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Background: Phage therapy shows promise for treating antibiotic-resistant Klebsiella infections. Identifying phage depolymerases that target Klebsiella capsular polysaccharides is crucial, as these capsules contribute to biofilm formation…

Genomics · Quantitative Biology 2025-01-29 George Wright , Slawomir Michniewski , Eleanor Jameson , Fayyaz ul Amir Afsar Minhas

Network representation learning, as an approach to learn low dimensional representations of vertices, has attracted considerable research attention recently. It has been proven extremely useful in many machine learning tasks over large…

Machine Learning · Computer Science 2019-06-11 Hao Peng , Jianxin Li , Hao Yan , Qiran Gong , Senzhang Wang , Lin Liu , Lihong Wang , Xiang Ren

Large language models (LLMs) have demonstrated strong code generation capabilities, yet the runtime performance of generated code is not guaranteed, and there have been few attempts to train LLMs using runtime performance as a reward in the…

Machine Learning · Computer Science 2026-02-13 Ryo Mikasa , Shun-ichiro Hayashi , Daichi Mukunoki , Tetsuya Hoshino , Takahiro Katagiri

Cyber-security garnered significant attention due to the increased dependency of individuals and organizations on the Internet and their concern about the security and privacy of their online activities. Several previous machine learning…

Cryptography and Security · Computer Science 2020-08-11 MohammadNoor Injadat , Abdallah Moubayed , Ali Bou Nassif , Abdallah Shami

Learning a kernel matrix from relative comparison human feedback is an important problem with applications in collaborative filtering, object retrieval, and search. For learning a kernel over a large number of objects, existing methods face…

Machine Learning · Computer Science 2015-01-13 Eric Heim , Matthew Berger , Lee M. Seversky , Milos Hauskrecht

In this work we address the task of observing the performance of a semantic segmentation deep neural network (DNN) during online operation, i.e., during inference, which is of high importance in safety-critical applications such as…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Marvin Klingner , Andreas Bär , Marcel Mross , Tim Fingscheidt

A major challenge in training large-scale machine learning models is configuring the training process to maximize model performance, i.e., finding the best training setup from a vast design space. In this work, we unlock a gradient-based…

Machine Learning · Statistics 2025-03-19 Logan Engstrom , Andrew Ilyas , Benjamin Chen , Axel Feldmann , William Moses , Aleksander Madry

Large language models can predict real-valued quantities from heterogeneous inputs such as text, code, and molecular strings, but most training objectives score each decoded floating-point number independently, improving point estimates…

Machine Learning · Computer Science 2026-05-21 Jungsoo Park , Hyungjoo Chae , Ethan Mendes , Jay DeYoung , Varsha Kishore , Wei Xu , Alan Ritter

The discovery of peptides having high biological activity is very challenging mainly because there is an enormous diversity of compounds and only a minority have the desired properties. To lower cost and reduce the time to obtain promising…

Quantitative Methods · Quantitative Biology 2014-04-11 Sébastien Giguère , François Laviolette , Mario Marchand , Denise Tremblay , Sylvain Moineau , Éric Biron , Jacques Corbeil

In recent years, deep learning based visual tracking methods have obtained great success owing to the powerful feature representation ability of Convolutional Neural Networks (CNNs). Among these methods, classification-based tracking…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yihan Du , Yan Yan , Si Chen , Yang Hua

In the past decade, the cyber-crime related to mobile devices has increased. Mobile devices, especially the ones running on Android operating system are particularly interesting to malware creators, as the users often keep the biggest…

Cryptography and Security · Computer Science 2019-10-24 Nikola Milosevic , Junfan Huang

Online reconstruction is key for monitoring purposes and real time analysis in High Energy and Nuclear Physics experiments. A necessary component of reconstruction algorithms is particle identification that combines information left by a…

Instrumentation and Detectors · Physics 2026-01-13 Richard Tyson , Gagik Gavalian

Point cloud segmentation (PCS) aims to make per-point predictions and enables robots and autonomous driving cars to understand the environment. The range image is a dense representation of a large-scale outdoor point cloud, and segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Bike Chen , Chen Gong , Antti Tikanmäki , Juha Röning

Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…

Medical Physics · Physics 2022-08-09 Alma Eguizabal , Ozan Öktem , Mats U. Persson

The spatiotemporal resolution of Partial Differential Equations (PDEs) plays important roles in the mathematical description of the world's physical phenomena. In general, scientists and engineers solve PDEs numerically by the use of…

Artificial Intelligence · Computer Science 2023-06-29 Lucas Meyer , Marc Schouler , Robert Alexander Caulk , Alejandro Ribés , Bruno Raffin

Mathematical word problem-solving has long been recognized as a complex task for small language models (SLMs). A recent study hypothesized that the smallest model size, needed to achieve over 80% accuracy on the GSM8K benchmark, is 34…

Computation and Language · Computer Science 2024-02-26 Arindam Mitra , Hamed Khanpour , Corby Rosset , Ahmed Awadallah

Modern decision-making systems, from robots to web recommendation engines, are expected to adapt: to user preferences, changing circumstances or even new tasks. Yet, it is still uncommon to deploy a dynamically learning agent (rather than a…

Machine Learning · Computer Science 2022-11-15 Shengpu Tang , Felipe Vieira Frujeri , Dipendra Misra , Alex Lamb , John Langford , Paul Mineiro , Sebastian Kochman

Although deep convolutional neural networks (DCNNs) have achieved significant accuracy in skin lesion classification comparable or even superior to those of dermatologists, practical implementation of these models for skin cancer screening…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Shuwei Shen , Mengjuan Xu , Fan Zhang , Pengfei Shao , Honghong Liu , Liang Xu , Chi Zhang , Peng Liu , Zhihong Zhang , Peng Yao , Ronald X. Xu

Distributed online learning is gaining increased traction due to its unique ability to process large-scale datasets and streaming data. To address the growing public awareness and concern on privacy protection, plenty of algorithms have…

Machine Learning · Computer Science 2024-08-27 Ziqin Chen , Yongqiang Wang

In this paper, we address the challenges of online Continual Learning (CL) by introducing a density distribution-based learning framework. CL, especially the Class Incremental Learning, enables adaptation to new test distributions while…

Machine Learning · Computer Science 2023-11-27 Shilin Zhang , Jiahui Wang
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