinetic analysis of dynamic contrast-enhanced magnetic resonance imaging data is commonly performed with the well-known Tofts model and nonlinear least squares (NLLS) regression. This approach yields point estimates of model…

Medical Physics · Physics 2020-01-08 Andreas Mittermeier , Birgit Ertl-Wagner , Jens Ricke , Olaf Dietrich , Michael Ingrisch

We consider a fully practical finite element approximation of a diffuse interface model for tumour growth that takes the form of a degenerate parabolic system. In addition to showing stability bounds for the approximation, we prove…

Numerical Analysis · Mathematics 2022-02-07 Joe Eyles , Robert Nürnberg , Vanessa Styles

Motivation: A branching processes model yields an unevenly stochastically distributed dataset that consists of sparse and dense regions. This work addresses the problem of precisely evaluating parameters for such a model. Applying a…

Machine Learning · Statistics 2023-05-09 Iurii S. Nagornov

Inverse problems are ubiquitous in the sciences and engineering. Two categories of inverse problems concerning a physical system are (1) estimate parameters in a model of the system from observed input-output pairs and (2) given a model of…

Methodology · Statistics 2023-12-05 Faaiq G. Waqar , Swati Patel , Cory M. Simon

High-dimensional Bayesian procedures often exhibit behavior that is effectively low dimensional, even when the ambient parameter space is large or infinite-dimensional. This phenomenon underlies the success of shrinkage priors,…

Statistics Theory · Mathematics 2025-12-30 Sayantan Banerjee

We study an inverse random obstacle scattering problems in $\mathbb{R}^2$ where the scatterer is formulated by a Gaussian process defined on the angular parameter domain. Equipped with a modified covariance function which is mathematically…

Numerical Analysis · Mathematics 2026-02-02 Zhiqi Sun , Xiang Xu , Yiwen Lin

In statistical applications, it is common to encounter parameters supported on a varying or unknown dimensional space. Examples include the fused lasso regression, the matrix recovery under an unknown low rank, etc. Despite the ease of…

Methodology · Statistics 2022-10-04 Maoran Xu , Hua Zhou , Yujie Hu , Leo L. Duan

The three and five-dimensional convex sets of two-level complex and quaternionic quantum systems are studied in the Bayesian thermostatistical framework introduced by Lavenda. Associated with a given parameterization of each such set is a…

Quantum Physics · Physics 2007-05-23 Paul B. Slater

In the present work, we develop a comprehensive and rigorous analytical framework for a non-local phase-field model that describes tumour growth dynamics. The model is derived by coupling a non-local Cahn-Hilliard equation with a parabolic…

Analysis of PDEs · Mathematics 2025-03-14 Maurizio Grasselli , Luca Melzi , Andrea Signori

Tensor-valued data are being encountered increasingly more commonly, in the biological, natural as well as the social sciences. The learning of the unknown model parameter vector given such data, involves covariance modelling of such data,…

Applications · Statistics 2015-06-19 Kangrui Wang , Dalia Chakrabarty

In Structural Health Monitoring (SHM), the recovery of distributed mechanical parameters from sparse data is often ill-posed, raising critical questions about identifiability and the reliability of inferred states. While deterministic…

Computational Engineering, Finance, and Science · Computer Science 2025-11-24 Tammam Bakeer , Max Herbers , Steffen Marx

A novel numerical technique has been proposed to solve a two-phase tumour growth model in one spatial dimension without needing to account for the boundary dynamics explicitly. The equivalence to the standard definition of a weak solution…

Numerical Analysis · Mathematics 2019-02-19 Gopikrishnan C. Remesan
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